category
Brain
composition
This drug contain Propranolol 40mg (sr)+ flunarizine 10 mg.
workings
Propranolol and flunarizine are both medications commonly used to treat certain medical conditions, including migraine headaches and various cardiovascular conditions. Let's take a closer look at each medication and how they work:
Propranolol (40mg SR): Propranolol is a beta-blocker medication that primarily affects the beta-adrenergic receptors in the body. These receptors are part of the sympathetic nervous system, which is responsible for the body's "fight or flight" response. By blocking these receptors, propranolol reduces the effects of adrenaline and other stress hormones, leading to various therapeutic effects.
In the context of migraine treatment, propranolol is believed to work by relaxing and widening the blood vessels in the brain. It also reduces the sensitivity of blood vessels to triggers that may cause migraines. Additionally, propranolol may have a calming effect on the central nervous system, which can help prevent migraines triggered by stress and anxiety.
The "SR" in propranolol 40mg SR stands for "sustained-release," meaning the medication is formulated to release the drug slowly over time, maintaining a more consistent blood level, and potentially allowing for once-daily dosing.
Flunarizine (10mg): Flunarizine belongs to a class of medications known as calcium channel blockers. It works by blocking calcium channels in certain cells, including those in blood vessels and the brain. By inhibiting calcium influx into these cells, flunarizine helps to relax and widen blood vessels, which can be beneficial in the prevention of migraines and reducing blood pressure.
For migraine prophylaxis, flunarizine is thought to reduce the excitability of neurons in the brain and decrease the release of certain neurotransmitters, such as serotonin and histamine, which are involved in migraine pathophysiology.
Combining Propranolol and Flunarizine: The combination of propranolol and flunarizine may be prescribed in some cases for certain individuals who suffer from severe or treatment-resistant migraines. The two medications work synergistically to relax blood vessels in the brain, prevent migraines, and potentially reduce the frequency and severity of headache episodes.
It's important to note that both propranolol and flunarizine can have side effects and interactions with other medications. It is crucial to take these medications only under the guidance and prescription of a qualified healthcare professional who can determine the appropriate dosage and monitor for any adverse effects. If you are considering this medication combination or have any questions or concerns, please consult your doctor.
usage
Propranolol 40mg (SR) and flunarizine 10mg are two different medications commonly used to manage certain medical conditions. Here's a brief overview of their uses:
Propranolol 40mg (SR): Propranolol is a beta-blocker medication that is primarily used to treat various cardiovascular conditions. Some common uses include:
a. Hypertension (High blood pressure): Propranolol can help lower blood pressure, reducing the strain on the heart and blood vessels.,,b. Angina: It can be prescribed to manage chest pain caused by reduced blood flow to the heart.,,c. Arrhythmias: Propranolol is used to control irregular heart rhythms.,,d. Anxiety and performance anxiety: The medication is sometimes used off-label to manage situational anxiety and performance anxiety, as it can reduce physical symptoms like rapid heartbeat and trembling.,,e. Migraine prophylaxis: Propranolol can be effective in preventing migraines in some individuals.
Flunarizine 10mg:Flunarizine is a calcium channel blocker primarily used for the prophylaxis (prevention) of migraines. It works by reducing the hyperexcitability of nerve cells and dilating blood vessels in the brain, which can help prevent the onset of migraines.
The combination of propranolol and flunarizine may be prescribed by healthcare professionals to manage certain types of migraines and headaches that are not well-controlled by either medication alone. This combination can have a synergistic effect and may provide better relief for some individuals.
As with any medication, it is essential to follow your doctor's advice and take them as prescribed. If you have any questions or concerns about these medications, make sure to discuss them with your healthcare provider.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Drowsiness or fatigue: Both medications can cause drowsiness and a feeling of tiredness, especially when taken together. It is advised not to drive or operate heavy machinery until you know how these medications affect you.,,Dizziness or lightheadedness: These medications can cause a drop in blood pressure, leading to feelings of dizziness or lightheadedness, particularly when changing positions (e.g., going from sitting to standing).,,Gastrointestinal issues: Propranolol and flunarizine can lead to digestive problems like nausea, vomiting, or diarrhea in some individuals.,,Cold hands and feet: Beta-blockers like propranolol can reduce blood flow to the extremities, causing cold hands and feet in some people.,,Sleep disturbances: These medications might affect sleep patterns in some individuals, leading to insomnia or disrupted sleep.,,Weight gain: Both propranolol and flunarizine have been associated with weight gain in certain cases.,,Depression or mood changes: Some people may experience changes in mood, including depression, while taking these medications.,,Sexual dysfunction: Beta-blockers can sometimes lead to sexual problems, such as decreased libido or difficulty achieving/maintaining an erection.,,Allergic reactions: Although rare, some individuals may develop an allergic reaction to these medications, which could present with symptoms like skin rash, itching, or difficulty breathing.,,Bradycardia (slow heart rate): Propranolol, as a beta-blocker, can slow down the heart rate, and when combined with flunarizine, it may lead to further reductions in heart rate.
