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Amlodipine 5 mg + Metoprolol (pr) 50 mg

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Amlodipine 5 mg + Metoprolol (pr) 50 mg

Rx Required

Drug Code: 123

Rx Required
| tablettablet| Pack of 10 tablets
MRP ₹61

₹28

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Batch Details

Composition

amlodipine 5 mg + metoprolol (pr) 50 mg

Batch

51|VRO26001

Expiry

January 2028

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Batch Details

Composition

amlodipine 5 mg + metoprolol (pr) 50 mg

Batch

51|VRO26001

Expiry

January 2028

About Amlodipine 5 mg + Metoprolol 50 mg (ER)

Amlodipine 5 mg + Metoprolol 50 mg (er) tablet is used to treat high blood pressure and chest pain due to poor blood flow to the heart. It works by relaxing blood vessels and improving circulation, which eases the heart’s workload. Common side effects include headaches, dizziness, swollen ankles, and sometimes tummy discomfort or skin rashes. People with serious liver problems, very low blood pressure, or heart issues, or women who are pregnant or breastfeeding, should inform their doctor before using it. Drinking grapefruit juice with this medication makes it stronger and increases side effects, so it’s best skipped. Always store this medicine in a cool, dry place away from sunlight, and keep it in its original packaging. Taking more than 100 mg of this medicine daily can cause overdosing effects like severe hypotension, dizziness, fainting, and potentially life-threatening cardiovascular collapse.

Medicine Highlights

Uses 1. To treat high blood pressure 
2. To prevent heart attacks. 
Common Side Effects  1. Headache 
2. Dizziness 
3. Constipation 
4. Skin rash 
5. Decreased blood pressure 
6. Nausea 
Additional Information 1. Take medicine every day at the same time to maintain the drug well in the blood. 
2. Do not stop the medicine usage suddenly 
Storage 1. The medicine should be stored at room temperature.  
2. Keep away from sunlight and moisture.  
3. Keep away from the reach of children 
How to Take This MedicineTake this medicine orally with a sip of water

Amlodipine 5 mg + Metoprolol 50 mg (ER) Uses

Amlodipine 5 mg + Metoprolol 50 mg is an oral medicine belonging to the category of antihypertensives. Amlodipine 5 mg + Metoprolol 50 mg is used to prevent high blood pressure and heart attacks.

Amlodipine 5 mg + Metoprolol 50 mg (ER) side effects

More Common

  1. Headache 
  2. Dizziness 
  3. Constipation 
  4. Skin rash 
  5. Decreased blood pressure 
  6. Nausea 

Less Common 

  1. Lightheadedness 
  2. Palpitations 
  3. Oedema (accumulation of water in the tissues) 

How Amlodipine 5 mg + Metoprolol 50 mg (ER) works

Amlodipine 5 mg + Metoprolol 50 mg (ER) is a combination of Amlodipine and Metoprolol. Here Amlodipine relaxes and widens blood vessels, making it easier for blood to flow and lowering pressure. Metoprolol slows down the heart rate and reduces the force of pumping, easing strain on the heart. Together, they help control high blood pressure and protect the heart from overwork.

Safety Measures and Warning

Pregnancy

Pregnant women are not recommended to take Amlodipine 5 mg + Metoprolol 50 mg, as there are no human studies supporting its safety during pregnancy. In case of an emergency, consult a doctor before using it.

Breastfeeding

Amlodipine 5 mg + Metoprolol 50 mg can pass into breast milk, so it’s used with caution during breastfeeding. Other safer options are usually tried first. If it is needed, the baby should be watched closely for any changes like diarrhea or sleepiness. Always talk to your doctor before using it.

Kidney and Liver Problems

Patients suffering from kidney and liver problems are more prone to kidney and liver damage, as the medicine is converted into a less toxic form in the liver and excreted through the kidney. They may cause interactions and cause severe toxicity, so consult a doctor before using it.

Amlodipine 5 mg + Metoprolol 50 mg (ER) Interaction with Food Product

Amlodipine 5 mg + Metoprolol 50 mg is generally safe with food, and it is recommended to avoid alcohol and smoking with Amlodipine 5 mg + Metoprolol 50 mg , as they can alter the drug’s effect and may cause severe drowsiness and sedation because of their direct action on the brain.

Amlodipine 5 mg + Metoprolol 50 mg (ER) Interaction with Other Medicines

Avoid taking Amlodipine 5 mg + Metoprolol 50 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Amlodipine 5 mg + Metoprolol 50 mg (ER) Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Amlodipine- 3-O-(1-benzhydrylazetidin-3-yl) 5-O-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Amlodipine 5 mg + Metoprolol 50 mg (PR)

Metoprolol-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

Amlodipine 5 mg + Metoprolol 50 mg (PR)

Intake routine/cycle

Daily dose

Take Amlodipine 5 mg + Metoprolol 50 mg (ER) exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 600 mg of Amlodipine+ Metoprolol per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.

Storage

  1. Store the medicine at room temperature. 
  2. Keep away from sunlight and moisture. 
  3. Keep out of reach of children 

Directions for use

  1. Take Amlodipine 5 mg + Metoprolol 50 mg (ER) exactly as prescribed by your doctor, at the same time each day. 
  2. Do not stop taking Amlodipine 5 mg + Metoprolol 50 mg (ER) without your doctor’s approval, even if you feel better. 
  3. If you forget to take Amlodipine 5 mg + Metoprolol 50 mg (ER), take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

FAQ’s

What is the mechanism of action of Amlodipine 5 mg + Metoprolol 50 mg?

Amlodipine 5 mg + Metoprolol 50 mg (ER) is a combination of Amlodipine and Metoprolol. Here Amlodipine relaxes and widens blood vessels, making it easier for blood to flow and lowering pressure. Metoprolol slows down the heart rate and reduces the force of pumping, easing strain on the heart. Together, they help control high blood pressure and protect the heart from overwork.

What are the uses of Amlodipine and metoprolol tablets?

Amlodipine 5 mg + Metoprolol 50 mg are medicines used to treat high blood pressure and chest pain due to poor blood flow to the heart. It helps by relaxing blood vessels and improving circulation, which eases the heart’s workload.

What are the side effects of the Amlodipine 5 mg + Metoprolol 50 mg tablets?

Common side effects of Amlodipine 5 mg + Metoprolol 50 mg use include headaches, dizziness, swollen ankles, and sometimes tummy discomfort or skin rashes.

Reference

  1. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 5282138, Amlodipine; [cited 2026 Mar. 19]. Available from. 
  2. Kadian R, Nanda A. A Comprehensive Insight on Pharmacological Properties of Amlodipine: A Fourth-generation Calcium Channel Blocker. Cardiovasc Hematol Agents Med Chem. 2023;22(1):40-50.Available from. 
  3. Zhang Y, Li H, Chen X, Wang J, Liu Q. Deep learning-based prediction of cardiovascular outcomes using multimodal data. J Transl Med AI. Available from. 
  4. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 65999, Metoprolol; [cited 2026 Apr. 13]. Available from. 
Siva Krishna Adithya Bhumireddy avatar

Written By-

Siva Krishna Adithya Bhumireddy

Medical content writer

Bachelors in Pharmacy | 1+ Year experience

Mahak Phartyal avatar

Reviewed By-

Mahak Phartyal

Medical Content writer and reviewer

Bachelors in Pharmacy | 3+ Year experience

Last Updated: 12 Jul 2026

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