Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg is an oral combination medicine used to relieve pain, swelling, and inflammation in conditions such as muscle pain, joint pain, back pain, toothache, injury pain, post-surgery pain, and arthritis. Aceclofenac helps reduce pain and inflammation, Paracetamol helps reduce pain and fever, and Serratiopeptidase helps reduce swelling and supports healing.

It is best taken after food to reduce stomach irritation, and alcohol should be avoided because it may increase the risk of stomach problems and liver damage. People allergic to painkillers, stomach ulcer, liver or kidney disease, heart problems, asthma triggered by painkillers, or bleeding disorders should not take this medicine without a doctor’s advice.      

Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg is an oral tablet belonging to the category of pain killer. Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg is used for the following indications:

1. Muscle pain and spams  
2. Back pain 
3. Neck pain 
4. Joint pain 
5. Toothache  
6. Sports injury pain  
7. Post-surgery pain and swelling   

More Common  

1. Nausea 
2. Diarrhea / loose motions 
3. Dizziness 
4. Sometimes vomiting 
5. Stomach upset / indigestion 
6. Increased liver enzymes                   

Less Common 

1. Black stools or blood in stools (possible stomach bleeding) 
2. Vomiting blood 
3. Severe stomach pain 
4. Yellow eyes or yellow skin  
5. Swelling of face, lips, or throat 
6. Breathing difficulty               

This medicine works by reducing pain, inflammation, and swelling through different actions. Aceclofenac blocks the production of pain, swelling and inflammation chemical known as prostaglandins. Paracetamol helps reduce pain and fever by acting on the brain’s pain and temperature control center. Serratiopeptidase is an enzyme that helps break down inflammatory proteins and reduce fluid build-up in swollen tissues, which helps decrease swelling and improves healing. Together, this combination gives better relief in conditions where pain + inflammation + swelling are present. 

Allergy or Hypersensitivity

People allergic to this medicine, or any ingredients of this medication are not recommended to take this medicine as it can cause serious allergic reactions like rash, swelling, or trouble breathing. Always ask your doctor first.

Liver problems

If you have liver disease, consult your doctor before taking this medicine because it can increase the risk of liver damage. Communicate with your doctor about your disease history.

Kidney problems

If you have kidney disease, consult your doctor before taking this medicine because it can worsen kidney function. Communicate with your doctor about your disease history.

Heart problems

 If you have heart disease or high blood pressure, consult your doctor before taking this medicine because it can cause fluid retention and may worsen heart problems. 

Asthma

 If you have asthma, especially after taking painkillers, consult your doctor before taking this medicine because it can trigger breathing problems. Communicate with your doctor about your disease history.

Pregnancy

If you are pregnant, consult your doctor before taking this medicine because it may affect the baby, especially in the later months of pregnancy.

Breastfeeding women

If you are breastfeeding, consult your doctor before taking this medicine because small amounts may pass into breast milk and may affect the baby.

This medicine should be consumed after food to reduce stomach upset. It is best to avoid or limit alcohol while taking this medicine because it can increase drowsiness and may raise the risk of stomach irritation or liver problems. Very heavy or oily meals may also cause more stomach discomfort in some people. 

Avoid taking Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Aceclofenac: 2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid 

Paracetamol – N-acetyl-para-aminophenol (APAP), acetaminophen 

Serratiopeptidase: (11Z)-17-hydroxy-2-phenyl-9-oxa-1,5,14,21-tetrazatetracyclo[12.7.1.0^3,8.0^16,21]docosa-3(8),4,6,11,16,19-hexaene-15,18-dione 

Daily dose

Take Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take this combination more than the prescribed dose by doctor, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children. 

1. Take Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.  

Can paracetamol make you sleepy? 

Yes, paracetamol is made up of acetaminophen, which is responsible for causing drowsiness, a common side effect. 

Can paracetamol cure colds? 

No, paracetamol is used to treat pain and fever. 

How many paracetamols can we take in a day? 

An adult can take up to 2 tablets of 500 mg with a 6-hour gap, up to four times a day. Children aged 10-15 years can take 1 tablet four times a day, with a gap of 4-6 hours between doses.

Can paracetamol delay periods? 

No, there is no side effect of paracetamol that affects the pattern of periods. A delay in periods can occur due to many reasons. 

How much paracetamol can I take when pregnant?  

You can take 500 mg of paracetamol up to four times a day. Paracetamol does not cross the placenta and is not known to cause harm to your fetus. 

Can paracetamol be used for headaches? 

Yes, paracetamol is used to treat headaches. 

What are the side effects of Aceclofenac? 

Common side effects include stomach pain, acidity, nausea, dizziness, headache, and rash. Rarely, it may cause liver or kidney problems, high blood pressure, or gastric bleeding with long-term use.  

What is the usual dose of Aceclofenac per day? 

The typical adult dose is 100 mg twice a day (morning and evening), preferably after meals. Do not exceed 200 mg per day unless advised by your doctor. 

How does Aceclofenac work (mode of action)? 

Aceclofenac works by blocking COX enzymes, especially COX-2, which produce prostaglandins chemicals that cause pain and inflammation. By lowering prostaglandin levels, it helps reduce pain, swelling, and stiffness. 

What are the uses of Serratiopeptidase? 

Serratiopeptidase is used to reduce swelling and pain. It is commonly used for injuries, after surgery, tooth pain, joint pain, muscle pain, and back pain. 

What are the side effects of Serratiopeptidase? 

Common side effects may include stomach upset, nausea, loose motions, and indigestion. Rarely, it may cause allergy like rash, itching, swelling, or breathing trouble.

What is the drug class of Serratiopeptidase? 

Serratiopeptidase is an anti-inflammatory enzyme. It helps reduce swelling and inflammation. 

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