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| Uses | 1. To treat seasonal allergies or allergic rhinitis (running nose, sneezing and itching) 2. To treat swelling in nose (nasal polyps) |
| Common Side Effects | 1. Burning or stinging feeling right after applying 2. Itching or dryness at the site 3. Redness or irritation of the skin 4. Tingling or pain where applied |
| Additional Information | 1. Inform your doctor if you have recent nasal surgery, injury, or infections 2. Do not share the spray with others. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Spray the contents into each nostril by placing the nozzle inside the nose. |
Mometasone 0.05% is a nasal spray belonging to the class of steroids and used for various types of immune-related allergic rhinitis/seasonal allergies and nasal polyps
Mometasone works by binding to glucocorticoid receptors in skin cells and changing the gene function to decrease the production of inflammatory proteins. This results in reduced swelling, redness, and itching in the affected skin
It is considered safe to use during pregnancy.
It is safe to use while breastfeeding.
Avoid applying it to open wounds, ulcers, or severely damaged skin because it can increase systemic absorption and can cause toxicity
If you have previously had an allergy to this medicine, inform your doctor.
Mometasone does not interact with food products, as it can be applied on the skin only. So, it is safe to use without any fear of food interactions.
Avoid taking mometasone 0.05 % with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate

Take mometasone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
Apply mometasone spray as per doctor’s instructions; do not consume orally. If ingested orally by mistake, overdose symptoms may occur and include nausea, irritation, and vomiting; excessive skin application causes marks on skin and burning sensations.
Mometasone nasal spray (0.05%) is a corticosteroid used for allergic rhinitis and nasal polyps. It works by reducing inflammation in the nasal passages through suppression of immune chemicals. Relief usually begins within a few days, but maximum benefit may take up to two weeks with regular use. Common side effects include nosebleeds, nasal irritation, sore throat, and headache. Since it is applied locally in the nose, there are no food interactions, but patients with recent nasal surgery, untreated nasal infections, or allergies to corticosteroids should avoid it. Children should use it only under strict medical guidance, as long-term use may affect growth. Overdose is uncommon, but using multiple sprays far beyond the prescribed dose or applying it for extended periods without supervision can increase the risk of systemic steroid effects
Mometasone nasal spray reduces inflammation in the nose by binding to glucocorticoid receptors, which suppresses the release of inflammatory mediators and decreases swelling, mucus production, and irritation in the nasal passages. This leads to relief from congestion, sneezing, and runny nose.
The most common side effects of mometasone nasal spray are mild and include nosebleeds, nasal irritation, sore throat, headache, and an unpleasant taste or smell. Rare but serious effects can include fungal infections (thrush), vision changes, or systemic steroid effects if used in very high doses or for prolonged periods.
Mometasone nasal spray has relatively few drug interactions, but caution is advised when used with other corticosteroids or medicines that affect immune function.
Yes, mometasone is a super-potent topical corticosteroid (steroid medicine) used on the skin to reduce inflammation, redness, and itching in conditions like psoriasis and eczema.

Written By-
Siva Krishna Adithya BhumireddyMedical content writer
Bachelors in Pharmacy | 1+ Year experience

Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 13 Mar 2026
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