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Dicyclomine 10 mg + Mefenamic Acid 250 mg tablet is an antispasmodic + non-steroidal anti-inflammatory drug (NSAID) combination. Dicyclomine 10 mg + Mefenamic Acid 250 mg is used to treat conditions like abdominal cramps, menstrual pain, and intestinal spasms. Dicyclomine works by relaxing the muscles of the stomach and intestines, while mefenamic acid reduces pain and inflammation, providing effective relief from cramps and discomfort.
It is usually taken after food as prescribed by the doctor. Common side effects of Dicyclomine 10 mg + Mefenamic Acid 250 mg include nausea, dry mouth, dizziness, drowsiness, and stomach discomfort. This medicine should be used with caution in patients with stomach ulcers, kidney, liver, or heart problems, and should be avoided during pregnancy unless advised by a doctor. Avoid alcohol, as it may increase the risk of stomach irritation and drowsiness.
| Uses | 1. To treat abdominal pain (stomach cramps) 2. To relieve menstrual pain (period pain) |
| Common Side Effects | 1. Nausea 2. Dry mouth 3. Dizziness 4. Drowsiness 5. Stomach pain |
| Additional Information | 1. Take it exactly as prescribed by your doctor. 2. Avoid smoking, as it can reduce the medicine’s effect. 3. Inform your doctor if you have heart, liver, or kidney problems. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water. |
Dicyclomine 10 mg + Mefenamic Acid 250 mg is an Antispasmodic + Non-Steroidal Anti-Inflammatory Drug (NSAID) combination used to treat conditions like:
This medication consists of dicyclomine and mefenamic acid. Dicyclomine is an antispasmodic that relaxes the muscles in the stomach and intestines, reducing cramps. Mefenamic acid is a pain-relieving medicine (NSAID) that reduces inflammation and pain. Together, they provide effective relief from abdominal and menstrual cramps.
If you have any allergy to Dicyclomine 10 mg + Mefenamic Acid 250 mg, inform your doctor before taking this medicine because it may cause reactions like rash, itching, swelling, or breathing difficulty.
If you have stomach ulcers or bleeding problems, inform your doctor because Dicyclomine 10 mg + Mefenamic Acid 250 mg can worsen irritation, bleeding, or stomach pain.
If you have heart problems, inform your doctor because painkillers like mefenamic acid may increase the risk of complications.
If you have liver problems, inform your doctor because improper digestion and enzyme imbalance may worsen your condition or reduce the effectiveness of the medicine.
If you have severe kidney disease, inform your doctor because accumulation of certain components may increase side effects.
If you are pregnant, inform your doctor before using Dicyclomine 10 mg + Mefenamic Acid 250 mg because although generally safe, it should only be used when clearly needed to avoid any possible risk to the baby.
If you are breastfeeding, inform your doctor because it is not clearly known whether Dicyclomine 10 mg + Mefenamic Acid 250 mg passes into breast milk and it may affect the baby.
Avoid alcohol as it may increase the risk of stomach irritation, bleeding, and drowsiness. Avoid spicy and oily foods as they may worsen stomach discomfort and acidity while taking this medicine. Limit caffeine intake as it may increase stomach irritation.
Avoid taking Dicyclomine 10 mg + Mefenamic Acid 250 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Dicyclomine: 2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate

Mefenamic Acid: 2-(2,3-dimethylanilino)benzoic acid

Take Dicyclomine 10 mg + Mefenamic Acid 250 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
It is not recommended to take more than the prescribed dose by doctor, as it may cause severe overdose symptoms like nausea, vomiting, headache, tremors, restlessness, and rapid heartbeat.
This combination is used to relieve pain and abdominal cramps. Mefenamic acid reduces pain and inflammation, while dicyclomine relaxes the muscles of the stomach and intestines. It is commonly used to treat menstrual pain (period cramps) and abdominal colic or spasms.
Common side effects include nausea, vomiting, stomach pain, dryness of mouth, dizziness, and drowsiness. Some people may also experience constipation or blurred vision. These are usually mild but should be monitored.
This medicine should be avoided in people with allergy to NSAIDs, stomach ulcers, severe kidney or liver problems, glaucoma, or urinary retention. It is also not recommended during late pregnancy and should be used cautiously in elderly patients.


Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 28 Apr 2026
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