Allergy

This is an immunosuppressive drug .ie Tacrolimus 0.25 mg.

Tacrolimus 0.25 mg | 10 tablets is a medication that is used to suppress the immune system. It is typically used in organ transplant patients to prevent rejection of the transplanted organ.,,The medication works by inhibiting the activity of certain immune cells, called T cells, which play a crucial role in the rejection process. By reducing the activity of these cells, tacrolimus helps to prevent the body from attacking and rejecting the transplanted organ.

Immunosuppression in organ transplantation: Tacrolimus 0.25 mg tablets are used to prevent rejection of transplanted organs such as kidney, liver, heart, and lung.,,Treatment of atopic dermatitis: Tacrolimus 0.25 mg tablets can be used to reduce inflammation and itching in patients with atopic dermatitis.,,Management of autoimmune diseases: Tacrolimus 0.25 mg tablets may be used to treat autoimmune disorders such as rheumatoid arthritis and psoriasis.,,Prevention of graft-versus-host disease: Tacrolimus 0.25 mg tablets can be used to prevent GVHD (Graft-versus-host disease) in patients who have undergone bone marrow transplantation.,,Management of inflammatory bowel disease: Tacrolimus 0.25 mg tablets may be used to treat inflammatory bowel disease such as Crohn's disease and ulcerative colitis.,,Treatment of other inflammatory conditions: Tacrolimus 0.25 mg tablets can be used to treat other inflammatory conditions such as sarcoidosis, nephrotic syndrome, and vasculitis.,,Dosage adjustment for kidney and liver impairment: Tacrolimus 0.25 mg tablets may be used to adjust the dosage of tacrolimus in patients with kidney or liver impairment.

Tacrolimus 0.25 mg is a medication used to suppress the immune system and prevent organ rejection in transplant patients. It comes in the form of 10 tablets, each containing 0.25 mg of the active ingredient tacrolimus. The tablets are usually taken once or twice daily, as directed by a healthcare provider. Tacrolimus works by inhibiting the activity of certain cells in the immune system, which can reduce the risk of organ rejection. However, it can also increase the risk of certain infections and other side effects, so it is important to closely monitor the patient while taking this medication.

Increase in blood sugar levels,,increased blood cholesterol levels,,difficulty in falling asleep,,increased blood potassium levels,,high blood pressure,,headache,, dizziness,,indigestion,,oedema and increased infections.

Warning : Consult your doctor if you have any kidney or liver or any heart diseases. Do not consume alcohol while taking tacrolimus . if you are allergic to Tacrolimus or to any macrolide antibiotics (such as erythromycin, azithromycin).

Drug drug interaction : Blood pressure medications such as ACE inhibitors, ARBs, and calcium channel blockers. These interactions can increase the risk of hypertension or decreased blood pressure.,,Immunosuppressants such as cyclosporine and sirolimus. These interactions can increase the risk of nephrotoxicity, hyperkalemia, and increased risk of infection.,,Antacids and proton pump inhibitors. These interactions can decrease the absorption of tacrolimus and reduce its effectiveness.,,Antibiotics such as clarithromycin and erythromycin. These interactions can increase the risk of nephrotoxicity and decreased efficacy of tacrolimus.,,Corticosteroids such as prednisone. These interactions can increase the risk of glucose intolerance, osteoporosis, and increased risk of infection.

Drug food interaction : Grapefruit and grapefruit juice: These contain compounds that can increase the absorption of tacrolimus, potentially leading to higher blood levels and an increased risk of side effects. It is recommended to avoid consuming grapefruit or grapefruit juice while taking tacrolimus.,,Calcium-rich foods: Tacrolimus can bind to calcium in the gut, reducing its absorption and effectiveness. To avoid this interaction, it is recommended to take tacrolimus at least two hours before or after consuming calcium-rich foods such as dairy products, almonds, and spinach.,,Antacids: Tacrolimus can interact with antacids containing aluminum or magnesium, reducing its absorption and effectiveness. To avoid this interaction, it is recommended to take tacrolimus at least two hours before or after taking antacids.,,Other medications: Tacrolimus can interact with a number of other medications, including antibiotics, antifungals, blood pressure medications, and certain antidepressants. It is important to inform your healthcare provider of all medications and supplements you are taking before starting tacrolimus 0.25 mg.

Drug disease interaction : Increased risk of infections: Tacrolimus suppresses the immune system, making patients more susceptible to infections such as pneumonia, sepsis, and fungal infections. Patients should be closely monitored for signs of infection and treated promptly if any occur.,,Increased risk of malignancy: Tacrolimus has been associated with an increased risk of skin cancer and lymphoma. Patients should be advised to use sunscreen and avoid prolonged sun exposure.,,Increased risk of kidney dysfunction: Tacrolimus can cause nephrotoxicity, which can lead to kidney dysfunction. Patients with pre-existing kidney problems should be closely monitored for signs of kidney dysfunction and have their dosage adjusted accordingly.,,Interaction with other drugs: Tacrolimus can interact with other drugs, such as cyclosporine, warfarin, and digoxin. Patients should inform their healthcare provider of all medications they are taking.

Take tacrolimus exactly as prescribed by your healthcare provider. Do not change the dose or stop taking it without talking to your healthcare provider first.,,Tacrolimus can cause serious side effects, so it is important to have regular blood tests to check your kidney and liver function, as well as your blood cell counts.,,Tell your healthcare provider if you have any other medical conditions, such as diabetes, high blood pressure, or a history of infections.,,Avoid exposure to sunlight or UV light while taking tacrolimus, as it can increase your risk of skin cancer. Wear protective clothing and use sunscreen with at least SPF 30.,,Avoid taking other medications that may interact with tacrolimus, such as antibiotics, antifungal drugs, or blood thinners.,,If you experience any side effects such as fever, chills, or difficulty breathing, contact your healthcare provider immediately.,,Be sure to keep all of your appointments with your healthcare provider and follow up as recommended.

Tacrolimus 0.25 mg is not generally considered safe for use during pregnancy or breastfeeding. Tacrolimus is classified as a pregnancy category C medication, which means that it may be harmful to a developing fetus. It is also not known if tacrolimus is excreted in breastmilk, so it is not recommended for use during breastfeeding. If you are pregnant or breastfeeding, it is important to talk to your doctor about the risks and benefits of taking tacrolimus before making a decision about its use..

Store this medicine at room temperature, away from sunlight and moisture.

Swallow the tablets /capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.