Ofloxacin 200 mg is an oral antibiotic from the fluoroquinolone category used to treat bacterial infections such as urinary tract infections, respiratory infections like bronchitis and pneumonia, skin and soft-tissue infections, sexually transmitted infections like chlamydia and gonorrhea, and gastrointestinal infections including typhoid. It works by blocking a bacterial enzyme called DNA gyrase, stopping bacteria from multiplying and allowing the body to fight the infection. Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, and dizziness, while rare but serious effects can include allergic reactions, tendon pain or rupture, nerve problems, irregular heartbeat, and liver issues.  

Ofloxacin 200 mg should not be taken by people allergic to it, children and teens, pregnant or breastfeeding women, or those with tendon, kidney, or liver problems. It can be taken with or without food, but dairy products, calcium-fortified juices, antacids, and supplements containing iron, magnesium, or zinc should be avoided at the same time as they can reduce the medicine’s effectiveness. 

Ofloxacin 200 mg is used to prevent and treat conditions like: 

1. Urinary tract infections (UTIs) 
2. Respiratory tract infections (like bronchitis or pneumonia) 
3. Skin and soft-tissue infections 
4. Sexually transmitted infections (like chlamydia or gonorrhea) 
5. Gastrointestinal infections (like typhoid or bacterial diarrhea)    

1. Take Ofloxacin 200 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Ofloxacin 200 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take Ofloxacin 200 mg, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

More Common  

1. Nausea 
2. Vomiting 
3. Diarrhea 
4. Stomach pain 
5. Headache 
6. Dizziness   

Less Common

1. Allergic reactions (rash, swelling, breathing difficulty) 
2. Hearing problems  
3. Irregular heartbeat (QT prolongation) 
4. Severe diarrhea due to C. difficile 
5. Liver problems (yellowing of skin/eyes, dark urine)   

Ofloxacin 200 mg works by killing the bacteria causing the infection. It does this by blocking an enzyme called DNA gyrase that bacteria need to copy their DNA. Without this enzyme, the bacteria cannot multiply or repair themselves, so they die, allowing your body to fight off the infection and heal. 

Allergy or hypersensitivity

If you are allergic to Ofloxacin 200 mg or other fluoroquinolone antibiotics, taking it can cause serious reactions like rashes, swelling, or trouble breathing. Stop the medicine immediately and get medical help. 

Children

Children under 18 years old, are usually not recommended to take this medicine because it may affect growing bones and joints. Your doctor will suggest a safer alternative. 

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, Ofloxacin 200 mg can harm the baby or infant. Avoid taking it unless your doctor specifically allows it. 

Tendon or Muscle Problems

If you have had tendon problems before, taking Ofloxacin 200 mg can increase the risk of tendon pain or rupture. Tell your doctor first. 

Kidney or Liver Issues

If you have severe kidney or liver problems, Ofloxacin 200 mg may not be safe as it is processed by these organs. Your doctor may need to adjust the dose or choose another antibiotic. 

Ofloxacin 200 mg can be taken with or without food but taking it after a meal may help reduce stomach upset. You should avoid taking it at the same time as dairy products, calcium-fortified juices, antacids, or supplements containing iron, magnesium, or zinc, as these can reduce how well the medicine works. Other common foods or drinks usually do not interfere with Ofloxacin. 

Avoid taking Ofloxacin 200 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Ofloxacin IUPAC Name: 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid 

Daily dose

Take Ofloxacin 200 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

 It is not recommended to take more than 800 mg ofloxacin per day, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat. 

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

What are the uses of Ofloxacin 200 mg? 

Ofloxacin 200 mg tablet is used to treat bacterial infections such as urinary tract infections, respiratory infections (like bronchitis or pneumonia), skin and soft-tissue infections, sexually transmitted infections (like chlamydia or gonorrhea), and gastrointestinal infections like typhoid or bacterial diarrhea. 

What are the side effects of Ofloxacin 200 mg? 

Common side effects of Ofloxacin 200 mg include nausea, vomiting, diarrhea, stomach pain, headache, and dizziness. Rare but serious side effects can include allergic reactions (rash, swelling, difficulty breathing), tendon pain or rupture, nerve problems (tingling or numbness), irregular heartbeat, and liver problems (yellowing of skin/eyes, dark urine). 

Can Ofloxacin 200 mg be taken during pregnancy? 

Ofloxacin 200 mg is not recommended during pregnancy because it may harm the developing baby. It should only be taken if a doctor specifically prescribes it after weighing the benefits and risks. 

1. Ofloxacin 200 mg tablet: Uses, Side Effects, Price | Generic | SayaCare [Internet]. Sayacare.in. 2025 [cited 2025 Dec 9]. Available from 
2. Ofloxacin [Internet]. go.drugbank.com. Available from 
3. Graham DB, Tripp J. Ofloxacin [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2021. Available from 
4. PubChem. Ofloxacin [Internet]. pubchem.ncbi.nlm.nih.gov. Available from