category
Urinary system
composition
This drug contain Mirabegron (er) 50 mg.
workings
Mirabegron is a medication used to treat overactive bladder (OAB) and works as a selective beta-3 adrenergic receptor agonist. It is commonly prescribed under the brand name Myrbetriq (ER stands for extended-release). Let's break down how Mirabegron works:
Overactive Bladder (OAB): OAB is a condition characterized by the frequent and sudden urge to urinate, often accompanied by urinary incontinence (the involuntary loss of urine). This happens due to the involuntary contractions of the detrusor muscle in the bladder, leading to an urgent need to urinate even when the bladder is not full.
Beta-3 Adrenergic Receptors: Mirabegron specifically targets and activates beta-3 adrenergic receptors in the detrusor muscle of the bladder. These receptors are part of the sympathetic nervous system, which controls various involuntary functions in the body.,,Relaxation of Detrusor Muscle: When Mirabegron binds to and activates the beta-3 adrenergic receptors, it causes relaxation of the detrusor muscle in the bladder. This relaxation reduces the spontaneous contractions of the bladder, helping to increase its storage capacity and reducing the frequent and urgent need to urinate.,,Increased Bladder Capacity: By reducing the frequency of involuntary contractions and increasing the bladder's storage capacity, Mirabegron helps control the symptoms of overactive bladder, such as urgency and urinary incontinence.
It's essential to follow your doctor's instructions and dosage recommendations while taking Mirabegron or any medication. If you have any specific questions or concerns about this medication, it's best to consult your healthcare provider for personalized advice.
usage
Mirabegron is a medication that belongs to a class of drugs known as beta-3 adrenergic agonists. It is primarily used to treat overactive bladder (OAB) and its associated symptoms, such as urinary urgency, frequency, and incontinence. Here are some specific uses of Mirabegron (ER) 50 mg:
Overactive Bladder (OAB): Mirabegron is approved for the treatment of overactive bladder in adults. OAB is a condition characterized by an uncontrollable urge to urinate, frequent urination, and sometimes involuntary leakage of urine.,,Urinary Urgency: Mirabegron helps to reduce the sudden and intense urge to urinate, allowing individuals with OAB to better control their bladder function.,,Urinary Frequency: People with OAB often experience increased urinary frequency, which can disrupt daily activities. Mirabegron helps to reduce the number of times one needs to urinate.,,Urinary Incontinence: In some cases of OAB, individuals may experience episodes of urinary incontinence, where they leak urine involuntarily. Mirabegron can help manage and reduce these episodes.,,Enhanced Bladder Storage: Mirabegron works by relaxing the detrusor muscle of the bladder, which increases the bladder's storage capacity, thus reducing the need for frequent urination.,,Extended-Release Formulation: The "ER" in Mirabegron (ER) 50 mg stands for "extended-release." This means that the medication is formulated to release the active ingredient gradually over time, allowing for once-daily dosing. The extended-release formulation provides sustained therapeutic effects throughout the day.
It's important to note that Mirabegron is available in different dosages, and the appropriate dose prescribed by a healthcare professional may vary depending on individual needs and medical conditions. As with any medication, it is essential to follow your healthcare provider's instructions and report any side effects or concerns during treatment.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Headache: Some people may experience mild to moderate headaches while taking Mirabegron.,,Nausea: Feeling nauseous or having an upset stomach is a possible side effect.,,Dizziness: Mirabegron can cause dizziness or lightheadedness, especially when standing up quickly.,,Increased blood pressure: Some individuals may experience a slight increase in blood pressure while on this medication.,,Urinary tract infection (UTI): There might be an increased risk of UTIs in some patients.,,Common cold symptoms: Mirabegron use may be associated with symptoms similar to the common cold, such as a runny or stuffy nose.,,Constipation: Some people may experience difficulty passing stools or infrequent bowel movements.,,Diarrhea: In some cases, diarrhea may occur as a side effect.,,Dry mouth: Mirabegron can lead to a reduction in saliva production, causing dryness in the mouth.,,Fatigue: Feeling tired or experiencing a lack of energy is a possible side effect.,,Back pain: Some individuals may experience back pain while taking this medication.,,Joint pain: Mirabegron might cause joint discomfort or pain in some patients.
warnings
Warning: Mirabegron is a medication used to treat overactive bladder (OAB) symptoms such as frequent urination, urgency, and incontinence. It works by relaxing the bladder's smooth muscle, increasing the bladder's storage capacity and reducing the urge to urinate.,,As with any medication, there are potential side effects and warnings associated with Mirabegron. Common side effects may include:
Headache,,Increased blood pressure,,Common cold symptoms (e.g., stuffy nose, sore throat),,Urinary tract infection (UTI),,Constipation,,Diarrhea,,Nausea.
