category
Digestive
composition
This drug contain Esomeprazole 40 mg (ec)+ itopride (sr) 150 mg.
workings
Esomeprazole and itopride are two different medications that are often prescribed together for the treatment of certain gastrointestinal conditions. Let's understand how each of these medications works:
Esomeprazole 40 mg (EC): Esomeprazole is a proton pump inhibitor (PPI) used to reduce stomach acid production. It is commonly prescribed to treat conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. Esomeprazole works by selectively inhibiting the proton pumps in the stomach lining, which are responsible for producing gastric acid. By blocking these pumps, esomeprazole effectively reduces the amount of acid produced, leading to decreased acidity in the stomach and providing relief from symptoms associated with excessive acid, such as heartburn, acid reflux, and ulcer pain.
The "EC" in the prescription refers to "enteric-coated," which means that the medication is designed to dissolve in the intestine rather than the stomach. This allows it to be better absorbed and provides a more sustained release of the medication.,,Itopride (SR) 150 mg: Itopride is a prokinetic agent used to improve gastrointestinal motility, particularly in the upper digestive tract. It is commonly prescribed for conditions such as functional dyspepsia, non-ulcer dyspepsia, and gastroparesis. Itopride works by blocking certain receptors (dopamine D2 receptors) in the gut, which results in an increase in acetylcholine levels. Acetylcholine is a neurotransmitter that plays a key role in stimulating the movement of the digestive tract muscles and promoting the passage of food through the gastrointestinal tract.
By increasing acetylcholine levels, itopride enhances the motility of the upper digestive system, helping to move food and stomach contents more efficiently, reducing symptoms like bloating, early satiety, and discomfort after meals.
Combining Esomeprazole and Itopride: The combination of esomeprazole and itopride is often prescribed to address both the excessive acid production and impaired gastrointestinal motility associated with certain conditions like GERD, functional dyspepsia, or acid-related disorders with delayed gastric emptying. By reducing stomach acid production and improving the motility of the upper digestive system, this combination can provide comprehensive relief from the symptoms caused by these conditions.
It's important to note that medication should only be taken as prescribed by a qualified healthcare professional. If you have any concerns or questions about your prescribed medications or their effects, always consult your doctor or pharmacist for personalized advice and guidance.
usage
Esomeprazole 40 mg (EC) and Itopride (SR) 150 mg are medications used to treat certain gastrointestinal conditions. Let's look at their uses separately:
Esomeprazole 40 mg (EC): Esomeprazole is a proton pump inhibitor (PPI) that helps reduce stomach acid production. It is commonly prescribed for the following conditions:,,Gastroesophageal reflux disease (GERD): Esomeprazole is effective in treating the symptoms of GERD, such as heartburn, acid regurgitation, and chest pain caused by stomach acid flowing back into the esophagus.,,Peptic ulcers: Esomeprazole is used to promote healing and prevent recurrence of stomach or duodenal ulcers, which are open sores that can develop on the lining of the stomach or the upper part of the small intestine.,,Helicobacter pylori eradication: Esomeprazole is sometimes used in combination with antibiotics to eradicate H. pylori, a bacterium associated with the development of peptic ulcers.,,Zollinger-Ellison syndrome: This is a rare condition where tumors in the pancreas or duodenum cause excessive production of stomach acid. Esomeprazole can help manage the symptoms in these cases.,,Itopride (SR) 150 mg:,,Itopride is a prokinetic agent that enhances the motility of the gastrointestinal tract. It is commonly prescribed for the treatment of functional gastrointestinal disorders, including:,,Non-ulcer dyspepsia: Itopride is used to alleviate symptoms like bloating, early satiety, and discomfort in the upper abdomen, which are often associated with functional dyspepsia.,,Gastroparesis: This condition is characterized by delayed emptying of the stomach, leading to symptoms like nausea, vomiting, and feeling full quickly. Itopride helps improve stomach emptying and reduce these symptoms.,,Gastroesophageal reflux disease (GERD): In some cases, Itopride may be used in combination with PPIs like Esomeprazole to manage the symptoms of GERD by promoting stomach emptying and reducing reflux.
It's important to note that the use of medications should always be prescribed and supervised by a qualified healthcare professional. They will consider the patient's medical history, specific condition, and other factors to determine the appropriate dosage and duration of treatment. If you have any concerns or questions about these medications, please consult your healthcare provider.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Headache,,Nausea,,Diarrhea,,Abdominal pain or discomfort,,Constipation,,Flatulence (gas),,Dry mouth.
