Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg are combination medicines that lower blood sugar in different ways. Metformin reduces blood glucose sugar made by the liver and improves insulin action, while dapagliflozin and sitagliptin helps to remove excess sugar through urine. Together, they help control diabetes, may aid weight loss, and offer heart and kidney benefits. This medicine can cause stomach upset, especially if it is taken without food. Avoid consuming alcohol with this to prevent lactic acidosis. Taking more than 2500 mg of this combination medicine can cause overdosing effects like low blood sugar, low blood pressure, and unconsciousness.

Dapagliflozin 10 mg + Metformin 1000 mg + sitagliptin 100 mg is an oral combination medicine belonging to the category of antidiabetic drugs. Dapagliflozin 10 mg + Metformin 1000 mg + sitagliptin 100 mg is used for the management of Type 2 Diabetes mellitus

More Common

1. Abdominal or stomach discomfort 
2. Cough or hoarseness 
3. Decreased appetite 
4. Diarrhea 
5. Fast or shallow breathing 
6. Fever or chills 
7. General feeling of discomfort 
8. Lower back or side pain 
9. Muscle pain or cramping 
10. Painful or difficult urination 
11. Sleepiness 
12. Anxiety 
13. Bladder pain 
14. Bloody or cloudy urine 
15. Blurred vision 
16. Chills 
17. Cold sweats 
18. Confusion 
19. Cool, pale skin 
20. Decreased frequency or amount of urine 

Less Common 

1. Anxiety 
2. Blurred vision 
3. Chest discomfort 
4. Cold sweats 
5. Coma 
6. Confusion 
7. Cool, pale skin 
8. Depression 
9. Difficult or labored breathing 
10. Dizziness 
11. Fast, irregular, pounding, or racing heartbeat or pulse 
12. Feeling of warmth 
13. Headache 
14. Increased hunger 
15. Increased sweating 
16. Nausea 
17. Nervousness 
18. Nightmares 
19. Redness of the face, neck, arms, and occasionally, upper chest 
20. Seizures 
21. Shakiness 
22. Slurred speech 
23. Tightness in the chest 
24. Unusual tiredness or weakness 
25. Foul smelling discharge from the penis 
26. Pain in the skin around the penis 
27. Rash of the penis 
28. Redness, itching, or swelling of the penis 

Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg work by managing blood sugar levels in two ways: metformin and sitagliptin slow sugar production in the liver and boost muscle uptake, while dapagliflozin helps the kidneys flush excess sugar through urine. Together, they cut blood sugar buildup like one shuts the tap and the other opens the drain.

Pregnancy

Due to a lack of studies on the effects of Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg on the fetus during pregnancy, their safety is not clearly established. Therefore, if you are pregnant or planning to conceive, inform your doctor.

Breastfeeding

Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg passes into breast milk. Tell your doctor if you are breastfeeding or plan to breastfeed. Your doctor will advise you if you should stop breastfeeding or stop metformin.

Kidney and Liver Problems

Patients suffering from kidney and liver problems are more prone to kidney and liver damage, as the drug is made into a less toxic form in the liver and kidneys, so consult a doctor before using them.

Avoid alcohol and smoking simultaneously, as they may affect the Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg action and show an effect on blood glucose levels by affecting the liver and pancreas. It can sometimes increase blood sugar levels and sometimes decrease blood sugar levels.

Avoid taking Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Dapagliflozin-(2S,3R,4R,5S,6R) -2- {4-chloro -3-[(4-ethoxyphenyl) methyl] phenyl} -6-(hydroxymethyl) oxane-3,4,5-triol

Metfromin-N, N-dimethylimidodicarbonimidic diamide 

Sitagliptin-(2S)-1-[2-[(3-hydroxyadamantan-1-yl) amino]acetyl] pyrrolidine-2-carbonitrile 

Daily dose

Take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 2500 mg of Dapagliflozin + Metformin + Sitagliptin per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, low blood pressure, unconsciousness, sweating, gastric symptoms, and seizures. Immediately give the patient fruit or glucose-containing liquids and sugary foods to minimize the effects. If you face any of the severe effects, meet the doctor.

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

1. Take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

What are the uses of Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg tablets?

Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets are used to manage blood sugar level in adults with type 2 diabetes, especially when diet and exercise alone are not enough.

How should I take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets?

You should take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets once daily with food to reduce stomach upset. Swallow the tablet whole and do not crush or chew it.

What side effects can occur with Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg tablets?

Common side effects of Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets include genital yeast infections, urinary tract infections, nausea, and increased urination. Rarely, they may cause lactic acidosis or dehydration.

Who should not take Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets? 

Dapagliflozin 10 mg + Metformin 1000 mg + Sitagliptin 100 mg extended-release tablets should not be used by people with severe kidney problems, a history of lactic acidosis, or those who are severely dehydrated.

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