category
Heart
composition
This drug contain Telmisartan 40mg+ cilnidipine 10mg +chlorthalidone 12.5 mg.
workings
Telmisartan, Cilnidipine, and Chlorthalidone are three different medications often used in combination to treat hypertension (high blood pressure). Let's look at each medication's mechanism of action and how they work together:
Telmisartan:Telmisartan belongs to a class of medications known as angiotensin II receptor blockers (ARBs). It works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. By blocking angiotensin II, Telmisartan helps to relax and widen blood vessels, reducing blood pressure and improving blood flow.
Cilnidipine: Cilnidipine is a calcium channel blocker (CCB) that mainly blocks both L-type and N-type calcium channels in the blood vessels. By doing so, it reduces the entry of calcium into the smooth muscle cells of blood vessels, leading to relaxation and dilation of the blood vessels. This action helps to lower blood pressure.
Chlorthalidone:Chlorthalidone is a thiazide-like diuretic, commonly referred to as a water pill. It works in the kidneys by increasing the excretion of sodium and water from the body, which decreases the volume of fluid in the blood vessels. As a result, there is less fluid to pump through the blood vessels, and the heart's workload is reduced, leading to lower blood pressure.
When these three medications are combined, they work synergistically to lower blood pressure through different mechanisms:,,Telmisartan blocks the effect of angiotensin II, reducing vasoconstriction and promoting vasodilation.,,Cilnidipine relaxes and widens the blood vessels by blocking calcium channels.,,Chlorthalidone helps to reduce the volume of fluid in the blood vessels, further decreasing blood pressure.,,The combination of these three drugs allows for a more effective reduction in blood pressure compared to using each medication alone. However, it's essential to use this combination under the guidance and supervision of a healthcare professional, as it may not be suitable for everyone, and regular monitoring is necessary to ensure safety and efficacy. Additionally, the dosages may vary depending on the individual's condition and response to treatment.
usage
Telmisartan (40mg):Telmisartan is an angiotensin II receptor blocker (ARB). It works by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow. By blocking angiotensin II, telmisartan relaxes and widens the blood vessels, reducing blood pressure.
Cilnidipine (10mg):Cilnidipine is a calcium channel blocker (CCB). It works by blocking the entry of calcium into the smooth muscle cells of blood vessels and the heart. As a result, the blood vessels relax, and the heart's workload decreases, leading to lower blood pressure.
Chlorthalidone (12.5mg):Chlorthalidone is a thiazide-like diuretic, commonly referred to as a water pill. It increases the excretion of water and sodium from the body, which helps to reduce the overall blood volume. As blood volume decreases, it lowers the pressure on the blood vessel walls, further aiding in reducing blood pressure.,,Combining these three medications provides a synergistic effect in treating hypertension. It is essential to follow your doctor's instructions and regularly monitor your blood pressure while taking this medication. This combination may not be suitable for everyone, and its use depends on an individual's specific health condition, so always consult with a healthcare professional before starting or making any changes to your medication regimen.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Dizziness or lightheadedness,,Fatigue or weakness,,Diarrhea,,Back pain,,High potassium levels (hyperkalemia),,Headache,,Swelling in the ankles and feet (peripheral edema),,Headache,,Flushing (reddening of the skin),,Dizziness or lightheadedness,,Fatigue or weakness,,Frequent urination,,Dizziness or lightheadedness,,Muscle cramps,,Weakness or fatigue,,Low potassium levels (hypokalemia).
warnings
Warning: Telmisartan 40mg + Cilnidipine 10mg + Chlorthalidone 12.5 mg is a combination medication used to treat hypertension (high blood pressure). It contains three different active ingredients:,,Telmisartan: This belongs to a class of drugs known as angiotensin II receptor blockers (ARBs), which help relax blood vessels and lower blood pressure.,,Cilnidipine: This is a calcium channel blocker that also helps dilate blood vessels, reducing blood pressure.,,Chlorthalidone: This is a thiazide diuretic, which promotes diuresis (increased urination) and helps to lower blood pressure by reducing the volume of fluid in the blood vessels.,,As with any medication, there can be potential side effects and interactions. Some common side effects may include dizziness, headache, fatigue, or stomach upset. Serious side effects are rare but can occur.,,It's essential to take this medication as prescribed by your doctor and to follow up with them regularly to monitor your blood pressure and overall health.,,If you experience any unusual or severe symptoms while taking this medication, contact your healthcare provider immediately.