More severe side effects may occur, although they are rare. If you experience any of the following, contact your healthcare provider immediately:
Severe allergic reactions (e.g., rash, itching, swelling of the face, tongue, or throat, severe dizziness, difficulty breathing),,Chest pain or irregular heartbeat,,Severe dizziness or fainting,,Painful or difficult urination.
It is important to inform your healthcare provider about your medical history, especially if you have a history of high blood pressure, liver problems, kidney problems, or any heart-related issues, as these conditions may impact the use of Mirabegron.,,Mirabegron may also interact with other medications, so it is crucial to provide a comprehensive list of all the medications, supplements, and herbal products you are taking to your healthcare provider to avoid any potential drug interactions.,,This information is not exhaustive, and it is essential to follow your healthcare provider's guidance and the information provided with the medication carefully to ensure safe and effective use of Mirabegron. Always consult your doctor or pharmacist if you have any questions or concerns about your medication.
interactions
Drug drug interaction: Mirabegron is a medication used to treat overactive bladder. When taking any medication, including Mirabegron, it's essential to be aware of potential drug interactions, as they can lead to unwanted side effects or reduce the effectiveness of the medications involved.,,Some drugs that may interact with Mirabegron include:,,Monoamine Oxidase Inhibitors (MAOIs): Combining Mirabegron with MAOIs may increase blood pressure and the risk of hypertensive crisis.,,CYP3A4 Inhibitors: Drugs that inhibit the CYP3A4 enzyme in the liver can potentially increase the levels of Mirabegron in the bloodstream, leading to a higher risk of side effects.,,CYP2D6 Inhibitors: Similarly, drugs that inhibit the CYP2D6 enzyme may increase the levels of Mirabegron, potentially causing adverse effects.,,Beta-Blockers: The combination of Mirabegron with beta-blockers may counteract the effects of each other on heart rate and blood pressure.,,Anticholinergic Drugs: Mirabegron may have additive effects with other drugs that have anticholinergic properties, possibly increasing the risk of side effects like dry mouth, constipation, and urinary retention.,,Digoxin: Mirabegron may increase the levels of digoxin, a drug used to treat heart conditions, so caution and monitoring may be necessary.,,Medications that cause QT prolongation: Combining Mirabegron with other drugs that can prolong the QT interval may increase the risk of serious cardiac arrhythmias.
Again, this list is not exhaustive, and there might be other drugs that interact with Mirabegron. Always inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Mirabegron or any new medication to ensure your safety and well-being. They can provide personalized advice and adjust your treatment plan accordingly.
Drug food interaction: Mirabegron is a medication used to treat overactive bladder (OAB). While there are no specific foods that are known to interact with Mirabegron, it's essential to be mindful of certain substances that can exacerbate the side effects of the medication or impact its effectiveness.,,Caffeine: Consuming caffeine-rich foods and beverages, such as coffee, tea, energy drinks, and some sodas, may worsen the symptoms of overactive bladder, which could counteract the effects of Mirabegron.,,Alcohol: Alcohol can irritate the bladder and increase the frequency of urination, which might counteract the benefits of Mirabegron in treating OAB symptoms.,,Spicy foods and acidic foods: These foods might irritate the bladder in some people, potentially making OAB symptoms worse.,,Citrus fruits: Some people with overactive bladder may find that citrus fruits, like oranges and grapefruits, irritate their bladder.,,Carbonated beverages: The carbonation in sodas and some sparkling waters might cause discomfort in individuals with overactive bladder.
It's important to note that these interactions or effects can vary from person to person. If you have concerns about your diet while taking Mirabegron or if you experience any adverse effects, it's best to consult your healthcare provider or a registered dietitian for personalized advice and recommendations. They can provide guidance tailored to your specific medical history and needs.
Drug disease interaction: Mirabegron is a medication primarily used to treat overactive bladder (OAB) symptoms such as frequent urination, urgency, and urinary incontinence. It works by relaxing the smooth muscles of the bladder, which helps increase the bladder's storage capacity and reduces the frequency of contractions.
Mirabegron does not interact with a specific disease, but it may interact with other medications or medical conditions. For example, it can have interactions with drugs metabolized by certain enzymes in the liver, which may affect its effectiveness or increase the risk of side effects. It's essential for individuals taking Mirabegron to inform their healthcare provider about any other medications, supplements, or medical conditions they have to ensure safety and optimize treatment.
