This drug contain Sitagliptin 50 mg + metformin 500 mg

Sitagliptin and metformin are two medications commonly used together to manage type 2 diabetes. Sitagliptin is a medication that belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, while metformin is a biguanide medication.

Sitagliptin works by inhibiting the DPP-4 enzyme, which breaks down incretin hormones in the body. Incretin hormones help to increase insulin secretion from the pancreas and decrease the production of glucose by the liver. By inhibiting the DPP-4 enzyme, sitagliptin increases the levels of incretin hormones in the body, which helps to lower blood sugar levels.

Metformin works in several ways to lower blood sugar levels. It reduces the amount of glucose produced by the liver and increases the sensitivity of muscle and fat cells to insulin. This helps to improve the uptake of glucose by these cells and lower blood sugar levels.

When taken together, sitagliptin and metformin work synergistically to lower blood sugar levels in people with type 2 diabetes. Sitagliptin helps to increase insulin secretion and decrease glucose production, while metformin improves insulin sensitivity and reduces glucose production by the liver. The combination of these two medications can provide effective glycemic control in people with type 2 diabetes.

Sitagliptin 50 mg + metformin 500 mg is a combination medication that is used to treat type 2 diabetes.

The two active ingredients work in different ways to help control blood sugar levels:

Sitagliptin: This medication is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the amount of insulin released by the pancreas and reducing the amount of glucose produced by the liver. This helps to lower blood sugar levels after meals.,,Metformin: This medication is a biguanide that works by reducing the amount of glucose produced by the liver and increasing the body's sensitivity to insulin. This helps to lower fasting blood sugar levels.

The combination of sitagliptin and metformin is often used when metformin alone is not enough to control blood sugar levels or when a patient cannot tolerate a higher dose of metformin.

In summary, Sitagliptin 50 mg + metformin 500 mg is used to:

Lower blood sugar levels in people with type 2 diabetes,,Increase the body's sensitivity to insulin,,Reduce the amount of glucose produced by the liver,,Improve the overall management of type 2 diabetes.

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

Nausea,,Vomiting,,Diarrhea,,Abdominal discomfort or pain,,Loss of appetite,,Headache,,Dizziness,,Hypoglycemia (low blood sugar),,Upper respiratory tract infection.

Warning: Sitagliptin 50 mg + metformin 500 mg is a combination medication used to treat type 2 diabetes. While this medication can be effective in controlling blood sugar levels, there are some potential risks and side effects that you should be aware of. Here are a few warnings to keep in mind:

Hypoglycemia: This medication can cause your blood sugar levels to drop too low, especially if you are taking other diabetes medications in addition to Sitagliptin/metformin. Be sure to monitor your blood sugar levels regularly and talk to your doctor if you experience symptoms of hypoglycemia, such as shakiness, sweating, dizziness, or confusion.,,Pancreatitis: Rare cases of pancreatitis (inflammation of the pancreas) have been reported in people taking Sitagliptin/metformin. Seek medical attention right away if you experience severe abdominal pain that does not go away, as this could be a sign of pancreatitis.,,Lactic acidosis: This is a rare but serious condition that can occur when taking metformin. It occurs when there is a buildup of lactic acid in the blood. Symptoms may include muscle pain or weakness, difficulty breathing, stomach pain, nausea or vomiting, dizziness or lightheadedness, or an irregular heartbeat. Seek medical attention right away if you experience any of these symptoms.,,Allergic reactions: Some people may experience an allergic reaction to Sitagliptin/metformin. Seek medical attention right away if you experience symptoms such as hives, swelling of the face, lips, tongue, or throat, or difficulty breathing.,,Kidney problems: Both Sitagliptin and metformin can affect kidney function, and people with existing kidney problems may be at increased risk of complications. Talk to your doctor if you have any concerns about your kidney function.

As with any medication, it is important to talk to your doctor about the potential risks and benefits of Sitagliptin/metformin, and to report any side effects or concerns promptly.

Drug drug interaction: There are many drugs that can potentially interact with Sitagliptin 50 mg + metformin 500 mg, so it is important to consult with a healthcare professional before starting any new medications.

Some of the drugs that may interact with Sitagliptin 50 mg + metformin 500 mg include:

Insulin or other oral diabetes medications,,ACE inhibitors or ARBs (used to treat high blood pressure),,Corticosteroids (used to treat inflammation),,Diuretics (used to reduce fluid retention),,Cimetidine (used to treat stomach ulcers and acid reflux),,Rifampin (an antibiotic used to treat tuberculosis),,Beta-blockers (used to treat high blood pressure and heart conditions),,Digoxin (used to treat heart failure),,Furosemide (a diuretic used to treat fluid retention),,NSAIDs (nonsteroidal anti-inflammatory drugs).

