Diabetes

This drug contain Metformin (er) 1000 mg+ dapagliflozin 10 mg.

Metformin (ER) and dapagliflozin are two different medications used to treat type 2 diabetes. When combined, they can work synergistically to help manage blood sugar levels.,,Metformin (ER) 1000 mg: Metformin is a first-line oral medication for type 2 diabetes. It belongs to the biguanide class of drugs. Metformin works by several mechanisms:

a. Decreasing glucose production in the liver: Metformin inhibits the liver's production of glucose, which helps reduce the excessive release of glucose into the bloodstream.,,b. Increasing insulin sensitivity: Metformin improves the body's response to insulin, allowing cells to take up more glucose from the blood, thus lowering blood sugar levels.,,c. Slowing glucose absorption from the intestines: Metformin can reduce the absorption of glucose from the food we eat, further controlling blood sugar spikes.,,Dapagliflozin 10 mg: Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor. It works by blocking a specific protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. This action allows excess glucose to be excreted in the urine, reducing blood sugar levels.,,Combining Metformin (ER) 1000 mg and dapagliflozin 10 mg can have a complementary effect in managing type 2 diabetes:,,Metformin addresses insulin resistance and reduces the liver's glucose production, which primarily targets fasting blood sugar levels.,,Dapagliflozin primarily affects post-meal blood sugar levels by increasing urinary glucose excretion.

The combination of these two medications can lead to better blood sugar control throughout the day, both before and after meals. However, it's essential to consult with a healthcare professional before starting or changing any diabetes medication regimen. They can provide personalized advice based on your medical history and current health status.

Type 2 Diabetes Management: Metformin is a commonly prescribed oral medication for type 2 diabetes. It belongs to the class of drugs called biguanides and helps lower blood glucose levels by reducing the amount of sugar produced by the liver and increasing the sensitivity of muscle cells to insulin. Dapagliflozin, on the other hand, is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, which works by reducing the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine. By combining these two medications, their complementary actions help control blood sugar levels more effectively.,,Dual Action: The combination of metformin and dapagliflozin provides a dual mechanism of action, making it particularly useful for people with type 2 diabetes who have not achieved sufficient blood sugar control with metformin alone or those who cannot tolerate metformin at higher doses.,,Weight Management: Dapagliflozin is associated with weight loss, which can be beneficial for individuals with type 2 diabetes who are overweight or obese. It achieves this by promoting the excretion of excess glucose in the urine, which also leads to the loss of calories.,,Cardiovascular Benefits: Some studies have suggested that dapagliflozin may have cardiovascular benefits, reducing the risk of heart failure and cardiovascular events in patients with type 2 diabetes.,,Convenience: The combination of metformin and dapagliflozin in a single tablet can be more convenient for patients who are prescribed both medications. It reduces the number of pills they need to take and simplifies their medication regimen.,,It's important to note that all medications can have side effects and may not be suitable for everyone. This combination should be prescribed and monitored by a healthcare professional who can assess the individual's specific medical history and needs.

As with any diabetes treatment, lifestyle modifications such as a healthy diet, regular exercise, and weight management are essential components of a comprehensive diabetes management plan. Always follow your healthcare provider's advice and attend regular check-ups to monitor your blood sugar levels and overall health.

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

Gastrointestinal Issues: Both Metformin and dapagliflozin can cause gastrointestinal side effects. These may include nausea, vomiting, diarrhea, abdominal discomfort, and bloating. These effects are usually mild and tend to improve with time.,,Hypoglycemia (low blood sugar): While Metformin and dapagliflozin are less likely to cause hypoglycemia when taken alone, the risk of low blood sugar may increase when these drugs are used together, especially if taken with other diabetes medications.,,Genital and Urinary Tract Infections: Dapagliflozin, being a sodium-glucose co-transporter-2 (SGLT2) inhibitor, can increase the risk of genital yeast infections in women and urinary tract infections in both men and women.,,Increased Urination: Dapagliflozin works by increasing the excretion of glucose through urine, which may result in increased frequency of urination.,,Dehydration: Dapagliflozin can lead to increased urinary water loss, which may cause dehydration, especially in older adults or those taking diuretics (water pills).,,Lactic Acidosis (rare but serious): Metformin has a rare but potentially serious side effect called lactic acidosis. This condition involves a buildup of lactic acid in the blood and can be life-threatening. It is more likely to occur in people with kidney or liver problems.,,Weight Changes: Some people may experience weight loss with dapagliflozin, while others might gain weight due to improved glycemic control with Metformin.,,Hypotension (low blood pressure): Dapagliflozin can cause a mild drop in blood pressure, which may lead to symptoms like dizziness or fainting, especially in those with low blood pressure to start with.,,Hypersensitivity Reactions: In rare cases, both medications can cause allergic reactions, such as rash, itching, and swelling of the face, tongue, or throat, which requires immediate medical attention.

