Ambroxol 60 mg + Levocetirizine 5 mg are a combination of mucolytics and antihisatimes and are used for treatment of 

1. Throat irritation, sneezing, and runny nose caused by allergies triggered by dust or pet hairs and itchy or watery eyes (hay fever).  
2. Wet cough 
3. Mucus clearance. 

More Common  

1. Sleepiness or feeling drowsy 
2. Tiredness or weakness 
3. Dry mouth 
4. Headache 
5. Feeling dizzy 

Less Common 

1. Upset stomach or nausea 
2. Sore throat 
3. Nosebleed 
4. Fast heartbeat 
5. Trouble sleeping 
6. Weight gain 
7. Allergic reaction (swelling, rash, itching) 

Ambroxol helps loosen and clear thick mucus from the lungs, making coughs less effective and breathing easier. Levocetirizine calms allergy reactions by blocking the body’s histamine response, reducing sneezing, itching, and stuffy nose.

Allergy

Individuals with a known hypersensitivity or allergy to levocetirizine, cetirizine, or any ingredients in the formulation should avoid the drug because it may trigger severe allergic reactions

Kidney Disease

This medicine is removed through the kidneys, and weak kidneys can’t clear it properly, which can lead to side effects.

Infants and Young Children

Children under the age of 6 months should not use levocetirizine, and special caution is required for children up to 11 years old with pre-existing kidney issues due to increased risk of side effects.

Avoid consuming caffeinated foods, as they can cause side effects like allergies and skin rashes. Alcohol and smoking can increase the medicine’s side effects occurring and worsen the patient’s conditions.

Avoid taking levocetirizine with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Ambroxol- 4-[(2-amino-3,5-dibromophenyl) methylamino] cyclohexan-1-ol; hydrochloride

Levocetirizine- 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl] piperazin-1-yl]ethox acetic acid

Daily dose

Take Ambroxol + Levocetirizine exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

Do not take more than 100 mg of this medicine a day, as the dose increases the risk of serious overdosing effects such as drowsiness, confusion, agitation, and dizziness. If you know someone who takes this medicine and has these symptoms, then rush them to the hospital immediately.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children. 

1. Take Ambroxol + Levocetirizine exactly as prescribed by your doctor at the same time each day. 
2. Do not stop taking Ambroxol + Levocetirizine without your doctor’s approval, even if you feel better. 
3. If you forget to take Ambroxol + Levocetirizine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Ambroxol 60 mg + levocetirizine 5 mg is a combination medicine where ambroxol (a mucolytic drug) thins and clears mucus from the lungs, and levocetirizine (an antihistamine) reduces allergy symptoms. It is commonly prescribed for coughing with mucus, allergic rhinitis, bronchitis, and breathing discomfort. Common side effects of this medicine include drowsiness, headaches, dry mouth, stomach upset, nausea, or diarrhea. Food does not interact with this medication, but taking it with alcohol can worsen drowsiness and stomach irritation. People with severe liver or kidney disease, stomach ulcers, or those who need to stay alert (like drivers) should avoid it. Taking more than 100 mg of this medicine can cause extreme sleepiness, confusion, stomach upset, or low blood pressure, and medical help is required immediately.

What are the uses of ambroxol and levocetirizine combination medicine?

The combination of ambroxol and levocetirizine is mainly used to treat cough with mucus and allergy-related breathing problems. It helps clear mucus from the lungs while also reducing sneezing, itching, and nasal congestion caused by allergies.

What are the drug-drug interactions of ambroxol and levocetrizine tablets?

Ambroxol can interact with antibiotics by increasing their penetration into lung tissue, while levocetirizine may cause extra drowsiness if combined with sedatives, alcohol, or other antihistamines. Together, caution is needed with drugs affecting the liver or kidneys, as side effects like sleepiness, stomach upset, or reduced alertness may become stronger.

What are the side effects of ambroxol tablet?

Common side effects of ambroxol tablets include nausea, vomiting, stomach upset, diarrhea, and mild allergic reactions like rash or itching. Less common but possible effects are dry mouth, dizziness, or throat irritation, and people with stomach ulcers should use it cautiously.

How many doses of ambroxol + levocetirizine combinations can be used per day?

For adults, ambroxol + levocetirizine tablets are usually taken once or twice daily, depending on the doctor’s advice and the severity of symptoms. In some cases, dosing may start at one tablet three times daily for 2–3 days, then reduced to twice daily.

1. Drugs.com. Ambroxol: Uses, Side Effects & Warnings [Internet]. Drugs.com; [cited 2026 Feb 26]. Available from. 
2. DrugBank Online. Ambroxol: Uses, Interactions, Mechanism of Action. DrugBank ID: DB06742 [Internet]. DrugBank; [cited 2026 Feb 26]. Available from. 
3. Kantar A, Klimek L, Cazan D, Sperl A, Sent U, Mesquita M. An overview of efficacy and safety of ambroxol for the treatment of acute and chronic respiratory diseases with a special regard to children. Multidiscip Respir Med.Available from. 
4. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 108013.Available from. 
5. Drugs.com. Levocetirizine: Uses, Dosage, Side Effects & Warnings [Internet]. Drugs.com; [cited 2026 Feb 26]. Available from. 
6. Mayo Clinic. Levocetirizine (oral route): Side effects & dosage [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; c2026 [cited 2026 Feb 26]. Available from.