Vitamin D3 with Vitamin B12, Vitamin B6, Vitamin B9, and Calcium syrup is an oral nutritional supplement. This combination is used to treat calcium and various vitamins deficiencies. It helps strengthen bones and teeth, supports healthy nerve function, improves calcium absorption, and promotes red blood cell formation. 

Vitamin D3 helps the body absorb calcium efficiently, while calcium is essential for maintaining strong bones and teeth. Vitamin B12 supports healthy nerves and red blood cell production. Vitamin B6 plays an important role in brain function, metabolism, and immunity. Vitamin B9 (folic acid) helps in DNA formation, cell growth, and the production of healthy red blood cells. Together, these nutrients help improve bone health, energy levels, nerve function, and overall well-being. 

Common side effects of Vitamin D3 with Vitamin B12, Vitamin B6, Vitamin B9 and Calcium include mild stomach upset, constipation, nausea, bloating, diarrhea, headache, and a metallic taste in the mouth. These effects are usually mild and temporary. This medicine should be taken only as prescribed by your doctor, especially if you have kidney disease, high calcium levels, or are taking other vitamin or mineral supplements.  

Vitamin D3 with Vitamin B12, Vitamin B6, Vitamin B9 And Calcium are used to treat the following conditions: 

1. Calcium deficiency  
2. Vitamin D deficiency  
3. Vitamin B12 and B6 deficiency  
4. Folic acid deficiency  
5. Weak bones (osteoporosis)  
6. Bone pain  
7. Muscle weakness  
8. Fatigue due to nutritional deficiencies  
9. Poor nerve function  
10. Nutritional deficiencies during growth, pregnancy, or recovery                          

More Common

1. Nausea  
2. Stomach discomfort  
3. Constipation  
4. Loose stools or diarrhea  
5. Vomiting  
6. Headache  
7. Metallic taste in mouth                    

Less Common 

1. Bloating  
2. Loss of appetite  
3. Skin rash  
4. Itching  
5. Dizziness  
6. Allergic reaction              

This syrup works by supplying essential vitamins and minerals required for healthy bones, nerves, muscles, and blood cells. Vitamin D3 improves calcium absorption from the intestine. Calcium helps build and maintain strong bones and teeth. Vitamin B12 supports healthy nerve cells and red blood cell production. Vitamin B6 helps convert food into energy and supports brain and immune function. Vitamin B9 (folic acid) is essential for DNA synthesis, cell growth, and the formation of healthy red blood cells. Together, these nutrients correct deficiencies, improve bone strength, reduce weakness, and support overall health. 

Avoid taking Vitamin D3 with Vitamin B12, Vitamin B6, Vitamin B9 And Calcium with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

There are no major food restrictions. However, take this medicine in the dose recommended by your doctor. Avoid excessive calcium supplements unless advised.

Daily dose

Take Vitamin D3 with Vitamin B12, Vitamin B6, Vitamin B9 And Calcium exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Calcium 

The recommended daily requirement of calcium is about 1000 mg per day for adults. In women above 50 years, it increases to about 1200 mg per day. During pregnancy, the requirement is about 1000 mg per day. In children, it ranges from 700–1300 mg depending on age. 

Vitamin D3 

The recommended daily intake of vitamin D3 for adults is around 600–800 IU. Older adults over 70 years may need 800 IU daily. 

Vitamin B12 

The recommended daily intake of vitamin B12 for adults is 2.4 mcg. During pregnancy, it increases to about 2.6 mcg, and during breastfeeding, it is around 2.8 mcg per day.

Vitamin B6 

The recommended daily intake of vitamin B6 for adults is about 1.3–1.7 mg depending on age and sex. Pregnant women require about 1.9 mg, while breastfeeding women need 2 mg daily.

Vitamin B9 (Folic Acid) 

Adults require 400 mcg DFE (Dietary Folate Equivalents) daily. Pregnant women require 600 mcg DFE, while breastfeeding women need 500 mcg DFE daily.

Calcium 

Calcium is found in milk, curd, cheese, paneer, green leafy vegetables, almonds, sesame seeds, and fortified foods.

Vitamin D3

Vitamin D3 is obtained from sunlight exposure, fatty fish, egg yolk, liver, and fortified dairy products.