Rare but more serious side effects may include:Allergic reactions (rash, itching, swelling, severe dizziness, difficulty breathing),,Severe diarrhea (which may be a sign of a bacterial infection called Clostridium difficile-associated diarrhea),,Bone fractures, especially with long-term use,,Hypomagnesemia (low magnesium levels in the blood),,Increased risk of certain infections due to reduced stomach acid.
Common side effects of Itopride (SR):,,Diarrhea,,Nausea,,Vomiting,,Headache,,Dizziness,,Abdominal pain or discomfort,,Constipation.
Less common side effects include:,,Rash or skin reactions,,Increased heart rate (tachycardia) or irregular heart rhythms (arrhythmias).
warnings
Warning: Esomeprazole 40 mg (EC):Esomeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid. It is commonly prescribed to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The "EC" in the medication name typically stands for "enteric-coated," which means the tablets are designed to release the medication in a specific part of the gastrointestinal tract.
Potential side effects of Esomeprazole may include headache, nausea, abdominal pain, diarrhea, and dizziness. In rare cases, it can be associated with more severe side effects, so it's important to follow your doctor's instructions and report any unusual symptoms.
Itopride (SR) 150 mg: Itopride is a prokinetic agent used to improve gastrointestinal motility, particularly in conditions like dyspepsia or delayed gastric emptying. The "SR" in the medication name usually indicates "sustained-release," meaning the medication is released gradually over time.
Common side effects of Itopride may include diarrhea, headache, dizziness, and mild gastrointestinal discomfort. As with any medication, some individuals may experience adverse reactions, so it's essential to inform your healthcare provider if you notice any concerning symptoms.
interactions
Drug drug interaction: There are some potential drug interactions between Esomeprazole and Itopride with other medications, but the specific interactions can vary depending on the individual's medical history and other medications they are taking. For example:
Clopidogrel: Esomeprazole may reduce the antiplatelet effect of clopidogrel, a drug used to prevent blood clots. This interaction could increase the risk of cardiovascular events.,,Citalopram, Escitalopram: Co-administration of Esomeprazole and these antidepressants can increase their blood levels, potentially leading to adverse effects.,,Diazepam: There is a possibility of increased blood levels of diazepam when taken with Esomeprazole, potentially leading to enhanced sedative effects.,,Warfarin: Esomeprazole may interact with warfarin, an anticoagulant, and increase the risk of bleeding.,,Other Acid-Suppressing Drugs: Co-administration of multiple acid-suppressing drugs (like other proton pump inhibitors or H2 blockers) may not provide additional benefits and can increase the risk of adverse effects.
Drug food interaction: Esomeprazole 40 mg (EC) and itopride (SR) 150 mg are medications used to treat gastrointestinal conditions. Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, and itopride is a prokinetic agent that helps improve the motility of the digestive system.,,When taking medications like these, it's essential to be cautious about certain foods that may interact with them and potentially affect their effectiveness or cause unwanted side effects. However, specific interactions between these medications and particular foods are not well-documented.,,Generally, it's advisable to take Esomeprazole and itopride on an empty stomach, about 30 minutes to 1 hour before meals, to maximize their effects. This allows the medications to be absorbed properly without interference from food.
Drug disease interaction: Esomeprazole is a proton pump inhibitor (PPI) used to reduce stomach acid production and is commonly prescribed for the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders.,,Itopride is a prokinetic agent used to enhance gastrointestinal motility and is often prescribed for conditions like functional dyspepsia, gastroparesis, and other motility disorders of the upper gastrointestinal tract.,,The combination of Esomeprazole 40 mg (EC) and Itopride (SR) 150 mg is commonly prescribed to manage various gastrointestinal disorders, such as GERD with associated dyspeptic symptoms like bloating, early satiety, and postprandial fullness.
So, the diseases that these medications interact with are GERD, functional dyspepsia, peptic ulcers, gastroparesis, and other acid-related and motility disorders of the upper gastrointestinal tract. As with any medication, it's essential to follow your doctor's prescription and advice regarding the use of these medications and any potential side effects or interactions. Always consult a healthcare professional for personalized medical advice.