As with any medication, it's crucial to follow your doctor's advice and prescription guidelines to avoid potential interactions and to monitor for any adverse effects while taking Mirabegron. If you have any concerns or questions about this medication, please consult your healthcare provider for personalized advice.
contraindications
That being said, here are some common contraindications and precautions associated with Mirabegron:
Allergy or hypersensitivity: Individuals with a known allergy to Mirabegron or any of its components should not take this medication.,,Severe liver impairment: Patients with severe liver impairment may not be able to effectively metabolize Mirabegron, leading to potential adverse effects.,,Severe kidney impairment: Mirabegron may be contraindicated or require dose adjustment in individuals with severe kidney impairment.,,Urinary retention: Mirabegron is not recommended for use in patients with urinary retention, as it may exacerbate the condition.,,Uncontrolled hypertension (high blood pressure): Mirabegron can cause an increase in blood pressure, so it should be used with caution in individuals with uncontrolled hypertension or severe cardiovascular conditions.,,Certain medications: There may be interactions between Mirabegron and other medications, such as CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) or CYP2D6 inhibitors (e.g., fluoxetine, paroxetine).,,Pregnancy and breastfeeding: The safety of Mirabegron during pregnancy and breastfeeding has not been extensively studied, so it should be used with caution in these situations.
other
Mirabegron is a medication used to treat overactive bladder (OAB) symptoms, such as frequent urination, urgency, and incontinence. Here are some safety advice and important considerations for taking Mirabegron ER (extended-release) 50 mg:
Follow Doctor's Instructions: Always take the medication exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider.,,Allergies and Medical Conditions: Inform your doctor about any allergies you have, especially if you have a known hypersensitivity to Mirabegron or any of its ingredients. Also, disclose any other medical conditions you may have, especially if you have severe liver or kidney problems.,,Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Mirabegron with your doctor. It is essential to weigh the potential benefits against the risks during pregnancy and breastfeeding.,,Interactions with Other Medications: Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications may interact with Mirabegron and cause adverse effects.,,Avoid Alcohol and Certain Beverages: Alcohol and beverages containing caffeine can aggravate overactive bladder symptoms. Limiting or avoiding these substances may help manage OAB symptoms effectively.,,Driving and Operating Machinery: Mirabegron may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.,,Stay Hydrated: Drink enough water throughout the day to maintain good overall bladder health. Adequate hydration can help prevent urinary tract infections and manage OAB symptoms.,,Report Side Effects: If you experience any unusual or severe side effects while taking Mirabegron, such as difficulty breathing, rash, swelling, or chest pain, seek immediate medical attention and stop taking the medication.,,Storage: Keep Mirabegron ER in its original container, away from moisture and direct sunlight. Follow the storage instructions provided by your pharmacist.,,Missed Dose: If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Mirabegron is a medication that belongs to a class of drugs known as beta-3 adrenergic agonists. It is primarily used to treat overactive bladder (OAB) and its associated symptoms, such as urinary urgency, frequency, and incontinence. Here are some specific uses of Mirabegron (ER) 50 mg:
Overactive Bladder (OAB): Mirabegron is approved for the treatment of overactive bladder in adults. OAB is a condition characterized by an uncontrollable urge to urinate, frequent urination, and sometimes involuntary leakage of urine.,,Urinary Urgency: Mirabegron helps to reduce the sudden and intense urge to urinate, allowing individuals with OAB to better control their bladder function.,,Urinary Frequency: People with OAB often experience increased urinary frequency, which can disrupt daily activities. Mirabegron helps to reduce the number of times one needs to urinate.,,Urinary Incontinence: In some cases of OAB, individuals may experience episodes of urinary incontinence, where they leak urine involuntarily. Mirabegron can help manage and reduce these episodes.,,Enhanced Bladder Storage: Mirabegron works by relaxing the detrusor muscle of the bladder, which increases the bladder's storage capacity, thus reducing the need for frequent urination.,,Extended-Release Formulation: The "ER" in Mirabegron (ER) 50 mg stands for "extended-release." This means that the medication is formulated to release the active ingredient gradually over time, allowing for once-daily dosing. The extended-release formulation provides sustained therapeutic effects throughout the day.
It's important to note that Mirabegron is available in different dosages, and the appropriate dose prescribed by a healthcare professional may vary depending on individual needs and medical conditions. As with any medication, it is essential to follow your healthcare provider's instructions and report any side effects or concerns during treatment.