Again, it is important to consult with a healthcare professional before starting any new medications to ensure there are no potential interactions.

Drug food interaction: Sitagliptin 50 mg + metformin 500 mg is a medication used to treat type 2 diabetes. There are several foods that can interact with this medication and affect its efficacy.,,One important thing to keep in mind when taking Sitagliptin and metformin is to avoid consuming excessive amounts of alcohol, as this can increase the risk of lactic acidosis, a potentially life-threatening condition.,,In terms of specific foods, it's generally recommended to take Sitagliptin and metformin with meals to help reduce the risk of gastrointestinal side effects. However, some foods may affect the absorption of the medication or cause changes in blood glucose levels.,,For example, consuming large amounts of high-glycemic-index carbohydrates (such as sugary drinks or processed snacks) can cause a rapid rise in blood glucose levels, which can counteract the effects of the medication. It's generally recommended to limit these types of foods and instead focus on consuming complex carbohydrates (such as whole grains and vegetables) to help regulate blood glucose levels.,,Additionally, some foods that are high in fiber can also affect the absorption of the medication. It's generally recommended to space out the consumption of high-fiber foods and the medication by at least 2-3 hours to avoid any potential interaction.,,Overall, it's important to speak with a healthcare provider or registered dietitian to discuss any specific dietary recommendations when taking Sitagliptin and metformin. They can provide personalized advice based on individual health status and dietary needs.

Drug disease interaction: Sitagliptin 50 mg + metformin 500 mg is a combination medication used to treat type 2 diabetes mellitus. This medication works by improving the body's response to insulin and reducing the amount of glucose produced by the liver.,,When taking Sitagliptin 50 mg + metformin 500 mg, there are certain conditions and medications that may interact with it. One such condition is renal impairment or kidney disease, as the drug is primarily excreted through the kidneys.,,Other medications that may interact with Sitagliptin 50 mg + metformin 500 mg include:

Insulin or other antidiabetic drugs,,Certain blood pressure medications, such as ACE inhibitors and angiotensin II receptor blockers (ARBs),,Corticosteroids,,Thyroid hormone replacement therapy,,Certain antibiotics, such as cimetidine and trimethoprim.

It is important to talk to your doctor or pharmacist before starting any new medications, including over-the-counter drugs and supplements, to avoid potential interactions.

Sitagliptin 50 mg + metformin 500 mg is a combination medication used to treat type 2 diabetes. As with any medication, there are certain contraindications or situations in which it should not be used.,,Some contraindications of Sitagliptin 50 mg + metformin 500 mg include:

Hypersensitivity: People who have a known hypersensitivity to sitagliptin or metformin should not take this medication.,,Severe kidney problems: Sitagliptin 50 mg + metformin 500 mg can cause a rare but serious side effect called lactic acidosis, which is more likely to occur in people with severe kidney problems. Therefore, this medication should not be used in people with severe kidney problems or who have end-stage renal disease.,,Liver problems: This medication should not be used in people with liver problems or who have a history of liver disease.,,Heart failure: Sitagliptin 50 mg + metformin 500 mg should not be used in people with moderate to severe heart failure.,,Metabolic acidosis: This medication should not be used in people with metabolic acidosis, a condition where there is too much acid in the blood.,,Type 1 diabetes: This medication is not recommended for people with type 1 diabetes as it is not effective in treating this condition.

It is important to talk to a doctor or healthcare provider before taking any new medication, including Sitagliptin 50 mg + metformin 500 mg, to ensure it is safe and appropriate for an individual's medical history and current health status.

Store this medicine at room temperature, away from sunlight and moisture.

Sitagliptin 50 mg + metformin 500 mg is a combination medication that is used to treat type 2 diabetes.

The two active ingredients work in different ways to help control blood sugar levels:

Sitagliptin: This medication is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the amount of insulin released by the pancreas and reducing the amount of glucose produced by the liver. This helps to lower blood sugar levels after meals.,,Metformin: This medication is a biguanide that works by reducing the amount of glucose produced by the liver and increasing the body's sensitivity to insulin. This helps to lower fasting blood sugar levels.

The combination of sitagliptin and metformin is often used when metformin alone is not enough to control blood sugar levels or when a patient cannot tolerate a higher dose of metformin.

In summary, Sitagliptin 50 mg + metformin 500 mg is used to:

Lower blood sugar levels in people with type 2 diabetes,,Increase the body's sensitivity to insulin,,Reduce the amount of glucose produced by the liver,,Improve the overall management of type 2 diabetes.