Aspirin 75 mg + Clopidogrel 75 mg (EC) tablet consists of 2 ingredients that work by breaking cholesterol and blood fats. Common side effects of this medication include tiredness, stomach upset, or muscle pain and, rarely, serious muscle damage. It’s not safe for those with liver, kidney, or gallbladder issues, during pregnancy, and if they’ve had bad reactions to similar drugs. Avoid alcohol and take vitamin K-rich foods with care because it can increase the drug effects and can cause internal bleeding. Take this medication after food to get the maximum effect. Taking more than 200 mg of this medication per day can cause internal bleeding, liver and kidney damage, sweat, and dizziness.

Aspirin 75 mg + clopidogrel 75 mg is used to treat following conditions: 

1. Increased levels of bad cholesterol (hypercholesterolemia) 
2. Clogged fat in arteries (atherosclerosis) 
3. Clots in blood vessels

More Common

1. Chills  
2. Fever  
3. Itching, skin rash  
4. Muscle aches and pains  
5. Nausea  
6. Stomach pain  
7. Vomiting  
8. Runny nose, sneezing; or 
9. Difficulty in moving 
10. Joint pain or swelling 
11. Muscle pain, cramps, spasms, or stiffness 

Less Common 

1. Sharp stomach pain spreading to your back or shoulder blade 
2. Loss of appetite, stomach pain just after eating a meal 
3. Jaundice (yellowing of the skin or eyes) 
4. Fever, chills, weakness, sore throat, mouth sores, unusual bruising or bleeding 
5. Chest pain, sudden cough, wheezing, rapid breathing, coughing up blood 
6. Swelling, warmth, or redness in an arm or leg 
7. Blurred vision 
8. Chest pain, discomfort, tightness, or heaviness 
9. Difficult, burning, or painful urination 
10. Dry mouth 
11. Fast, irregular, pounding, or racing heartbeat or pulse 
12. Flushed, dry skin 
13. Fruit-like breath odor 
14. Increased hunger 
15. Increased thirst 
16. Increased urination 
17. Loss of consciousness 
18. Muscle tension or tightness 
19. Nausea 
20. Slow heartbeat 
21. Stomachache 
22. Sweating 
23. Trouble breathing 
24. Unexplained weight loss 
25. Unusual tiredness or weakness 
26. Vomiting 

This medicine works by cleaning the cholesterol stacked in the blood vessel and reducing the production of bad cholesterol in the body.

Pregnancy

This medicine can harm a developing fetus, with animal studies showing growth issues, and due to limited human data, it’s avoided in pregnancy. Always inform your doctor before using this medication.

Breastfeeding

Aspirin 75 mg + clopidogrel 75 mg can pass through breast milk and can harm your baby. It’s best to consult a doctor before consuming the medication.

Kidney and Liver Problems

Aspirin 75 mg + clopidogrel 75 mg can affect the liver’s functioning by causing changes in liver enzymes and can lead to severe toxicity and liver damage. So, inform your doctor before taking this medication.

Alcohol and smoking can interact with the medicine, simultaneously affecting the drug’s action, and can cause an increase or decrease in the drug’s action.

Avoid taking Aspirin 75 mg + Clopidogrel 75 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Aspirin- 2-acetyloxybenzoic acid

Clopidogrel- Methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate

Daily dose

Take aspirin 75 mg + clopidogrel 75 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 200 mg of this medicine per day, as it may cause severe overdosing effects like liver damage, kidney damage, pancreatitis, muscle problems, nausea, and muscle problems. If you face any of the severe effects, consult the doctor.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

1. Take aspirin 75 mg + clopidogrel 75 mg exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking aspirin 75 mg + clopidogrel 75 mg without your doctor’s approval, even if you feel better. 
3. If you forget to take aspirin 75 mg + clopidogrel 75 mg, take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

What are the uses of the aspirin 75 mg + clopidogrel 75 mg combination medicine?

Aspirin 75 mg + clopidogrel 75 mg is an oral medicine belonging to the category of lipid-lowering drugs and is used for the treatment of Increased levels of bad cholesterol (hypercholesterolemia) and Clogged fat in arteries (atherosclerosis).

What is the price of aspirin 75 mg + clopidogrel 75 mg tablets?

At Saya Care, aspirin 75 mg + clopidogrel 75 mg costs 50 rupees for 20 tablets. They are used to control fat and cholesterol in the body and to improve heart health.

What are the side effects of aspirin 75 mg + clopidogrel 75 mg?

Aspirin 75 mg + clopidogrel 75 mg are medicines that work together to lower harmful cholesterol and blood fats. This may cause side effects like tiredness, stomach upset, or muscle pain and, rarely, serious muscle damage.

1. The Health Site. How to lower cholesterol in one week: 10 Indian foods to lower cholesterol naturally at home. TheHealthSite.com. 2024 [cited 2024 Nov 2]. Available from. 
2. Hoogwerf BJ. Statins may increase diabetes, but benefit still outweighs risk. Cleveland Clinic Journal of Medicine. 2023 Jan 3;90(1):53-62. Available from. 
3. National Center for Biotechnology Information (2026). PubChem Compound Summary for CID 2244, Aspirin. Retrieved March 26, 2026 Available from. 
4. Drugs.com. Aspirin: Uses, Dosage, Side Effects & Interactions [Internet]. Drugs.com; 2024 Mar 1 [cited 2026 Mar 26]. Available from. 
5. Johnston B, Ishver A. Aspirin (Bayer, Vazalore, and others): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing [Internet]. WebMD; 2025 Apr 28 [cited 2026 Mar 26]. Available from. 
6. Drugs.com. Clopidogrel [Internet]. Drugs.com; 2024 [cited 2025 Jul 16]. Available from. 
7. Drugs.com. Clopidogrel: Uses, Side Effects & Warnings [Internet]. Drugs.com; 2025 Mar 21 [cited 2026 Mar 26]. Available from. 
8. Mayo Clinic. Clopidogrel (oral route) – Side effects & dosage [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; 2026 Mar 01 [cited 2026 Mar 26]. Available from.