warnings
Warning: Propranolol 40mg (SR):Propranolol is a beta-blocker medication used to treat various conditions such as hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. It is also used to manage symptoms associated with anxiety, including performance anxiety and some forms of tremor. The "SR" likely stands for "sustained-release," which means the medication is formulated to release gradually over time, providing a longer duration of action.
Common side effects of propranolol may include dizziness, fatigue, cold hands and feet, slow heart rate, and upset stomach. Less common but more serious side effects may include trouble breathing, severe dizziness, fainting, and signs of depression. Do not stop taking propranolol suddenly, as it may cause withdrawal symptoms or worsen certain medical conditions.
Flunarizine 10 mg:Flunarizine is an antihistamine and calcium channel blocker that is sometimes used to prevent migraines and manage vertigo and vestibular disorders. Its exact mechanism of action in migraine prevention is not entirely understood, but it is believed to involve the relaxation of blood vessels and reducing the excitability of neurons.,,Flunarizine may cause side effects such as drowsiness, weight gain, and extrapyramidal symptoms (movement disorders). It is important not to drive or operate heavy machinery if you experience significant drowsiness while taking this medication.
Again, it is crucial to consult a healthcare professional about the specific warning labels, interactions, and contraindications for these medications, as individual medical histories and conditions can impact how these drugs affect you. Always follow your doctor's instructions and inform them of any other medications or supplements you are taking to avoid potential drug interactions.
interactions
Drug drug interaction: Propranolol is a beta-blocker that is primarily used to treat conditions like hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. It may also be prescribed for anxiety and migraines.,,Flunarizine is a calcium channel blocker primarily used to prevent migraines and to manage certain balance disorders.,,When taking multiple medications, there is a possibility of drug interactions. The combination of propranolol and flunarizine might cause additive effects on blood pressure and heart rate, which can lead to low blood pressure (hypotension) or other adverse effects.,,Again, it's essential to consult with a healthcare professional, such as a doctor or pharmacist, who has access to your complete medical history and can provide personalized advice regarding any potential drug interactions and the appropriate dosages of medications for your specific condition. They can also monitor your progress and adjust the treatment plan accordingly to ensure your safety and well-being.
Drug food interaction: Propranolol is a beta-blocker used to treat various conditions, including high blood pressure and heart-related issues. Flunarizine is an anti-migraine medication. Neither of these medications is known to have significant interactions with specific foods.,,However, it's always a good idea to follow some general guidelines when taking medications:,,Consistency: If you have been taking these medications with a particular type of food (e.g., always with a meal or on an empty stomach), try to maintain that consistency.,,Avoid Grapefruit: While propranolol and flunarizine are not specifically affected by grapefruit, it's wise to avoid consuming large amounts of grapefruit or grapefruit juice. Grapefruit can interact with many medications and affect their metabolism in the liver, potentially leading to higher-than-expected blood levels of the drug.,,Consult with Healthcare Provider: If you have any concerns about food interactions or if you are taking other medications or have specific health conditions, it's best to consult with your healthcare provider or pharmacist. They can offer personalized advice based on your medical history and the specific medications you are taking.,,Always follow the prescribed dosage and instructions provided by your healthcare professional, and inform them about any other medications or supplements you are taking to ensure your safety and well-being.
Drug disease interaction: The combination of propranolol 40mg (SR) and flunarizine 10mg is often used to treat migraines and certain types of headaches. Both medications are known for their prophylactic (preventive) properties against migraines and can be used in combination to provide better control over migraine attacks.,,Propranolol is a beta-blocker, which means it helps to reduce blood pressure and heart rate. In the context of migraines, it is believed to work by reducing the dilation of blood vessels in the brain and decreasing the release of certain neurotransmitters involved in the migraine process.,,Flunarizine is a calcium channel blocker that also helps in preventing migraines. It works by reducing the influx of calcium into cells, which can lead to a decrease in the excitability of nerve cells in the brain and a reduction in the frequency and severity of migraines.,,Together, propranolol and flunarizine can have a synergistic effect in reducing the frequency and intensity of migraines, making them a valuable combination in the management of this condition.,,As always, it is essential to consult with a healthcare professional before starting or making any changes to medication regimens. They can provide personalized advice and monitor for potential interactions or side effects.
