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Medicine Highlights
| Uses | 1- To treat indigestion 2- To gastroesophageal reflux disease (Acid reflux) |
| Common Side Effects | 1- Diarrhea 2- Stomach pain 3- Flatulence (gas) 4- Dry mouth 5- Dizziness 6- Headache |
| Additional Information | Avoid consuming grapes, alcohol, and tobacco while taking this medicine. |
| Storage | 1- The medicine should be stored at room temperature 2- Keep away from sunlight and moisture 3- Keep away from the reach of children |
| How to Take This Medicine | The medicine should be taken orally |
Pantoprazole + Domperidone Summary
Pantoprazole 40 mg + Domperidone 10 mg is commonly used to treat indigestion and acid reflux. It helps reduce stomach acid and improves digestion. You might experience mild side effects like headache, gas, or dry mouth. Rarely, it can cause symptoms like dizziness or blurred vision. If you have liver or kidney issues, or if you’re pregnant or breastfeeding, talk to your doctor before starting this medicine. Take it exactly as prescribed-same time every day for best results. Avoid grapefruit, alcohol, tobacco, or cranberry, as they may reduce its effectiveness. If you miss a dose, skip it if the next one is near. In case of overdose, watch out for confusion or shakiness and seek medical help. Store it in a cool, dry place away from kids.
Pantoprazole + Domperidone Uses
Pantoprazole 40 mg and domperidone 10 mg is an oral medicine belonging to the class of proton pump inhibitor and benzimidazole medicines respectively. It is used for following indications:
- Acidity (Gastroesophageal reflux disease)
- Indigestion
How Pantoprazole + Domperidone works
Pantoprazole reduces stomach acid by blocking the acid pump, like putting a cork in a bottle, and starts working in a few hours. Domperidone helps move food through the stomach faster by making stomach muscles contract. It also helps prevent nausea by blocking signals in the brain that cause vomiting. Together, they reduce acid and improve digestion. This makes eating and digestion more comfortable.
Pantoprazole + Domperidone side effects
More Common
- Diarrhea
- Stomach pain
- Flatulence (gas)
- Dry mouth
- Dizziness
- Headache
Less Common
- Loss of balance or muscle control
- Swelling of the mouth
- Breast milk flowing from the nipple
- Blurred vision
- Dry mouth
- Flushed, dry skin
- Fruit-like breath odor
- Increased hunger
- Increased thirst
- Increased urination
- Nausea
- Somach pain
- Sweating
- Trouble breathing
Safety Measures and Warning
📌 1- Allergy/Hypersensitivity
If you have an allergy to domperidone or pantoprazole, inform your doctor immediately to avoid or prevent any complications.
📌 2- Kidney dysfunction
If you have pre-existing kidney disease, inform your physician, as they may adjust the dose or decide not to prescribe the medication.
📌 3- Liver dysfunction
This medicine should be avoided in patients with liver disease, as it can be harmful to the liver.
📌 4- Pregnancy
If you are planning to conceive or are pregnant, inform your doctor. Pantoprazole is not usually recommended during pregnancy due to limited information on its safety.
📌 5- Breastfeeding
Pantoprazole is minimally present in breast milk; however, its effects on breast-fed children are not yet fully understood and require further study.
Directions for use
- Take this medicine exactly as prescribed by your doctor, regularly at the same time each day.
- Do not stop taking this medication without your doctor’s approval, even if you feel better.
- If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it.
Pantoprazole + Domperidone Interaction with Other Medicines
Avoid taking pantoprazole 40 mg + Domperidon 10 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Pantoprazole + Domperidone Interaction with Food Product
Avoid taking domperidone and pantoprazole with grapefruit, grapefruit juice, tobacco, alcohol, or cranberry, as these may alter the effects of the medication.
Pantoprazole + Domperidone Chemical Structure
IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name
Domperidone- 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl) propyl]piperidin-4-yl]-1H-benzimidazol-2-one.
Storage
- The medicine should be stored at room temperature
- Keep away from sunlight and moisture
- Keep away from the reach of children
Intake routine/cycle
📌 Daily dose
Take pantoprazole + domperidone exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
📌 Missed Dose
If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
📌 Overdose
For humans, there is no specific dose established to determine the exact threshold beyond which pantoprazole and domperidone becomes unsafe. However, in cases of overdose, symptoms such as hypoactivity, tremors, difficulty in speaking, disorientation, dizziness and ataxia may occur.
FAQ’s
1. When should I take domperidone?
➡️ Take this medicine before meals, exactly as your doctor told you.
2. Can domperidone cause constipation?
➡️ Yes, it has been proven to cause constipation as a side effect.
3. How much domperidone should I take for lactation?
➡️ To enhance milk secretion, you can take 10 mg of domperidone three times a day. Follow the dosage recommended by your doctor.
4. Which is better, domperidone or ondansetron?
➡️ In a study conducted among children aged 3 months to 5 years, it was found that ondansetron is more effective than domperidone in preventing vomiting.
5. Why is domperidone preferred over metoclopramide?
➡️ Metoclopramide is a medicine that can enter the brain and cause side effects, while domperidone acts around the stomach and has fewer side effects.
6. Is domperidone a painkiller?
➡️ No, domperidone is a medicine that prevents vomiting.
7. Is domperidone used for loose motion?
➡️ Domperidone increases bowel movements and helps the digested food pass through the anus, so it is not used for loose motion.
8. How does domperidone increase breast milk?
➡️ Domperidone increases the production of breast milk by increasing the level of milk producing hormone called prolactin
9. Is domperidone banned in India?
➡️ Domperidone is not banned in India if it is used as a single active ingredient. However, some of its combinations with other medicines are banned in India.
10. Why is pantoprazole taken before food?
➡️ Pantoprazole is taken before food because food delays the absorption of the tablet by approximately three to four hours, which can reduce its effectiveness.
11. Why is pantoprazole given with antibiotics?
➡️ Pantoprazole is given with antibiotics to treat ulcers caused by a bacterium called Helicobacter pylori (H. pylori). The combination helps eradicate the bacteria and promotes ulcer healing.
Reference
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