It's essential to discuss any concerns or potential side effects with your healthcare provider before starting or during the course of the treatment. They can provide personalized advice based on your medical history and other medications you might be taking.

Warning: Metformin (er) 1000 mg and dapagliflozin 10 mg are medications commonly used to treat type 2 diabetes. Metformin is an oral antidiabetic drug that helps lower blood sugar levels by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues. Dapagliflozin is an SGLT-2 inhibitor, which works by reducing glucose reabsorption in the kidneys, leading to increased glucose excretion in the urine and lowering blood sugar levels.,,When taken together, metformin and dapagliflozin can complement each other's effects and provide better glycemic control for individuals with type 2 diabetes. However, like all medications, they may also have side effects and potential interactions. It's essential to follow your doctor's instructions, report any adverse reactions, and attend regular check-ups to monitor your response to the medications.,,Some possible side effects of metformin may include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Dapagliflozin, on the other hand, may lead to increased urination and an increased risk of urinary tract infections. Both medications may also be associated with certain rare but serious side effects like lactic acidosis (with metformin) and ketoacidosis (with dapagliflozin).,,Always inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid any potential interactions or adverse effects.,,If you experience any unexpected or severe side effects while taking these medications, seek immediate medical attention or contact your healthcare provider for guidance. They will be able to provide you with the most relevant and personalized advice.

Drug drug interaction: Metformin and dapagliflozin are both medications used to treat type 2 diabetes. When taking multiple medications, there is a possibility of drug interactions, which may affect how the medications work or increase the risk of side effects.,,One potential drug that can interact with metformin and dapagliflozin is insulin or other diabetes medications. Using these medications together may increase the risk of hypoglycemia (low blood sugar). Your doctor will carefully adjust the dosages and monitor your blood sugar levels to prevent this.,,Other drugs that can interact with metformin and dapagliflozin include certain medications used to treat high blood pressure, diuretics (water pills), and medications that affect the kidneys. Again, it's crucial to speak with a healthcare professional to ensure safe and effective medication use.,,Additionally, certain medical conditions may increase the risk of drug interactions, so it's essential to provide your healthcare provider with a complete list of all medications, supplements, and medical conditions you have to avoid potential complications.,,Always follow your healthcare provider's advice and inform them of any changes in your health or medications you may be considering. They can best guide you on how to manage potential drug interactions while taking metformin and dapagliflozin or any other medications.

Drug food interaction: Metformin is usually taken with meals to help reduce stomach upset. Taking it with food can slow the absorption of the medication, which may help minimize certain side effects. However, your doctor may have specific instructions for you based on your individual health condition.,,As for Dapagliflozin, it is usually taken once daily in the morning, with or without food. Again, your doctor will provide guidance on the best way to take this medication for your particular situation.,,It's essential to communicate with your healthcare provider or pharmacist about any concerns you may have regarding food interactions or any other aspects of your medication regimen. They will be able to provide personalized advice and address any potential issues related to food or drug interactions.

Drug disease interaction: Metformin (ER) 1000 mg and dapagliflozin 10 mg are commonly prescribed medications used in the treatment of type 2 diabetes mellitus. Metformin is a biguanide medication that helps lower blood sugar levels by reducing the amount of glucose produced by the liver and increasing insulin sensitivity in the body. Dapagliflozin, on the other hand, is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by reducing the reabsorption of glucose by the kidneys, leading to increased glucose excretion in the urine and lowering blood sugar levels.,,When used together, metformin and dapagliflozin can have a complementary effect on reducing blood sugar levels and improving glycemic control in people with type 2 diabetes. However, as with any medication, there can be potential interactions and side effects.,,One significant interaction of dapagliflozin with metformin is the risk of developing lactic acidosis. Both medications can independently increase the risk of lactic acidosis, but the risk may be higher when used together, especially in individuals with kidney impairment or other conditions that can predispose them to lactic acidosis. Lactic acidosis is a rare but serious condition characterized by the buildup of lactic acid in the bloodstream and can be life-threatening.

It is crucial to use these medications under the guidance and prescription of a healthcare professional who will consider the individual's medical history, kidney function, and other factors to ensure the safe and effective use of these drugs. Always follow the prescribed dosage and inform your healthcare provider about any other medications, supplements, or health conditions you may have to avoid potential interactions and adverse effects.