interactions
Drug drug interaction: Some medications that might interact with Telmisartan, Cilnidipine, and Chlorthalidone include:
Other blood pressure medications: Combining these drugs with other antihypertensive medications can potentially cause an excessive drop in blood pressure.,,Potassium-sparing diuretics and potassium supplements: Taking these together with Chlorthalidone may lead to increased potassium levels in the body, which can be harmful.,,Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, when taken with Telmisartan, may reduce the blood pressure-lowering effects of Telmisartan.,,Lithium: Taking lithium with these medications may lead to increased lithium levels in the body, potentially causing lithium toxicity.,,Grapefruit juice: Grapefruit juice can interfere with the metabolism of some medications, potentially increasing their levels in the body, including Cilnidipine.,,Other drugs that affect the renin-angiotensin-aldosterone system: Taking multiple drugs that affect this system can increase the risk of side effects.,,It is crucial to provide your healthcare professional with a complete list of all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They will be able to assess the potential for drug interactions and make appropriate adjustments to your medication regimen if necessary. Never make changes to your medication without proper medical supervision.
Drug food interaction: Telmisartan 40mg, Cilnidipine 10mg, and Chlorthalidone 12.5mg are medications used to treat high blood pressure (hypertension). When taking these medications, it's essential to be cautious about certain foods and substances that may interact with them. Some potential interactions include:,,Grapefruit and grapefruit juice: Grapefruit can interfere with the metabolism of certain medications, including Cilnidipine. It may lead to higher blood levels of the drug, potentially increasing its side effects. Therefore, it's generally recommended to avoid grapefruit or grapefruit juice while taking these medications.,,High-potassium foods: Chlorthalidone is a thiazide diuretic, which can cause potassium levels to decrease in the body. Foods high in potassium, such as bananas, oranges, tomatoes, and leafy greens, may reduce the effectiveness of the diuretic. While it's essential to maintain a balanced diet, it's a good idea to discuss your diet's potassium content with your healthcare provider.,,Alcohol: Drinking alcohol can increase blood pressure and may also interact with these medications, potentially leading to dizziness or fainting. It's best to limit or avoid alcohol while on antihypertensive medications.,,Salt (sodium): High-sodium diets can counteract the effects of antihypertensive medications by promoting water retention and increasing blood pressure. Reducing sodium intake can enhance the effectiveness of these medications.,,NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): Certain pain relievers like ibuprofen and naproxen can reduce the effectiveness of antihypertensive drugs and may cause further blood pressure elevation. If you need to take pain medication, it's essential to discuss it with your healthcare provider to find a suitable alternative.,,Always consult your healthcare provider or pharmacist regarding any potential interactions with specific foods or medications. They can provide personalized advice based on your medical history and individual needs. Additionally, remember to take your medications as prescribed and attend regular follow-up appointments to monitor your blood pressure and adjust your treatment as necessar.
Drug disease interaction: The combination of Telmisartan 40mg, Cilnidipine 10mg, and Chlorthalidone 12.5mg is a medication used to treat hypertension (high blood pressure). Let's take a closer look at each component of the combination:,,Telmisartan: It belongs to a class of medications known as angiotensin II receptor blockers (ARBs), which help to relax blood vessels, thereby reducing blood pressure.,,Cilnidipine: It is a calcium channel blocker that also works to relax and widen blood vessels, leading to decreased blood pressure.,,Chlorthalidone: This is a thiazide diuretic that helps the body eliminate excess salt and water, which can further reduce blood volume and lower blood pressure.,,Combining these three drugs allows for a more comprehensive approach to managing hypertension, as they work through different mechanisms to achieve blood pressure reduction. Always remember to take this medication as prescribed by your doctor and follow up with them regularly to monitor your blood pressure and overall health.
