This medicine contains diclofenac, paracetamol, and chlorzoxazone. This medicine is used to relieve pain, inflammation, swelling, and muscle spasms associated with conditions such as back pain, neck pain, muscle strain, sprains, sports injuries, joint pain, and painful musculoskeletal disorders.  

Diclofenac reduces pain and inflammation; paracetamol helps relieve pain and fever, while chlorzoxazone relaxes tight and painful muscles. Together, they provide effective relief from pain along with muscle relaxation.  

It is best taken with or after food to reduce stomach irritation. Avoid alcohol while taking this medicine because it may increase drowsiness, stomach bleeding, and liver damage. People with stomach ulcers, severe liver or kidney disease, heart disease, allergy to painkillers, muscle disorders, or breathing problems should consult their doctor before using this medicine. 

Diclofenac 50 mg + Paracetamol 325 mg + Chlorzoxazone 500 mg tablet is used to treat the following conditions: 

1. Muscle pain and spasms  
2. Back pain and Neck pain  
3. Joint pain  
4. Sprains and strains  
5. Sports injury pain  
6. Painful muscle stiffness  
7. Post-surgery pain with muscle spasms      

More Common

1. Severe stomach pain  
2. Black stools or blood in stools  
3. Vomiting blood  
4. Yellow eyes or yellow skin (possible liver problem)  
5. Difficulty breathing  
6. Swelling of face, lips, or throat  
7. Severe allergic skin rash  
8. Extreme drowsiness or confusion    

Less Common 

1. Nausea  
2. Vomiting  
3. Stomach upset  
4. Heartburn  
5. Dizziness  
6. Sleepiness  
7. Weakness  
8. Loss of appetite 

This medicine contains ingredients like diclofenac, paracetamol, and chlorzoxazone. Diclofenac blocks the production of prostaglandins, which cause pain and inflammation. Paracetamol reduces pain and fever by acting on the brain’s pain and temperature control center. Chlorzoxazone acts on the central nervous system to relax tight muscles and reduce painful muscle spasms. Together, they provide effective relief from pain, inflammation, and muscle stiffness. 

Allergy or Hypersensitivity

People who are allergic to diclofenac, paracetamol, chlorzoxazone, or any other ingredient of this medicine should not take it without consulting a doctor, as it may cause severe allergic reactions.

Liver Problems

Consult your doctor before taking this medicine if you have liver disease because both paracetamol and chlorzoxazone may increase the risk of liver damage.

Kidney Problems

People with kidney disease should consult their doctor before using this medicine because diclofenac may worsen kidney function.

Heart Problems

If you have heart disease or high blood pressure, consult your doctor before taking this medicine because diclofenac may increase the risk of heart-related complications.

Stomach Ulcer or Bleeding

People with stomach ulcers or a history of stomach bleeding should use this medicine only under medical supervision because diclofenac can increase the risk of bleeding.

Asthma

People who have asthma triggered by painkillers should consult their doctor before taking this medicine because it may worsen breathing problems.

Pregnancy

Consult with your doctor before taking this medicine during pregnancy. It is generally not recommended during the last three months of pregnancy.

Breastfeeding

Consult your doctor before taking this medicine while breastfeeding because small amounts of the medicine may pass into breast milk.

Take this medicine after food to reduce stomach irritation. Avoid alcohol because it can increase drowsiness, stomach bleeding, and liver damage. Heavy or oily meals may increase stomach discomfort in some people. 

Avoid taking this medicine with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Diclofenac: 2-[2-(2,6-dichloroanilino) phenyl]acetic acid 

Paracetamol – N-acetyl-para-aminophenol (APAP), acetaminophen 

Chlorzoxazone: 5-chloro-3H-1,3-benzoxazol-2-one 

Daily dose

Take this medicine exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

 If you forget to take this medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

Taking more than the prescribed dose may cause severe drowsiness, nausea, vomiting, stomach bleeding, liver damage, confusion, difficulty breathing, or unconsciousness. Seek immediate medical attention if an overdose is suspected.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

1. Take this medicine exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking this medicine without your doctor’s approval, even if you feel better. 
3. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.    

What are the uses of Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet? 

Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet is used to treat muscle pain, muscle spasms, back pain, neck pain, joint pain, sprains, strains, sports injuries, and painful muscle stiffness. It helps reduce pain, inflammation, and relaxes tight muscles. 

Can I take Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet after food? 

Yes. It is recommended to take this medicine after food to reduce the risk of stomach irritation and acidity. Follow your doctor’s instructions regarding the dose.

Does Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet cause drowsiness? 

Yes. Chlorzoxazone may cause drowsiness, dizziness, or sleepiness in some people. Avoid driving or operating heavy machinery until you know how the medicine affects you. 

Can I drink alcohol while drinking Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet? 

No. Alcohol should be avoided while taking this medicine because it can increase drowsiness and raise the risk of stomach bleeding and liver damage.

How long should I take Diclofenac 50 mg, Paracetamol 325 mg, Chlorzoxazone 500 mg tablet? 

Take this medicine only for the duration prescribed by your doctor. Do not continue using it for longer than recommended, as prolonged use may increase the risk of side effects such as stomach, liver, or kidney problems. 

1. Drugs.com. Paracetamol [Internet]. 2024 [cited 2024 Nov 28]. Available from 
2. Diclofenac (Oral Route) Description and Brand Names – Mayo Clinic [Internet]. Available from 
3. Alfaro RA, Modi PV. Diclofenac [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from 
4. NHS. About paracetamol for adults [Internet]. nhs.uk. 2022. Available from 
5. PubChem. Chlorzoxazone [Internet]. Nih.gov. PubChem; 2026. Available from 
6. PubChem. Diclofenac [Internet]. @pubchem. PubChem; 2020. Available from