Hypersensitivity or Allergy: Patients who have a known hypersensitivity or allergy to either Metformin or dapagliflozin should not take this combination medication.,,Severe Renal Impairment or Kidney Dysfunction: Metformin is primarily excreted through the kidneys, and dapagliflozin's action is also partly dependent on renal function. Therefore, if a patient has severe kidney impairment or kidney dysfunction (eGFR <30 mL/min/1.73 m²), this combination should be avoided.,,Metabolic Acidosis: Metformin can rarely cause a serious condition called lactic acidosis, which is characterized by an excessive build-up of lactic acid in the body. Patients with metabolic acidosis, including diabetic ketoacidosis, should not take this combination medication.,,Type 1 Diabetes: This combination of Metformin ER and dapagliflozin is not indicated for the treatment of type 1 diabetes. It is specifically approved for use in type 2 diabetes.,,Acute or Chronic Kidney Disease: Dapagliflozin, as a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, may increase the risk of acute kidney injury. Therefore, caution is advised in patients with acute or chronic kidney disease.,,Severe Liver Impairment: Metformin is primarily eliminated through the liver, and in cases of severe liver impairment, the use of Metformin should be avoided or used with extreme caution.,,Alcohol Abuse: Excessive alcohol intake can increase the risk of lactic acidosis with Metformin use. Patients with a history of alcohol abuse should use this combination with caution or avoid it altogether.

It is essential for patients to discuss their medical history, current medications, and any pre-existing conditions with their healthcare provider before starting any new medication, including this combination of Metformin ER and dapagliflozin. This information helps ensure the safety and effectiveness of the treatment and avoids potential contraindications or drug interactions. Always follow your healthcare provider's advice and instructions regarding medication use.

Follow the prescribed dosage: Take the medications exactly as prescribed by your doctor. Do not take more or less than the prescribed dose.,,Take them with or after meals: Generally, it's recommended to take Metformin ER with meals to reduce the risk of stomach upset. Check with your doctor for specific instructions on when to take these medications.,,Stay hydrated: Drink plenty of water to help prevent dehydration, especially while taking Dapagliflozin, as it works by increasing urinary glucose excretion.,,Monitor blood sugar levels: Keep track of your blood sugar levels regularly and report any significant changes to your healthcare provider.,,Be aware of hypoglycemia: Both Metformin and Dapagliflozin can lower blood sugar levels. Be vigilant for signs of hypoglycemia (low blood sugar) such as shakiness, dizziness, sweating, confusion, and rapid heartbeat.,,Inform healthcare providers: Make sure all your healthcare providers are aware of all the medications you are taking, including prescription drugs, over-the-counter medications, and supplements.,,Watch for side effects: Be aware of potential side effects of these medications, such as nausea, diarrhea, urinary tract infections, or genital yeast infections (more common with Dapagliflozin).,,Avoid alcohol: Alcohol can affect blood sugar levels and may interact with these medications. Consult your doctor about alcohol consumption while taking them.,,Be cautious with certain medical conditions: Inform your doctor if you have any medical conditions like kidney or liver issues, heart problems, or a history of bladder infections, as these may affect the use of these medications.,,Regular check-ups: Attend regular follow-up appointments with your healthcare provider to monitor your response to the medications and make any necessary adjustments to your treatment plan.,,Remember, this is general advice and not a substitute for professional medical guidance. Always consult your doctor or healthcare provider before starting or making changes to any medication.

Store this medicine at room temperature, away from sunlight and moisture.

Type 2 Diabetes Management: Metformin is a commonly prescribed oral medication for type 2 diabetes. It belongs to the class of drugs called biguanides and helps lower blood glucose levels by reducing the amount of sugar produced by the liver and increasing the sensitivity of muscle cells to insulin. Dapagliflozin, on the other hand, is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, which works by reducing the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine. By combining these two medications, their complementary actions help control blood sugar levels more effectively.,,Dual Action: The combination of metformin and dapagliflozin provides a dual mechanism of action, making it particularly useful for people with type 2 diabetes who have not achieved sufficient blood sugar control with metformin alone or those who cannot tolerate metformin at higher doses.,,Weight Management: Dapagliflozin is associated with weight loss, which can be beneficial for individuals with type 2 diabetes who are overweight or obese. It achieves this by promoting the excretion of excess glucose in the urine, which also leads to the loss of calories.,,Cardiovascular Benefits: Some studies have suggested that dapagliflozin may have cardiovascular benefits, reducing the risk of heart failure and cardiovascular events in patients with type 2 diabetes.,,Convenience: The combination of metformin and dapagliflozin in a single tablet can be more convenient for patients who are prescribed both medications. It reduces the number of pills they need to take and simplifies their medication regimen.,,It's important to note that all medications can have side effects and may not be suitable for everyone. This combination should be prescribed and monitored by a healthcare professional who can assess the individual's specific medical history and needs.

As with any diabetes treatment, lifestyle modifications such as a healthy diet, regular exercise, and weight management are essential components of a comprehensive diabetes management plan. Always follow your healthcare provider's advice and attend regular check-ups to monitor your blood sugar levels and overall health.