contraindications
Allergy or hypersensitivity: Individuals who have a known allergy or hypersensitivity to Esomeprazole, Itopride, or any of the other ingredients in these medications should avoid using them.,,Severe liver or kidney disease: Both Esomeprazole and Itopride are primarily metabolized in the liver and excreted through the kidneys. Severe liver or kidney impairment could affect the clearance of these drugs and may lead to increased drug levels in the body, potentially causing adverse effects.,,Cardiac issues: There have been rare reports of cardiac arrhythmias associated with Itopride use. Therefore, caution may be required in patients with pre-existing heart conditions.,,Gastrointestinal bleeding or obstruction: Esomeprazole may mask symptoms of underlying gastrointestinal conditions like bleeding or obstruction. Itopride's prokinetic effect could potentially worsen some gastrointestinal conditions, so its use should be carefully evaluated in such cases.,,Pregnancy and breastfeeding: Safety data may be limited for the use of this combination during pregnancy and breastfeeding. It's essential to consult a healthcare professional before taking these medications if pregnant or breastfeeding.,,Interactions with other medications: Certain drugs may interact with Esomeprazole or Itopride, leading to adverse effects or reduced efficacy. Inform your doctor about all the medications you are taking to ensure there are no potential interactions.
other
Follow Prescription Guidelines: Take Esomeprazole and Itopride exactly as prescribed by your healthcare professional. Follow the recommended dosage, frequency, and duration of the treatment.,,Allergies and Medical Conditions: Inform your doctor about any known allergies or medical conditions you have before starting this medication. They will assess if it is safe for you to take Esomeprazole and Itopride.,,Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor if it is safe to use these medications.,,Interactions: Inform your healthcare provider about all other medications, supplements, or herbal products you are taking to avoid potential drug interactions.,,Side Effects: Be aware of the possible side effects and what to do if you experience any adverse reactions. Common side effects may include headache, dizziness, diarrhea, or constipation.,,Driving and Machinery: Both Esomeprazole and Itopride can cause dizziness in some individuals. If you experience this, avoid driving or operating heavy machinery until you know how the medication affects you.,,Avoid Alcohol and Tobacco: Alcohol and tobacco can worsen certain gastrointestinal conditions. It's advisable to avoid or limit their consumption while taking these medications.,,Long-term Use: Esomeprazole is a proton pump inhibitor (PPI) used to reduce stomach acid production. Long-term use of PPIs may have some risks, so it's essential to discuss the duration of treatment with your healthcare provider.,,Storage: Store the medication as directed on the packaging, and keep it out of reach of children and pets.,,Missed Dose: If you miss a dose, take it as soon as you remember. However, if it's close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.,,Overdose: In case of an overdose or accidental ingestion of more than the prescribed dose, seek medical attention immediately or contact your local poison control center.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Esomeprazole 40 mg (EC) and Itopride (SR) 150 mg are medications used to treat certain gastrointestinal conditions. Let's look at their uses separately:
Esomeprazole 40 mg (EC): Esomeprazole is a proton pump inhibitor (PPI) that helps reduce stomach acid production. It is commonly prescribed for the following conditions:,,Gastroesophageal reflux disease (GERD): Esomeprazole is effective in treating the symptoms of GERD, such as heartburn, acid regurgitation, and chest pain caused by stomach acid flowing back into the esophagus.,,Peptic ulcers: Esomeprazole is used to promote healing and prevent recurrence of stomach or duodenal ulcers, which are open sores that can develop on the lining of the stomach or the upper part of the small intestine.,,Helicobacter pylori eradication: Esomeprazole is sometimes used in combination with antibiotics to eradicate H. pylori, a bacterium associated with the development of peptic ulcers.,,Zollinger-Ellison syndrome: This is a rare condition where tumors in the pancreas or duodenum cause excessive production of stomach acid. Esomeprazole can help manage the symptoms in these cases.,,Itopride (SR) 150 mg:,,Itopride is a prokinetic agent that enhances the motility of the gastrointestinal tract. It is commonly prescribed for the treatment of functional gastrointestinal disorders, including:,,Non-ulcer dyspepsia: Itopride is used to alleviate symptoms like bloating, early satiety, and discomfort in the upper abdomen, which are often associated with functional dyspepsia.,,Gastroparesis: This condition is characterized by delayed emptying of the stomach, leading to symptoms like nausea, vomiting, and feeling full quickly. Itopride helps improve stomach emptying and reduce these symptoms.,,Gastroesophageal reflux disease (GERD): In some cases, Itopride may be used in combination with PPIs like Esomeprazole to manage the symptoms of GERD by promoting stomach emptying and reducing reflux.
It's important to note that the use of medications should always be prescribed and supervised by a qualified healthcare professional. They will consider the patient's medical history, specific condition, and other factors to determine the appropriate dosage and duration of treatment. If you have any concerns or questions about these medications, please consult your healthcare provider.