category
Heart
composition
This drug contain Cinnarizine 20mg+ domperidone 15 mg.
workings
Cinnarizine and Domperidone are two medications that are sometimes prescribed together to treat certain conditions. Let's understand how each of them works and how their combination may be beneficial:,,Cinnarizine (20mg):Cinnarizine is an antihistamine and calcium channel blocker. It is primarily used to treat vestibular disorders, which are conditions affecting the inner ear and balance. Some common vestibular disorders include vertigo, motion sickness, and Meniere's disease. Cinnarizine works by blocking histamine receptors in the inner ear and central nervous system, reducing the sensitivity of the vestibular system and helping to control balance and dizziness issues.
Domperidone (15mg):Domperidone is a dopamine receptor antagonist. It is mainly used to treat nausea and vomiting, particularly in conditions such as gastroesophageal reflux disease (GERD) and functional dyspepsia. Domperidone acts on the dopamine receptors in the upper digestive system, promoting the movement of food through the stomach and preventing nausea and vomiting.
Combination:The combination of Cinnarizine and Domperidone can be useful in some cases. For example, in conditions where both vestibular disorders and nausea/vomiting are present, such as in certain cases of vertigo accompanied by gastrointestinal symptoms or motion sickness with nausea.
Cinnarizine helps manage the vestibular component, reducing dizziness and balance issues, while Domperidone targets the gastrointestinal component, alleviating nausea and vomiting. Together, they can provide comprehensive relief for patients experiencing both types of symptoms.
It's important to note that medications should always be taken under the guidance and prescription of a qualified healthcare professional. They will determine the appropriate dosage and duration of treatment based on the individual's specific condition and medical history. If you or someone you know is experiencing these symptoms, it's best to consult a healthcare provider for a proper evaluation and personalized treatment plan.
usage
Treatment of Vertigo and Motion Sickness: Cinnarizine is an antihistamine with antivertigo properties. It helps to reduce dizziness, vertigo, and motion sickness by acting on the vestibular system in the inner ear. This can be useful for individuals who experience nausea and dizziness during travel or other situations where motion-related issues arise.,,Management of Meniere's Disease: Meniere's disease is a disorder of the inner ear that leads to episodes of vertigo, hearing loss, tinnitus (ringing in the ears), and a feeling of fullness or pressure in the ear. Cinnarizine can be prescribed to alleviate the symptoms associated with Meniere's disease.,,Gastrointestinal Disorders: Domperidone is a dopamine antagonist that acts on the gastrointestinal system. It helps to increase the movement of the stomach and intestines, facilitating the passage of food and preventing issues like nausea and vomiting. Domperidone is commonly used to manage conditions such as nausea, vomiting, indigestion, and gastroesophageal reflux disease (GERD).,,Nausea and Vomiting Prevention: The combination of Cinnarizine and Domperidone can be effective in preventing nausea and vomiting induced by various factors, including medications, infections, and digestive issues.,,Postoperative Nausea and Vomiting: This medication combination may also be prescribed for the prevention and management of nausea and vomiting after surgical procedures.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Drowsiness,,Dry mouth,,Dizziness,,Headache,,Nausea,,Gastrointestinal disturbances (such as constipation or diarrhea),,Weight gain,,Allergic reactions (rare),,Dry mouth,,Dizziness,,Headache,,Gastrointestinal disturbances (such as stomach cramps or diarrhea),,Increased prolactin levels (which may lead to breast enlargement or tenderness in some cases)
warnings
Warning: Cinnarizine 20mg and Domperidone 15mg are two different medications that may be prescribed for various conditions.Cinnarizine is an antihistamine used primarily to treat symptoms of motion sickness, such as nausea, vomiting, and dizziness. It works by reducing the sensitivity of the inner ear to motion. Some common side effects of cinnarizine may include drowsiness, dry mouth, and stomach discomfort.,,Domperidone is a medication that helps to increase the movement of the stomach and intestines, and it is often prescribed to relieve symptoms of nausea and vomiting. It is also sometimes used to enhance milk production in breastfeeding women. Domperidone may cause side effects such as headache, dizziness, and gastrointestinal disturbances.,,If a healthcare professional has prescribed these two medications together, they have likely considered the potential benefits and risks for your specific condition. However, it is essential to be aware of possible drug interactions and to inform your doctor about any other medications you are taking to avoid adverse effects.
interactions
Drug drug interaction: Some potential interactions between Cinnarizine and Domperidone may include:,,Central Nervous System (CNS) Depression: Both Cinnarizine and Domperidone can have mild sedative effects on the central nervous system. Taking them together might increase the risk of excessive sedation and drowsiness.,,Drug Metabolism: These medications may affect the metabolism of other drugs in the body, leading to altered blood levels of certain medications.,,Heart Rhythm: Cinnarizine has been associated with prolongation of the QT interval, which could increase the risk of arrhythmias. When combined with Domperidone, which can also have QT-prolonging effects, there might be an increased risk of abnormal heart rhythms.,,Other Interactions: Cinnarizine and Domperidone might have interactions with other medications, supplements, or medical conditions. It's essential to consider the individual's full medical history and current medication regimen.
Drug food interaction: Cinnarizine and Domperidone are medications used to treat various conditions, including motion sickness, vertigo, and nausea. When taking medications, it's essential to be cautious about potential interactions with certain foods or substances. However, the specific interaction of these medications with food is generally limited.,,Cinnarizine is an antihistamine used to control nausea and vomiting associated with motion sickness. It may cause drowsiness in some individuals. Therefore, it's generally recommended to avoid alcohol and other sedative substances while taking Cinnarizine.,,Domperidone is a medication that helps control nausea and vomiting by increasing the movements or contractions of the stomach and bowel. It does not have significant interactions with food, so it can generally be taken with or without food.
