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Medicine Highlights
| Uses | 1- To treat ulcer in stomach and large intestine (Duodenal ulcer) |
| Common Side Effects | 1- Constipation 2- Nausea 3- Vomiting 4- Flatulence 5- Headache 6- Dry mouth 7- Skin Rash |
| Additional Information | Avoid taking alcohol or tobacco with this medicine. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | The medicine should be taken orally |
Oxetacaine + Sucralfate Summary
Oxetacaine and sucralfate are used to treat stomach and intestinal ulcers by providing pain relief and forming a protective barrier over damaged mucosa. Oxetacaine acts as a local anesthetic by blocking nerve signals, while sucralfate coats ulcers, neutralizes acid, and aids healing. Common side effects include constipation, nausea, vomiting, headache, dry mouth, and skin rash, while less common ones may include dizziness, bloating, indigestion, and trouble sleeping. Patients with allergies or diabetes should consult their doctor before use, as it may affect blood sugar levels. This medicine should be stored at room temperature, away from sunlight and moisture. It should be taken as prescribed by a doctor, without exceeding the recommended dose. If a dose is missed, it should be taken as soon as remembered unless it’s close to the next dose. Overdosing may lead to nausea, vomiting, and abdominal pain, requiring medical attention. Alcohol should be avoided, as it may interfere with the medicine’s effects.
Oxetacaine + Sucralfate Uses
Sucralfate and oxetacaine are oral medicine belonging to the class of protectants and anesthetic antacid medicines. It is used for following indications:
- Ulcer in stomach and large intestine
Oxetacaine+ Sucralfate side effect
More Common
- Constipation
- Nausea
- Vomiting
- Flatulence
- Headache
- Dry mouth
- Skin Rash
- Itchiness and skin rash
Less Common
- Back ache
- Bloated
- Constipation
- Diarrhea
- Dizziness or lightheadedness
- Excess air or gas in the stomach or intestines
- Feeling of constant movement of self or surroundings
- Headache
- Hives, itching, skin rash
- Indigestion
- Passing gas
- Sensation of spinning
- Sleepiness
- Stomach cramps
- Trouble sleeping
How Oxetacaine + Sucralfate works
Oxetacaine helps relieve pain in the stomach by numbing the nerves there. Its special structure lets it work well even in the stomach’s acidic environment. As a weak base, it enters the nerve cells easily and blocks the signals that cause pain. Sucralfate is an anti-ulcer drug that works in four ways. First, it prevents the breakdown of water and absorbs an acid called pepsin from the stomach, decreasing its concentration. Second, it forms a gel-like barrier over the ulcer, protecting it from acid damage. Third, it increases mucus secretion from prostaglandin-producing cells. Lastly, it promotes the growth of new cells over the mucus, helping to heal the ulcer.
Safety Measure and Warning
📌 1. Allergy/Hypersensitivity
If you develop symptoms like swelling, redness, or itchiness, you may be allergic to this medicine and should inform your doctor.
📌 2. Diabetes
If you are diabetic, inform your doctor, as this medication may increase blood sugar levels.
Oxetacaine + Sucralfate Interaction with Food Product
Sucralfate and oxetacaine do not interact with any food products, but alcohol should be avoided before and after taking the medicine, as it can increase or decrease the effect of the medicine.
Oxetacaine + Sucralfate Interaction with Other Medicines
Avoid taking sucralfate and oxetacaine with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Storage
- The medicine should be stored at room temperature
- Keep away from sunlight and moisture
- Keep away from the reach of children
Oxetacaine+ Sucralfate Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name-
Sucralfate– Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum
Intake routine/cycle
📌 Daily Dose
Take oxetacaine+ sucralfate exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
📌 Missed Dose
If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
📌 Overdose
If you take more than the recommended dose of sucralfate, you may experience symptoms such as indigestion, nausea, vomiting, and abdominal pain.
FAQ’s
1. 1. What are side effects of oxetacaine ?
➡️ Side effects of oxetacaine include constipation, diarrhea, dizziness, weakness, drowsiness, and headache.
2. 2. Is oxetacaine safe during pregnancy?
➡️ Due to a lack of studies, its safety during pregnancy cannot be confirmed. It is best to inform your doctor about your condition before they prescribe this medicine.
3. 3. How to Take Sucralfate?
➡️ You should take this medicine on an empty stomach, one hour before a meal, to avoid the direct interaction between the ulcer and food. Shake well before using it.
4. 4. What is sucralfate suspension used for?
➡️ It is used to treat stomach and duodenal ulcers (ulcers in the small intestine).
5. 5. Can sucralfate cause constipation?
➡️ Yes, constipation is one of the side effects of sucralfate because it slows down the movement of water and other fluids in the digestive tract, resulting in constipation.
Reference
- Nagashima R. Mechanisms of action of sucralfate. J Clin Gastroenterol. 1981;3(Suppl 2):117-27. PMID: 6798100. Available from.
- Kudaravalli P, Patel P, John S. Sucralfate. [Updated 2024 Feb 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from.
- Kudaravalli P, Patel P, John S. Sucralfate. [Updated 2024 Feb 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from.
- Mayo Clinic. Sucralfate (Oral Route) – Description and Brand Names [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; [cited 2025 Apr 2]. Available from.