contraindications
Telmisartan 40mg + Cilnidipine 10mg + Chlorthalidone 12.5 mg is a combination medication used to treat high blood pressure (hypertension). However, like any medication, it has its contraindications, which are situations or conditions where the drug should not be used due to potential risks or lack of effectiveness. Some contraindications for this combination medication may include:
Hypersensitivity or Allergy: If a person has a known allergy or hypersensitivity to any of the active ingredients (Telmisartan, Cilnidipine, or Chlorthalidone) or any other components of the medication, it should not be used.,,Severe Renal Impairment: The combination is not recommended for patients with severe kidney impairment or end-stage renal disease, as it may worsen the condition or lead to complications.,,Severe Hepatic Impairment: Individuals with severe liver problems should avoid this medication, as it may not be properly metabolized and could cause harm.,,Pregnancy: This combination is not recommended during pregnancy, especially during the second and third trimesters, as it can be harmful to the fetus. Pregnant women should consult their doctor for alternative treatment options.,,Breastfeeding: It is not advised to use this medication while breastfeeding, as it may pass into breast milk and harm the nursing infant.,,Patients with Anuric Conditions: Anuric conditions are when the kidneys stop producing urine, and in such cases, this medication should be avoided.,,History of Angioedema: Individuals with a history of angioedema (swelling of the face, lips, tongue, throat, or extremities) associated with previous use of ACE inhibitors or ARBs (angiotensin receptor blockers) may be at increased risk of developing a similar reaction with Telmisartan, which is an ARB.,,Hypotension: The combination may cause a drop in blood pressure, so it should be used with caution in patients with low blood pressure (hypotension).,,Aortic or Mitral Valve Stenosis: Patients with aortic or mitral valve stenosis (narrowing of heart valves) may be at risk of worsening the condition with this medication.
It is essential to consult a healthcare professional before starting or stopping any medication, including Telmisartan 40mg + Cilnidipine 10mg + Chlorthalidone 12.5 mg, to ensure it is safe and appropriate for individual circumstances. Additionally, a healthcare provider can consider potential drug interactions and assess any other medical conditions the patient may have.
other
Follow Dosage Instructions: Take the medication exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider.,,Take with Caution: Be cautious if you have any pre-existing medical conditions, allergies, or if you are taking other medications. Inform your doctor about all your medical history and ongoing treatments.,,Avoid Alcohol: Alcohol can interact with these medications and may increase the risk of side effects. It is generally best to avoid alcohol while on medication.,,Stay Hydrated: Chlorthalidone is a diuretic, which means it can increase urination. Drink enough water to stay hydrated.,,Monitor Blood Pressure: These medications are commonly used to treat hypertension (high blood pressure). Regularly monitor your blood pressure as advised by your doctor.,,Report Side Effects: If you experience any unusual or severe side effects while taking this medication, contact your doctor immediately.,,Maintain a Healthy Lifestyle: Medications are often more effective when combined with a healthy lifestyle. Adopt a balanced diet, engage in regular physical activity, and avoid smoking.,,Keep a Medication List: Maintain a list of all the medications you are taking, including the dosage and frequency. Share this list with your doctor or pharmacist during every visit.,,Store Properly: Keep the medication in a cool, dry place, away from direct sunlight, and out of reach of children and pets.,,Avoid Grapefruit and Grapefruit Juice: Grapefruit and its juice can interfere with the metabolism of certain medications, including Cilnidipine. Avoid consuming grapefruit while taking this medication.,,Remember, individual responses to medications can vary, and what works for one person may not be suitable for another. Always consult your healthcare provider before starting or making changes to any medication regimen. They can assess your health status and adjust the treatment plan accordingly to ensure your safety and well-being.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Telmisartan (40mg):Telmisartan is an angiotensin II receptor blocker (ARB). It works by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow. By blocking angiotensin II, telmisartan relaxes and widens the blood vessels, reducing blood pressure.
Cilnidipine (10mg):Cilnidipine is a calcium channel blocker (CCB). It works by blocking the entry of calcium into the smooth muscle cells of blood vessels and the heart. As a result, the blood vessels relax, and the heart's workload decreases, leading to lower blood pressure.
Chlorthalidone (12.5mg):Chlorthalidone is a thiazide-like diuretic, commonly referred to as a water pill. It increases the excretion of water and sodium from the body, which helps to reduce the overall blood volume. As blood volume decreases, it lowers the pressure on the blood vessel walls, further aiding in reducing blood pressure.,,Combining these three medications provides a synergistic effect in treating hypertension. It is essential to follow your doctor's instructions and regularly monitor your blood pressure while taking this medication. This combination may not be suitable for everyone, and its use depends on an individual's specific health condition, so always consult with a healthcare professional before starting or making any changes to your medication regimen.