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Ofloxacin 200 mg + Ornidazole 500 mg is a combination medicine used to treat infections caused by bacteria and certain protozoa. It is used for urinary tract infections, stomach and intestinal infections like diarrhea or dysentery, respiratory infections like bronchitis and pneumonia, vaginal or reproductive tract infections, skin infections, dental infections, post-surgical infections, and some eye or ear infections. Ofloxacin works by stopping bacteria from multiplying and repairing themselves, while Ornidazole damages the DNA of bacteria and protozoa, which kills the germs and clears the infection.
Common side effects include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, and metallic taste, while rare but serious effects may include allergic reactions, tendon pain, numbness, mood changes, or irregular heartbeat. This medicine should be used with caution in pregnancy, kidney or liver problems, and in people allergic to either drug. It should be taken with water, avoiding milk, dairy, iron, or antacids at the same time, and medical help should be sought immediately in case of overdose or serious side effects.
| Uses | 1. To treat gastrointestinal infections, such as acute diarrhea, dysentery, and food poisoning. 2. To treat urinary tract infections (UTIs). 3. To treat respiratory tract infections, including bronchitis and pneumonia. 4. To treat reproductive tract infections (e.g., bacterial vaginosis, pelvic inflammatory disease). 5. To treat skin and soft tissue infections, such as infected wounds or abscesses. 6. To treat dental infections, including gum and tooth abscesses. 7. To treat post-surgical infections 8. To treat eye and ear infections. |
| Common Side Effects | 1. Nausea or vomiting 2. Diarrhea or loose stools 3. Stomach pain or upset stomach 4. Headache 5. Dizziness 6. Metallic taste in the mouth |
| Additional Information | This medicine should only be used under medical supervision. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water |
Ofloxacin 200 mg + Ornidazole 500 mg is a combination antibiotic medicine used to kill bacteria and certain germs, and treat infections such as:
This medicine works by killing the germs that cause infections. Ofloxacin, stops bacteria from multiplying, while Ornidazole damages the DNA of certain bacteria and protozoa. Together, they treat infections in the stomach, urinary tract, reproductive organs, skin, teeth, and respiratory system.
Do not take this medicine if you are allergic to ofloxacin, ornidazole, or other similar antibiotics. It may cause severe allergic reactions like rash, swelling, or difficulty breathing. Always inform your doctor about any past drug allergies.
Avoid if you have had tendon pain or rupture, especially from previous antibiotic use. This medicine may increase the risk of tendon injury. Communicate with your doctor about your past illness
Use with caution if you have serious kidney or liver disease, as the medicine may build up in the body and cause side effects. Tell your doctor about any such conditions.
This medicine should be avoided during pregnancy or breastfeeding unless prescribed by a doctor, as it may affect the baby. Always inform your doctor if you are pregnant or breastfeeding.
Ofloxacin 200 mg + Ornidazole 500 mg can be taken with or without food, but you should avoid taking it with milk, yogurt, cheese, or other calcium-rich foods, as these can reduce how well the medicine is absorbed. Also, avoid taking it at the same time as iron, zinc, or antacid tablets, because they can block the medicine from working properly.
Avoid taking Ofloxacin 200 mg + Ornidazole 500 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Ofloxacin: 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0] trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Ornidazole: 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol

Take Ofloxacin 200 mg + Ornidazole 500 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
It is not recommended to take more than the prescribed dose of Ofloxacin 200 mg + Ornidazole 500 mg. Overdose may cause nausea, vomiting, stomach pain, dizziness, headache, fast or irregular heartbeat, nervousness, or muscle cramps. In case of any of these symptoms, seek immediate medical help.
Ofloxacin 200 mg + Ornidazole 500 mg Tablets are used to treat infections caused by bacteria and certain germs. They help with urinary tract infections, stomach or intestinal infections like diarrhea and dysentery, respiratory infections like bronchitis and pneumonia, vaginal infections, skin infections, dental infections, post-surgery infections, and some eye or ear infections.
These tablets may cause nausea, vomiting, diarrhea, stomach pain, headache, dizziness, or a metallic taste in the mouth. Rarely, they can cause severe allergic reactions, tendon pain or rupture, numbness or tingling in the hands or feet, severe diarrhea from gut infection, mood changes, confusion, or irregular heartbeat. If any serious symptoms occur, seek medical help immediately.
Ofloxacin may cause nausea, vomiting, diarrhea, stomach pain, headache, dizziness, or a metallic taste in the mouth. Rarely, it can cause severe allergic reactions, tendon pain or rupture, numbness or tingling in the hands or feet, mood changes, confusion, or irregular heartbeat. If any serious symptoms occur, seek medical help immediately.
Ofloxacin is an antibiotic that kills bacteria by stopping them from multiplying and repairing themselves. This prevents the bacteria from growing and allows the body to fight off the infection.
Ofloxacin is generally not recommended during pregnancy because it may affect the baby’s bone and joint development. It should only be taken if a doctor decides the benefits outweigh the risks. Always inform your doctor if you are pregnant before taking this medicine.
Ornidazole may cause nausea, vomiting, stomach pain, diarrhea, or a metallic taste in the mouth. Some people may feel dizzy, sleepy, or have headache. Rarely, it can cause allergic reactions, numbness or tingling in the hands or feet, or mood changes. If any severe symptoms occur, seek medical help immediately.
The usual adult dose of Ornidazole tablets is 500 mg twice a day or as prescribed by your doctor.
Ornidazole belongs to the nitroimidazole class of anti-infective drugs and works against certain bacteria and protozoa.
Ornidazole gel is used for gum infections, mouth ulcers, or dental abscesses. It helps kill bacteria in the mouth, reduce infection, swelling, and pain, and promotes healing.
Ornidazole works by entering the germs (bacteria and protozoa) and damaging their DNA, which stops them from growing and multiplying. As a result, the germs die, and the infection gets treated.


Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 06 Jul 2026
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