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Medicine Highlights
| Uses | 1.To treat acute or chronic back pain 2. To treat muscle cramps or stiffness 3. To treat stiff spine (ankylosing spondylitis) 4. To treat swollen, painful joints in conditions like rheumatoid arthritis 5. To treat spine bone damage (vertebral damage) 6. To treat constant neck stiffness (torticollis) |
| Common Side Effects | 1. Drowsiness or sedation 2. Abdominal pain or discomfort 3. Gas or flatulence 4. Nausea 5. Diarrhea |
| Additional Information | 1. It should not be given to children below 2 years. 2. This medicine is available only with your doctor’s prescription. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | Swallow this medicine with water |
Thiocolchicoside Summary
Thiocolchicoside is a muscle relaxant used to relieve muscle spasms, stiffness, and pain caused by conditions like sciatica, back pain, and muscle injuries. It works by mimicking the action of Gamma-Aminobutyric Acid (GABA), a natural chemical that calms nerve activity and promotes muscle relaxation. Common side effects include drowsiness, dizziness, stomach discomfort, or diarrhea. High doses or long-term use may lead to side effects like seizures or fertility issues. It should be taken after food to reduce stomach upset and used with caution in people with epilepsy, liver or kidney problems, and should be avoided during pregnancy and breastfeeding.
Thiocolchicoside Uses
Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects, it is useful to treat the following indications:
- Acute or chronic back pain
- Muscle cramps or stiffness
- Stiff spine (ankylosing spondylitis)
- Swollen, painful joints in conditions like rheumatoid arthritis
- Spine bone damage (vertebral damage)
- Constant neck stiffness (torticollis)
Directions for use
- Take thiocolchicoside exactly as prescribed by your doctor, at the same time each day.
- Do not stop taking thiocolchicoside without your doctor’s approval, even if you feel better.
- If you forget to take thiocolchicoside, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.
Thiocolchicoside side effects
More Common
- Drowsiness or sedation
- Abdominal pain or discomfort
- Gas or flatulence
- Nausea
- Diarrhea
Less Common
- Nausea
- Dizziness
- Headache
- Drowsiness
- Constipation
- Palpitations
- Facial swelling
How Thiocolchicoside works
Thiocolchicoside is a medicine that helps relax tight or stiff muscles. It works on the nerves by attaching to special spots called Gamma-Aminobutyric Acid GABA receptors and slowing down certain signals that make muscles contract. This helps reduce pain and stiffness caused by muscle cramps, back pain, or sciatica; while letting you keep your normal muscle strength.
Safety Measures and Warning
📌 Pregnancy and Lactation
Avoid use during pregnancy and breastfeeding, as it may harm the fetus or infant.
📌 Seizure Risk
Use with caution if you have a history of epilepsy or seizure disorders, as it may lower the seizure threshold.
📌 Liver and Kidney Disease
Use with caution and only under medical advice if you have history of liver or kidney impairment.
📌 Drowsiness and Dizziness
This medication will cause sleepiness or dizziness, avoid driving or operating heavy machinery.
Thiocolchicoside Interaction with Food Products
Avoid consuming caffeinated foods which can lead to unwanted side effects like allergies and skin rashes. Alcohol and smoking can increase the potential of side effects occurring and worsen the patient’s conditions.
Thiocolchicoside Interaction with Other Medicines
Avoid taking thiocolchicoside with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Thiocolchicoside Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
N-[(7S)-1,2-dimethoxy-10-methylsulfanyl-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Intake routine/cycle
📌 Daily Dose
Take thiocolchicoside exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
📌 Missed Dose
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
📌 Overdose
Don’t take more than 16 mg of thiocolchicoside per day, The symptoms of overdosing may include abnormal sleepiness, inability to identify the right direction temporarily or suffering from shortness of breath. If you know someone who takes this medicine and has these symptoms, then rush them to the hospital immediately.
Storage
- Store the medicine at room temperature
- Keep away from sunlight and moisture
- Keep out of reach of children
FAQ’s
1. What is thiocolchicoside duration of action?
➡️ The duration of thiocolchicoside is about 8 to 12 hours. Its onset of action is 1 to 2 hours if it is taken orally and 30 minutes to 1 hour if it is taken in injectable form also its half-life is 1.5 hours.
2. What are thiocolchicoside tablets used?
➡️ Thiocolchicoside is a muscle relaxant that helps relieve back pain, muscle cramps, stiff spine (AS), joint swelling (arthritis), spine damage, and constant neck stiffness.
3. How to take thiocolchicoside 4 mg tablet?
➡️ Take it with or after food or a glass of milk. Thiocolchicoside may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking thiocolchicoside as it may cause excessive drowsiness.
4. How much does thiocolchicoside 4 mg tablet costs?
➡️ Thiocolchicoside 4 mg tablet costs around ₹7–₹13 per tablet in India, depending on the brand at SayaCare we provide test report with each medicine. Also, at SayaCare we provide you medicines with up to 80% less cost than on the market.
Reference
- PubChem. Thiocolchicoside [Internet]. Nih.gov. PubChem; 2025 [cited 2025 Jul 15]. Available from
- European Medicines Agency recommends restricting use of thiocolchicoside by mouth or injection | European Medicines Agency (EMA) [Internet]. European Medicines Agency (EMA). 2013 [cited 2025 Jul 15]. Available from
- Kamath A. Thiocolchicoside: A review. DHR International Journal of Medical Sciences (DHR-IJMS [Internet]. [cited 2025 Jul 15];4(2):2013. Available from
- Thiocolchicoside: Uses, Interactions, Mechanism of Action | DrugBank Online [Internet]. Drugbank.com. DrugBank; 2020. Available from