category
Heart
composition
This drug contain Ranolazine (er) 500 mg
workings
Ranolazine is a medication that is used to treat chronic angina, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart. Ranolazine works by blocking the late sodium current in heart muscle cells, which reduces the amount of calcium that enters the cells during each heartbeat. This reduction in calcium entry leads to decreased myocardial tension and oxygen consumption, which can improve blood flow to the heart and relieve angina symptoms.
Ranolazine ER (extended-release) 1000 mg is a once-daily formulation of ranolazine that slowly releases the medication into the bloodstream over an extended period of time, allowing for sustained therapeutic effects. The extended-release formulation helps to maintain a consistent blood concentration of ranolazine throughout the day, which can provide continuous relief from angina symptoms.
usage
Ranolazine is a medication that is primarily used for the treatment of chronic angina pectoris (chest pain). Ranolazine works by reducing the amount of oxygen the heart needs to work properly, which can help reduce the frequency and severity of angina episodes.,,Specifically, ranolazine ER (extended-release) 500 mg is a high dose of the medication that is usually prescribed to patients who have not achieved adequate control of their angina symptoms with lower doses or with other medications.,,It is important to note that ranolazine should not be used to treat acute attacks of angina, as it does not provide immediate relief of chest pain. Rather, it is used as a preventative medication to reduce the frequency and severity of angina attacks over time.,,As with any medication, it is important to follow your healthcare provider's instructions for use, including dosage and frequency, and to report any side effects or concerns.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Nausea,,Dizziness,,Headache,,Constipation,,Vomiting,,Abdominal pain,,Dry mouth,,Irregular heartbeat.
If you experience any of these side effects, inform your doctor. In rare cases, Ranolazine ER may cause more serious side effects, such as:
Allergic reactions (swelling of the face, tongue or throat, difficulty breathing, hives),,Severe dizziness or fainting,,Signs of liver problems (jaundice, dark urine, abdominal pain, nausea, vomiting),,Signs of kidney problems (change in the amount of urine, painful urination, blood in urine).
warnings
Warning: Ranolazine ER is a medication used to treat chronic angina (chest pain). As with any medication, there are potential side effects and warnings to be aware of.,,Some of the most common side effects of ranolazine ER 500 mg include dizziness, headache, constipation, nausea, and vomiting. These side effects are usually mild and go away on their own, but if they persist or become severe, you should speak to your healthcare provider.,,Ranolazine ER can also cause more serious side effects, such as changes in heart rhythm, which can lead to a potentially life-threatening condition called torsades de pointes. This side effect is rare, but it is more common in people who have a history of heart rhythm problems or who are taking certain medications that can also affect the heart rhythm.,,It's important to tell your doctor about any other medications you are taking, including over-the-counter drugs, vitamins, and supplements, as some of them may interact with ranolazine ER and increase the risk of side effects.,,If you experience any symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek medical attention immediately.,,Overall, while ranolazine ER can be an effective treatment for angina, it's important to be aware of the potential side effects and to discuss any concerns with your healthcare provider.
interactions
Drug drug interaction: Ranolazine is a medication used to treat chronic angina. There are several drugs that can interact with ranolazine ER 500mg, including:
Drugs that prolong QT interval: Ranolazine can prolong the QT interval, which is a measure of the electrical activity in the heart. Drugs that also prolong the QT interval, such as amiodarone, quinidine, and sotalol, can increase the risk of abnormal heart rhythms and should be used with caution.,,Strong CYP3A inhibitors: Ranolazine is metabolized by the liver enzyme CYP3A4. Drugs that inhibit CYP3A4, such as ketoconazole, itraconazole, and clarithromycin, can increase the concentration of ranolazine in the blood and increase the risk of side effects.,,Drugs that induce CYP3A: Drugs that induce CYP3A, such as rifampin, phenytoin, and carbamazepine, can decrease the concentration of ranolazine in the blood and reduce its effectiveness.,,Grapefruit juice: Grapefruit juice can also inhibit CYP3A4 and increase the concentration of ranolazine in the blood.
It is important to inform your doctor about all the medications, supplements, and herbal products you are taking before starting ranolazine ER 500mg, to avoid any potential drug interactions.
Drug food interaction: Ranolazine ER is a medication used to treat chronic angina (chest pain) and it works by improving blood flow to the heart. It's important to note that certain foods can interact with medications, either by interfering with the medication's absorption, metabolism, or by increasing the risk of side effects.,,There are no specific foods that interact with ranolazine ER, but it's generally recommended to avoid grapefruit and grapefruit juice while taking this medication. Grapefruit can interfere with the metabolism of many medications, including ranolazine ER, which can lead to increased levels of the drug in the bloodstream and an increased risk of side effects.,,It's also important to avoid alcohol while taking ranolazine ER as it can increase the risk of side effects such as dizziness and lightheadedness. Additionally, high-fat meals may decrease the absorption of ranolazine ER, so it's recommended to take the medication with a low-fat meal or on an empty stomach.,,As always, it's important to talk to your healthcare provider about any questions or concerns you may have about your medication and how to take it properly.
Drug disease interaction: Ranolazine ER (extended-release) is a medication used to treat chronic angina (chest pain) in adults. It works by reducing the amount of oxygen the heart needs to function, thus improving blood flow to the heart.,,Ranolazine may interact with other medications that are used to treat heart conditions, such as beta-blockers or calcium channel blockers. It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements, to avoid any potential drug interactions.,,If you have any concerns about how ranolazine may interact with a specific disease or condition you have, it is best to consult with your doctor or pharmacist. They can provide you with personalized information based on your medical history and help you make an informed decision about your treatment.
contraindications
Ranolazine (er) 500 mg is a medication used to treat chronic angina (chest pain) in adult patients. As with any medication, there are some contraindications or situations where the medication should not be used. Here are some contraindications for ranolazine:
Hypersensitivity: Patients who have a known hypersensitivity to ranolazine or any of its components should not take the medication.,,Liver cirrhosis: Ranolazine is metabolized in the liver, and patients with moderate to severe liver cirrhosis should not take the medication.,,Severe renal impairment: Ranolazine is eliminated from the body through the kidneys, and patients with severe renal impairment (creatinine clearance less than 30 mL/min) should not take the medication.,,Concurrent use of strong CYP3A inhibitors: Ranolazine is metabolized by the CYP3A enzyme system, and concurrent use of strong CYP3A inhibitors, such as ketoconazole or ritonavir, can increase ranolazine levels in the body and should be avoided.,,QT prolongation: Ranolazine can cause QT interval prolongation, a potentially life-threatening arrhythmia. It should be used with caution in patients with a history of QT interval prolongation, or in patients taking medications that can prolong the QT interval, such as antiarrhythmics or some antibiotics.,,It is important to discuss any potential contraindications with your healthcare provider before taking any medication, including ranolazine.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Ranolazine is a medication that is primarily used for the treatment of chronic angina pectoris (chest pain). Ranolazine works by reducing the amount of oxygen the heart needs to work properly, which can help reduce the frequency and severity of angina episodes.,,Specifically, ranolazine ER (extended-release) 500 mg is a high dose of the medication that is usually prescribed to patients who have not achieved adequate control of their angina symptoms with lower doses or with other medications.,,It is important to note that ranolazine should not be used to treat acute attacks of angina, as it does not provide immediate relief of chest pain. Rather, it is used as a preventative medication to reduce the frequency and severity of angina attacks over time.,,As with any medication, it is important to follow your healthcare provider's instructions for use, including dosage and frequency, and to report any side effects or concerns.