Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule is used to relieve pain, inflammation, and swelling associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, joint pain, and other inflammatory disorders. This medicine consists of active ingredients such as aceclofenac and rabeprazole, where aceclofenac works by blocking the production of certain chemicals (prostaglandins) that cause pain and inflammation, while rabeprazole reduces the production of stomach acid and helps protect the stomach lining from irritation caused by pain-relieving medicines. 

The dose should be taken exactly as prescribed by a doctor. Do not take more than the recommended dose or use it for longer than advised. 

Common side effects include stomach pain, nausea, indigestion, diarrhea, dizziness, headache, and bloating. In rare cases, it may cause stomach ulcers, gastrointestinal bleeding, severe allergic reactions, liver problems, or kidney problems that require immediate medical attention. 

Taking more than the recommended dose may increase the risk of severe stomach pain, nausea, vomiting, stomach bleeding, dizziness, drowsiness, liver damage, or kidney damage. Seek immediate medical attention if overdose symptoms occur.      

Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule is used to treat the following conditions: 

1. Osteoarthritis 
2. Rheumatoid arthritis 
3. Ankylosing spondylitis 
4. Joint pain and inflammation 
5. Muscle pain and inflammatory conditions                    

More Common

1. Stomach pain 
2. Nausea 
3. Indigestion 
4. Diarrhea 
5. Headache 
6. Dizziness 
7. Bloating              

Less Common 

1. Stomach ulcer 
2. Gastrointestinal bleeding 
3. Liver function abnormalities 
4. Kidney problems 
5. Severe allergic reactions 
6. Skin rash 
7. Swelling of face or throat          

This medicine consists of active ingredients such as aceclofenac (sustained release) 200 mg and rabeprazole (enteric coated) 20 mg that work together to relieve pain and protect the stomach. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation by blocking prostaglandin production. Rabeprazole is a proton pump inhibitor (PPI) that decreases stomach acid production and helps protect the stomach lining from irritation and ulcers that may occur with NSAID use.

Allergy/Hypersentivity

If you are allergic to aceclofenac, rabeprazole, other NSAIDs, or proton pump inhibitors, avoid using this medicine. Serious allergic reactions such as rash, itching, swelling, or breathing difficulty may occur.

Stomach Disorders

If you have a history of stomach ulcers, gastrointestinal bleeding, or inflammatory bowel disease, aceclofenac may worsen these conditions. Always communicate with your doctor about your past disease history for your safety. 

Kidney or Liver Disease

Patients with liver or kidney problems may require dose adjustments. Consult your doctor before taking this medicine.

Heart Disease

Use cautiously in patients with heart disease, high blood pressure, or fluid retention, as NSAIDs may increase cardiovascular risks.

Avoid excessive alcohol consumption as it may increase the risk of stomach irritation, ulcers, and bleeding. 

Avoid taking Aceclofenac (sr) 200mg + Rabeprazole (ec) 20mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Aceclofenac: 2-[2-[2-[(2,6-dichlorophenyl) amino]phenyl]acetyl]oxyacetic acid

Rabeprazole: 2-[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methylsulfinyl]-1H-benzimidazole 

Daily dose

Take Aceclofenac (sr) 200mg + Rabeprazole (ec) 20mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than the prescribed dose of Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg. Overdose may cause severe stomach pain, nausea, vomiting, dizziness, drowsiness, stomach bleeding, kidney problems, or liver damage. Seek immediate medical attention if overdose symptoms occur.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

1. Take Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

What are the uses of Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule? 

Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule are used to relieve pain, inflammation, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, joint pain, and muscle pain. Rabeprazole helps protect the stomach from irritation caused by Aceclofenac. 

What are the side effects of Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule? 

Common side effects of Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule include stomach pain, nausea, indigestion, diarrhea, bloating, headache, and dizziness. Rarely, it may cause stomach ulcers, gastrointestinal bleeding, liver problems, kidney problems, or allergic reactions.

What are the contraindications of Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule? 

Aceclofenac (SR) 200 mg + Rabeprazole (EC) 20 mg capsule should not be used in people who are allergic to Aceclofenac, Rabeprazole, other NSAIDs, or proton pump inhibitors. It is also contraindicated in patients with active stomach ulcers, gastrointestinal bleeding, severe liver disease, severe kidney disease, or a history of severe allergic reactions to similar medicines. Always follow your doctor’s instructions and do not self-medicate with this medicine.  

1. Rabeprazole (Oral Route) Description and Brand Names – Mayo Clinic [Internet].  Available from 
2. Rabeprazole: MedlinePlus Drug Information [Internet]. medlineplus.gov. Available from 
3. PubChem. Aceclofenac [Internet]. pubchem.ncbi.nlm.nih.gov. Available from 
4. Aceclofenac [Internet]. go.drugbank.com. Available from