Drug disease interaction: Cinnarizine 20mg + Domperidone 15mg is a combination medication commonly used to treat symptoms associated with motion sickness and vestibular disorders.,,Cinnarizine: It is an antihistamine and calcium channel blocker that is primarily used to prevent and relieve symptoms of motion sickness, such as nausea, vomiting, and dizziness. It works by reducing the sensitivity of the inner ear to motion and changes in position.,,Domperidone: This is a prokinetic agent that helps to increase the movement of the stomach and intestines. It is used to treat nausea and vomiting and is often prescribed to relieve symptoms associated with various gastrointestinal disorders.,,Therefore, the combination of Cinnarizine and Domperidone is particularly effective in treating motion sickness and related symptoms like nausea and vomiting. The interaction between these two drugs is meant to provide a synergistic effect in managing the symptoms and offering relief to the patient.
As with any medication, it's essential to follow the prescribed dosage and consult with a healthcare professional before starting any new treatment, especially if you have pre-existing medical conditions or are taking other medications. They can provide personalized advice and ensure the treatment is safe and appropriate for your specific health situation.
contraindications
Cinnarizine and domperidone are both medications used to treat different conditions, and they are sometimes prescribed together for certain medical conditions. However, there can be contraindications for using this combination in specific situations. A contraindication is a condition or factor that makes the use of a certain medication or treatment unsafe or inadvisable. It means that the potential risks of using the medication outweigh the potential benefits.,,One of the main contraindications for Cinnarizine and Domperidone combination is:
Hypersensitivity or Allergy: If an individual is known to be hypersensitive or allergic to either Cinnarizine or Domperidone, or any of the other ingredients in these medications, they should not take the combination product.,,Other contraindications may include:
Prolactin-releasing Pituitary Tumor (Prolactinoma): Domperidone can increase prolactin levels, which might be problematic for individuals with prolactinomas.,,Gastrointestinal Perforation or Bleeding: Both medications can potentially increase the risk of gastrointestinal perforation or bleeding.,,Parkinson's Disease or Movement Disorders: Domperidone can worsen symptoms in individuals with Parkinson's disease or certain movement disorders.,,Severe Liver or Kidney Dysfunction: Both Cinnarizine and Domperidone are metabolized in the liver and excreted by the kidneys. Severe impairment of these organs can lead to the accumulation of the drugs and adverse effects.,,Cardiac Arrhythmias or QTc Prolongation: Cinnarizine and Domperidone can prolong the QT interval, which may be problematic for individuals with pre-existing cardiac arrhythmias or conditions that predispose them to QTc prolongation.,,It's important to note that this is not an exhaustive list, and there might be other specific contraindications or precautions advised by healthcare professionals based on an individual's medical history and condition.
Always consult with a healthcare provider or pharmacist before starting any new medication or combination of medications to ensure that it is safe and appropriate for your specific health needs. They can review your medical history, assess potential drug interactions, and provide personalized recommendations.
other
Follow the prescribed dosage: Take the medication exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your doctor.,,Take it with or after food: Cinnarizine and Domperidone are often recommended to be taken with or after meals to reduce the risk of stomach upset. Follow the instructions given by your doctor or pharmacist.,,Avoid alcohol: Drinking alcohol while taking medication can increase the risk of side effects or interactions. Check with your healthcare provider if it is safe for you to consume alcohol while on this medication.,,Be cautious with driving and operating machinery: Cinnarizine can cause drowsiness or dizziness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.,,Inform your doctor of medical history: Be sure to provide your healthcare provider with a comprehensive medical history, including any allergies, previous adverse reactions to medications, and any other relevant conditions you may have.,,Watch for potential side effects: While many people may tolerate this medication well, it can cause side effects in some individuals. Common side effects may include drowsiness, headache, dry mouth, and gastrointestinal discomfort. If you experience any severe or persistent side effects, contact your doctor promptly.,,Be cautious with certain medical conditions: Inform your healthcare provider if you have any pre-existing medical conditions, such as liver or kidney problems, Parkinson's disease, or a history of heart issues.,,Avoid self-medication: This combination medication should only be used under the guidance of a healthcare professional. Do not take any other medications, including over-the-counter drugs or herbal supplements, without consulting your doctor or pharmacist.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Treatment of Vertigo and Motion Sickness: Cinnarizine is an antihistamine with antivertigo properties. It helps to reduce dizziness, vertigo, and motion sickness by acting on the vestibular system in the inner ear. This can be useful for individuals who experience nausea and dizziness during travel or other situations where motion-related issues arise.,,Management of Meniere's Disease: Meniere's disease is a disorder of the inner ear that leads to episodes of vertigo, hearing loss, tinnitus (ringing in the ears), and a feeling of fullness or pressure in the ear. Cinnarizine can be prescribed to alleviate the symptoms associated with Meniere's disease.,,Gastrointestinal Disorders: Domperidone is a dopamine antagonist that acts on the gastrointestinal system. It helps to increase the movement of the stomach and intestines, facilitating the passage of food and preventing issues like nausea and vomiting. Domperidone is commonly used to manage conditions such as nausea, vomiting, indigestion, and gastroesophageal reflux disease (GERD).,,Nausea and Vomiting Prevention: The combination of Cinnarizine and Domperidone can be effective in preventing nausea and vomiting induced by various factors, including medications, infections, and digestive issues.,,Postoperative Nausea and Vomiting: This medication combination may also be prescribed for the prevention and management of nausea and vomiting after surgical procedures.