Empagliflozin 12.5 mg + Metformin 1000 mg combination medicines that lower blood sugar in different ways. Metformin reduces blood glucose sugar made by the liver and improves insulin action, while empagliflozin helps to remove excess sugar through urine. Together, they help control diabetes, may aid weight loss, and offer heart and kidney benefits. This medicine can cause stomach upset, especially if taken without and can cause increased urination, urinary tract infections (UTIs), or dehydration, so staying hydrated is key. Avoid consuming alcohol with this to prevent rare lactic acidosis. Taking more than 2500 mg of this combination medicine can cause overdosing effects like low blood sugar, low blood pressure, and unconsciousness.

Empagliflozin 12.5 mg + Metformin 1000 mg is used for the treatment of type 2 diabetes mellitus.

More Common  

1. Abdominal or stomach discomfort 
2. Cough or hoarseness 
3. Decreased appetite 
4. Diarrhea 
5. Fast or shallow breathing 
6. Fever or chills 
7. General feeling of discomfort 
8. Lower back or side pain 
9. Muscle pain or cramping 
10. Painful or difficult urination 
11. Sleepiness 
12. Anxiety 
13. Bladder pain 
14. Bloody or cloudy urine 
15. Blurred vision 
16. Chills 
17. Cold sweats 
18. Confusion 
19. Cool, pale skin 
20. Decreased frequency or amount of urine

Less Common 

1. Anxiety 
2. Blurred vision 
3. Chest discomfort 
4. Cold sweats 
5. Coma 
6. Confusion 
7. Cool, pale skin 
8. Depression 
9. Difficult or labored breathing 
10. Dizziness 
11. Fast, irregular, pounding, or racing heartbeat or pulse 
12. Feeling of warmth 
13. Headache 
14. Increased hunger 
15. Increased sweating 
16. Nausea 
17. Nervousness 
18. Nightmares 
19. Redness of the face, neck, arms, and occasionally, upper chest 
20. Seizures 
21. Shakiness 
22. Slurred speech 
23. Tightness in the chest 
24. Unusual tiredness or weakness 
25. Foul smelling discharge from the penis 
26. Pain in the skin around the penis 
27. Rash of the penis 
28. Redness, itching, or swelling of the penis 

Empagliflozin 12.5 mg + Metformin 1000 mg lower blood sugar in type 2 diabetes from two angles. Metformin slows liver sugar production and boosts muscle uptake, while empagliflozin helps the kidneys flush excess sugar through urine. Together they reduce excess blood sugar.

Pregnancy

Due to a lack of studies on the effects of Empagliflozin 12.5 mg + Metformin 1000 mg on the fetus during pregnancy, its safety is not clearly established. Therefore, if you are pregnant or planning to conceive, inform your doctor.

Breastfeeding

Empagliflozin 12.5 mg + Metformin 1000 mg pass into breast milk. Tell your doctor if you are breastfeeding or plan to breastfeed and they will advise if you should stop breastfeeding or stop Empagliflozin 12.5 mg + Metformin 1000 mg.

Kidney and Liver Problems

Patients suffering from kidney and liver problems are more prone to kidney and liver damage, as the drug is made into a less toxic form in the liver and kidney, so consult a doctor before using them.

Alcohol and smoking can simultaneously affect the drug’s action and show an effect on blood glucose levels by affecting the liver and pancreas. It can sometimes increase blood sugar levels and sometimes decrease blood sugar levels.

Avoid taking Empagliflozin 12.5 mg + Metformin 1000 mg combination with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Empagliflozin- (2S,3R,4R,5S,6R) -2- {4-chloro -3-[(4-ethoxyphenyl) methyl] phenyl} -6-(hydroxymethyl) oxane-3,4,5-triol 

Metformin- N, N-dimethylimidodicarbonimidic diamide

Daily dose

Take Empagliflozin 12.5 mg + Metformin 1000 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 2500 mg of Empagliflozin 12.5 mg + Metformin 1000 mg per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, low blood pressure, unconsciousness, sweating, gastric symptoms, and seizures. Immediately take fruit or glucose-containing liquids and sugary foods to minimize the effects. If you face any of the severe effects, meet the doctor.

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

1. Take Empagliflozin 12.5 mg + Metformin 1000 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Empagliflozin 12.5 mg + Metformin 1000 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Empagliflozin 12.5 mg + Metformin 1000 mg, take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

What are the uses of Empagliflozin 12.5 mg + Metformin 1000 mg tablets?

Empagliflozin 12.5 mg + Metformin 1000 mg tablets are used to manage blood sugar level in adults with type 2 diabetes, especially when diet and exercise alone are not enough.

How should I take Empagliflozin 12.5 mg + Metformin 1000 mg tablets?

You should take Empagliflozin 12.5 mg + Metformin 1000 mg extended-release tablets once daily with food to reduce stomach upset. Swallow the tablet whole and do not crush or chew it.

What side effects can occur with Empagliflozin 12.5 mg + Metformin 1000 mg tablets?

Common side effects of Empagliflozin 12.5 mg + Metformin 1000 mg tablets include genital yeast infections, urinary tract infections, nausea, and increased urination. Rarely, they may cause lactic acidosis or dehydration. 

Who should not take Empagliflozin 12.5 mg + Metformin 1000 mg tablets?

Empagliflozin 12.5 mg + Metformin 1000 mg extended-release tablets should not be used by people with severe kidney problems, a history of lactic acidosis, or those who are severely dehydrated.

Can Empagliflozin 12.5 mg + Metformin 1000 mg tablets cause low blood sugar?

Empagliflozin 12.5 mg + Metformin 1000 mg tablets typically do not cause low blood sugar on their own, but the risk increases if taken with insulin or other diabetes medications. 

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