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Hydroquinone 2 % + Mometasone 0.1 % + Tretinoin 0.025 % | Cream

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Hydroquinone 2 % + Mometasone 0.1 % + Tretinoin 0.025 % | Cream

Drug Code: 459

| creamcream| Pack of 15 gm
MRP ₹135.94

₹33

75% off

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₹ 2.2/gm

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Batch Details

Composition

Hydroquinone 2 % + Mometasone 0.1 % + Tretinoin 0.025 %

Batch

44|E2617

Expiry

April 2028

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Same active ingredients

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Batch Details

Composition

Hydroquinone 2 % + Mometasone 0.1 % + Tretinoin 0.025 %

Batch

44|E2617

Expiry

April 2028

About Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025%

Hydroquinone + Mometasone + Tretinoin cream is a combination skin medicine mainly used to treat melasma, dark spots, pigmentation, and uneven skin tone on the face. Hydroquinone helps lighten dark patches by reducing the formation of skin pigment, tretinoin helps remove old, pigmented skin cells and promotes new skin cell growth, and mometasone helps reduce redness, swelling, and irritation. Together, they help improve dark patches and make the skin tone look more even. Common side effects may include burning, redness, itching, dryness, peeling, and irritation. This cream should be used only for a short period as advised by the doctor, along with sunscreen during the day. 

Medicine Highlights

Uses 1. To treat melasma (dark patches on the skin) 
2. To treat skin pigmentation 
3. To treat dark spots on the face 
4. To help lighten uneven skin tone
Common Side Effects  1. Burning sensation 
2. Redness 
3. Itching 
4. Skin irritation 
5. Dryness 
6. Peeling of skin 
7. Mild stinging
Additional Information 1. Take it exactly as prescribed by your doctor. 
2. Avoid smoking, as it can reduce the medicine’s effect. 
3. Inform your doctor if you have heart, liver, or kidney problems.
Storage 1. The medicine should be stored at room temperature.
2. Keep away from sunlight and moisture.
3. Keep away from the reach of children
How to Take This MedicineApply a thin layer of the cream on the affected skin only. 

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% Uses

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% cream is a combination skin medicine used to treat the following conditions:

  1. Melasma (dark patches on the face) 
  2. Hyperpigmentation 
  3. Dark spots 
  4. Uneven skin tone 

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% side effects

More Common  

  1. Burning sensation 
  2. Redness 
  3. Itching 
  4. Dryness 
  5. Peeling of skin 
  6. Skin irritation 
  7. Mild stinging  

Less Common 

  1. Skin thinning 
  2. Increased sensitivity to sunlight 
  3. Acne or pimples 
  4. Darkening after irritation (in some people) 
  5. Stretch mark-like skin changes (with long use)  

How Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% works

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% cream works in three ways to help reduce dark patches on the skin. Hydroquinone helps lighten the skin by reducing the production of melanin, a protein responsible for the dark spots. Tretinoin helps remove old, pigmented skin cells and supports new skin cell growth, which improves skin tone. Mometasone is a steroid that helps reduce redness, swelling, and irritation caused by other ingredients. Together, they help fade pigmentation and improve the appearance of the skin. 

Safety Measures and Warning

Allergy or Hypersensitivity

If you are allergic to this medicine ie consult your doctor before using it because it can cause serious allergic reactions like rash, swelling, severe itching, or irritation. 

Sensitive or damaged skin

If you have very sensitive skin, cuts, wounds, sunburn, or damaged skin, consult your doctor before using this medicine because it can cause severe burning, irritation, and worsening of skin damage. 

Eczema or skin rash

If you have eczema, severe skin allergy, or skin rash, consult your doctor before using this medicine because it can make irritation worse and may not be suitable.

Skin infection

If you have a fungal, bacterial, or viral skin infection, consult your doctor before using this medicine because the steroid part can hide the infection and make it worse.

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% Interaction with Food Product

There are no major food interactions with this cream because it is applied on the skin. However, avoid alcohol-based skin products, harsh scrubs, strong soaps, and other irritating skincare products while using it, as they can increase burning, dryness, and skin irritation. Also avoid direct sunlight and always use sunscreen during the day. 

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% Interaction with Other Medicines

Avoid taking Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Hydroquinone: benzene-1,4-diol 

Hydroquinone 2%

Mometasone: (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 

Mometasone 0.1%

Tretinoin: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid 

Tretinoin 0.025%

Intake routine/cycle

Daily dose

Take Hydroquinone 2% + Mometasone 0.1% + Tretinoin 0.025% exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

it is not recommended to take this combination more than the prescribed dose by doctor, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.

Storage

  1. Store the medicine at room temperature. 
  2. Keep away from sunlight and moisture. 
  3. Keep out of reach of children. 

Directions for use

  1. Wash and dry the affected skin before applying the cream. 
  2. Take a small amount and apply a thin layer only on the affected area. 
  3. Gently spread it evenly without rubbing too hard. 
  4. Use it once daily at night or exactly as advised by your doctor. 
  5. Avoid contact with the eyes, mouth, nose, and broken skin. 
  6. Wash your hands after applying, unless your hands are the treated area.  take Tiotropium, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

FAQ’s

What are the uses of Hydroquinone cream? 

Hydroquinone cream is used to treat melasma, dark spots, skin pigmentation, acne marks, and uneven skin tone. 

What are the side effects of Hydroquinone cream? 

Common side effects of Hydroquinone cream may include burning, redness, itching, dryness, mild irritation, and peeling of the skin. 

What are the uses of Mometasone cream? 

Mometasone cream is used to treat skin redness, itching, swelling, eczema, dermatitis, and allergic skin conditions. 

What are the side effects of Mometasone cream? 

Common side effects of Mometasone cream may include burning, itching, dryness, irritation, skin thinning, and acne-like eruptions with long-term use. 

What are the uses of Tretinoin cream? 

Tretinoin cream is used to treat acne, acne marks, dark spots, skin pigmentation, fine lines, and uneven skin tone. 

What are the side effects of Tretinoin cream? 

Common side effects of Tretinoin cream may include redness, dryness, peeling, burning, stinging, irritation, and increased sensitivity to sunlight. 

Reference

  1. PubChem. Hydroquinone [Internet]. @pubchem. PubChem; 2020. Available from 
  2. Schwartz C, Jan A, Zito PM. Hydroquinone [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from 
  3. Mometasone topical Uses, Side Effects & Warnings [Internet]. Drugs.com. Available from 
  4. Mometasone (Nasonex): Uses & Side Effects [Internet]. Cleveland Clinic. Available from 
  5. Tretinoin (Topical Route) Description and Brand Names – Mayo Clinic [Internet]. Available from 
  6. Tretinoin Topical: MedlinePlus Drug Information [Internet]. medlineplus.gov. Available from  
Pranathi Chintaluri avatar

Written By-

Pranathi Chintaluri

Medical content writer

Doctor of Pharmacy | 2+ Year experience

Mahak Phartyal avatar

Reviewed By-

Mahak Phartyal

Medical Content writer and reviewer

Bachelors in Pharmacy | 3+ Year experience

Last Updated: 09 Jul 2026

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