Vitamin B12

Vitamin B12 is found in milk, curd, cheese, eggs, fish, chicken, meat, liver, and fortified cereals. Vegetarians may need supplements if intake is low.

Vitamin B6

Bananas, potatoes, chickpeas, poultry, fish, whole grains, nuts, spinach, and fortified cereals.

Vitamin B9 (Folic Acid)

Spinach, fenugreek leaves, broccoli, beans, lentils, peas, oranges, avocados, peanuts, and fortified cereals.

Which foods are rich in Vitamin B6? 

Good sources of vitamin b6 include bananas, potatoes, chickpeas, spinach, whole grains, chicken, fish, eggs, nuts, and fortified breakfast cereals. Vitamin B6 is naturally found in many everyday foods. Eating a balanced diet with these foods usually provides enough vitamin B6 for most people. 

What Is Vitamin B6 Deficiency? 

Vitamin B6 deficiency occurs when the body does not get enough vitamin B6. It can cause tiredness, weakness, skin rashes, cracked lips, numbness or tingling in the hands and feet, mood changes, and anemia. It is more common in people with poor nutrition, kidney disease, or certain long-term illnesses.

Which Foods Are Rich in Folic Acid? 

Folic acid (vitamin B9) is found in spinach, fenugreek leaves, broccoli, cabbage, beans, lentils, peas, oranges, avocados, peanuts, asparagus, and fortified cereals. Including these foods regularly can help maintain healthy folate levels. 

What Are the Side Effects of Folic Acid? 

Folic acid is generally safe when taken in the recommended amount. However, taking high doses may cause nausea, bloating, stomach discomfort, loss of appetite, or trouble sleeping in some people. Long-term use of very high doses should only be done under a doctor’s guidance. 

What Are the Benefits of Folic Acid for Women? 

Folic acid helps women produce healthy red blood cells and supports normal cell growth. It is especially important before and during pregnancy because it helps reduce the risk of birth defects in the baby’s brain and spine. It also supports overall health by helping the body make DNA and maintain healthy tissues. 

Calcium Is Found in Which Foods? 

Calcium is found in milk, curd, cheese, paneer, yogurt, ragi, sesame seeds, almonds, tofu, soy products, green leafy vegetables like spinach, and fortified foods and drinks. These foods help keep bones and teeth strong. 

What Is Vitamin D3 Deficiency? 

Vitamin D3 deficiency happens when the body does not have enough vitamin D. It can lead to weak bones, bone pain, muscle weakness, tiredness, increase risk of fractures, and if the deficiency persists for longer duration, it increases the intensity of infection and cause hair fall. People who get very little sunlight or have poor dietary intake are more likely to develop this deficiency. 

Which Foods Contain Vitamin D3? 

Vitamin D3 is found in fatty fish such as salmon, sardines, and mackerel, egg yolks, liver, fortified milk, fortified dairy products, and fortified cereals. Sunlight is also one of the best natural sources of vitamin D3, as the skin produces it when exposed to sunlight.

1. Vitamin D [Internet]. medlineplus.gov. Available from 
2. National Institutes of Health. Office of Dietary Supplements – Vitamin B12 [Internet]. Nih.gov. National Institutes of Health; 2024. Available from 
3. National Institutes of Health. Calcium [Internet]. National Institutes of Health Office of Dietary Supplements. 2024. Available from 
4. National Institutes of Health. Office of Dietary Supplements – Vitamin B6 [Internet]. Nih.gov. 2023 [cited 2026 July 30]. Available from 
5. National Institutes of Health. Office of Dietary Supplements – Vitamin B6 [Internet]. Nih.gov. 2023 [cited 2026 July 30]. Available from 
6. Harvard T.H. Chan School of Public Health. Vitamin B6 [Internet]. The Nutrition Source. 2019 June [cited 2026 July 30]. Available from 
7. Harvard T.H. Chan. Folate (Folic Acid) – Vitamin B9 [Internet]. The Nutrition Source. 2012 Sept [cited 2026 July 30]. Available from 
8. National Institutes of Health. Office of Dietary Supplements – Folate [Internet]. Nih.gov. National Institutes of Health; 2022 [cited 2026 July 30]. Available from