contraindications
The combination of propranolol 40mg (SR - sustained-release) and flunarizine 10mg might have contraindications or precautions, especially if you have certain medical conditions or are taking other medications. Some possible contraindications and precautions for this combination may include:
Hypersensitivity: If you have a known hypersensitivity or allergy to propranolol, flunarizine, or any other ingredients in these medications, their use may be contraindicated.,,Asthma and Respiratory Conditions: Propranolol can cause bronchoconstriction, which may worsen symptoms in individuals with asthma or other respiratory conditions.,,Heart Conditions: Both propranolol and flunarizine can affect heart function. Their combination might be contraindicated in individuals with certain heart conditions, such as heart failure or heart block.,,Low Blood Pressure: Propranolol and flunarizine can lower blood pressure, and their combination may exacerbate this effect, leading to hypotension (low blood pressure).,,Liver or Kidney Impairment: If you have liver or kidney problems, the dosage of these medications may need to be adjusted or they may be contraindicated altogether.,,Migraine with Aura: Flunarizine is not recommended for individuals with a history of migraine with aura, as it may increase the risk of stroke in such cases.,,Depression or Mental Health Disorders: Propranolol has the potential to worsen symptoms in individuals with depression or other mental health disorders.,,Interactions with Other Medications: Propranolol and flunarizine can interact with other medications, including over-the-counter drugs and herbal supplements. Certain combinations may be contraindicated.
other
Follow Your Prescribed Dosage: Take propranolol and flunarizine exactly as prescribed by your doctor. Do not alter the dosage without their approval.,,Take with Food: If the medication label or your doctor recommends taking the pills with food, be sure to do so. This can help reduce the risk of stomach upset.,,Avoid Alcohol: Avoid drinking alcohol while taking these medications, as it may intensify side effects and interactions.,,Inform Your Doctor About All Medications: Make sure your doctor is aware of all the medications, supplements, and herbal products you are taking. Some drugs may interact with propranolol and flunarizine, potentially causing adverse effects.,,Avoid Grapefruit and Grapefruit Juice: Grapefruit and grapefruit juice can interact with certain medications, including flunarizine, affecting their effectiveness or increasing the risk of side effects. Check with your doctor or pharmacist about potential interactions.,,Monitor Blood Pressure: Propranolol is a beta-blocker used to treat high blood pressure and other conditions. Regularly monitor your blood pressure and report any significant changes to your doctor.,,Don't Stop Abruptly: If you need to stop taking propranolol or flunarizine, do not stop suddenly without consulting your doctor. They will guide you on how to taper off the medication safely.,,Driving and Operating Machinery: These medications can cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.,,Allergic Reactions: If you experience any signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.,,Keep in Contact with Your Healthcare Provider: If you experience any new or concerning side effects while taking propranolol and flunarizine, inform your doctor promptly.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Propranolol 40mg (SR) and flunarizine 10mg are two different medications commonly used to manage certain medical conditions. Here's a brief overview of their uses:
Propranolol 40mg (SR): Propranolol is a beta-blocker medication that is primarily used to treat various cardiovascular conditions. Some common uses include:
a. Hypertension (High blood pressure): Propranolol can help lower blood pressure, reducing the strain on the heart and blood vessels.,,b. Angina: It can be prescribed to manage chest pain caused by reduced blood flow to the heart.,,c. Arrhythmias: Propranolol is used to control irregular heart rhythms.,,d. Anxiety and performance anxiety: The medication is sometimes used off-label to manage situational anxiety and performance anxiety, as it can reduce physical symptoms like rapid heartbeat and trembling.,,e. Migraine prophylaxis: Propranolol can be effective in preventing migraines in some individuals.
Flunarizine 10mg:Flunarizine is a calcium channel blocker primarily used for the prophylaxis (prevention) of migraines. It works by reducing the hyperexcitability of nerve cells and dilating blood vessels in the brain, which can help prevent the onset of migraines.
The combination of propranolol and flunarizine may be prescribed by healthcare professionals to manage certain types of migraines and headaches that are not well-controlled by either medication alone. This combination can have a synergistic effect and may provide better relief for some individuals.
As with any medication, it is essential to follow your doctor's advice and take them as prescribed. If you have any questions or concerns about these medications, make sure to discuss them with your healthcare provider.