category
Heart
composition
This drug contain Trimetazidine (mr) 35 mg.
workings
Trimetazidine is a medication used for the treatment of angina pectoris, a condition that causes chest pain due to reduced blood flow to the heart. It works by improving the metabolism of the heart muscle cells, which helps the heart to function more efficiently.
Specifically, trimetazidine works by inhibiting the mitochondrial long-chain 3-ketoacyl coenzyme A thiolase enzyme, which leads to a shift in the metabolism of the heart muscle cells from fatty acid oxidation to glucose oxidation. This shift in metabolism helps the heart muscle cells to generate energy more efficiently and reduces the oxygen demand of the heart, thereby reducing the symptoms of angina.
In summary, Trimetazidine improves the metabolism of the heart muscle cells, reduces the oxygen demand of the heart, and helps to alleviate the symptoms of angina.
usage
Trimetazidine is a medication that is commonly used to treat angina pectoris, a condition where there is chest pain or discomfort due to reduced blood flow to the heart. It works by improving the energy metabolism of the heart muscle, allowing it to function more efficiently and reduce the workload on the heart.
Some of the uses of Trimetazidine (mr) 35 mg include:
Treatment of angina pectoris: Trimetazidine is primarily used to treat stable angina pectoris, which is a type of chest pain that occurs during physical activity or stress.,,Prevention of angina attacks: Trimetazidine (mr) 35 mg can also be used to prevent angina attacks by reducing the frequency and severity of chest pain episodes.,,Heart failure: Trimetazidine has been shown to improve symptoms and exercise tolerance in patients with chronic heart failure.,,Tinnitus: Trimetazidine has been used in some cases to treat tinnitus, a condition where a person experiences ringing or other noises in the ears.,,Vertigo: Trimetazidine has also been used to treat vertigo, a type of dizziness that is often associated with inner ear problems.
It is important to note that Trimetazidine should only be taken under the supervision of a healthcare professional and as directed. It is not recommended for use in patients with severe renal impairment, severe hepatic impairment, or Parkinson's disease.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Headache,,Dizziness,,Nausea,,Vomiting,,Abdominal pain,,Flushing,,Weakness,,Fatigue.
In rare cases, Trimetazidine can cause more serious side effects such as:
Allergic reactions,,Liver damage,,Low blood pressure,,Abnormal heart rhythms.
warnings
Warning: Trimetazidine is a medication used for the treatment of angina pectoris (chest pain). It works by improving blood flow to the heart and reducing the workload on the heart muscle.
Like all medications, Trimetazidine has potential side effects, and it's important to be aware of them. Some common side effects of Trimetazidine include:
Headache,,Dizziness,,Nausea,,Vomiting,,Abdominal pain,,Flushing,,Weakness,,Fatigue.
In rare cases, Trimetazidine can cause more serious side effects such as:
Allergic reactions,,Liver damage,,Low blood pressure,,Abnormal heart rhythms.
It's important to let your doctor know if you experience any unusual symptoms while taking Trimetazidine. They can advise you on whether to continue taking the medication or adjust your dosage.
Additionally, Trimetazidine should not be used in patients with severe kidney or liver disease, and caution should be used in patients with moderate kidney or liver disease.
As with any medication, it's important to take Trimetazidine (mr) 35 mg exactly as prescribed by your doctor and not to exceed the recommended dosage. If you have any concerns or questions about taking Trimetazidine, be sure to talk to your doctor.
interactions
Drug drug interaction: Trimetazidine (mr) 35 mg is a medication used to treat angina, a type of chest pain that occurs due to reduced blood flow to the heart. It works by improving the use of oxygen by the heart muscle.
There are several drugs that can interact with Trimetazidine. Some of the most common interactions include:
CYP2D6 inhibitors: Trimetazidine is metabolized by the liver enzyme CYP2D6. Drugs that inhibit this enzyme can increase the levels of Trimetazidine in the body, potentially leading to adverse effects. Some examples of CYP2D6 inhibitors include fluoxetine, paroxetine, and quinidine.
Beta-blockers: Trimetazidine can enhance the effects of beta-blockers, which are medications used to treat high blood pressure and other heart conditions. This can lead to a significant decrease in heart rate and blood pressure, which can be dangerous in some cases.
Calcium channel blockers: Similar to beta-blockers, calcium channel blockers are also used to treat heart conditions. They can also enhance the effects of Trimetazidine, leading to a decrease in blood pressure.
Nitrates: Nitrates are medications that are used to treat angina by relaxing the blood vessels and increasing blood flow to the heart. When combined with Trimetazidine, the effects of nitrates can be enhanced, leading to a significant drop in blood pressure.,,It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements, to avoid any potential interactions with Trimetazidine.
Drug food interaction:Trimetazidine (mr) 35 mg is a medication used to treat angina pectoris, a type of chest pain caused by insufficient blood flow to the heart.
There is no known interaction between Trimetazidine and specific foods. However, it's always advisable to take the medication with a glass of water or after a meal to reduce the risk of stomach upset.
It's important to follow the instructions of your healthcare provider regarding the timing and dosage of Trimetazidine. If you have any concerns or questions about taking this medication, it's best to consult with your doctor or pharmacist for personalized advice.
Drug disease interaction: Trimetazidine (mr) 35 mg is a medication used to treat angina pectoris (chest pain) associated with coronary artery disease. It works by improving the metabolic efficiency of the heart muscle and reducing the oxygen requirement of the heart.
Trimetazidine is not indicated for the treatment of any other disease, and should only be used as directed by a healthcare professional. It is important to talk to your doctor about any medications you are taking and any medical conditions you may have before starting Trimetazidine or any other medication.
contraindications
Trimetazidine (mr) 35 mg is a medication used for the treatment of angina pectoris and certain other heart conditions. As with any medication, there are certain contraindications or situations where it should not be used or used with caution.
The contraindications for Trimetazidine (mr) 35 mg include:
Hypersensitivity to the active ingredient or any of the other ingredients in the medication,,Severe renal impairment (creatinine clearance less than 30 ml/min),,Parkinson's disease or other related movement disorders,,Pregnancy and breastfeeding,,Children under 18 years of age.
Trimetazidine should also be used with caution in patients with moderate renal impairment (creatinine clearance between 30-60 ml/min) and those with liver impairment. Additionally, it should not be used in combination with drugs that prolong the QT interval, such as certain antibiotics and antifungal medications, or with drugs that inhibit CYP2D6, such as certain antidepressants and antipsychotics.
It is important to consult with a healthcare provider before starting Trimetazidine or any other medication to ensure that it is safe and appropriate for you.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Trimetazidine is a medication that is commonly used to treat angina pectoris, a condition where there is chest pain or discomfort due to reduced blood flow to the heart. It works by improving the energy metabolism of the heart muscle, allowing it to function more efficiently and reduce the workload on the heart.
Some of the uses of Trimetazidine (mr) 35 mg include:
Treatment of angina pectoris: Trimetazidine is primarily used to treat stable angina pectoris, which is a type of chest pain that occurs during physical activity or stress.,,Prevention of angina attacks: Trimetazidine (mr) 35 mg can also be used to prevent angina attacks by reducing the frequency and severity of chest pain episodes.,,Heart failure: Trimetazidine has been shown to improve symptoms and exercise tolerance in patients with chronic heart failure.,,Tinnitus: Trimetazidine has been used in some cases to treat tinnitus, a condition where a person experiences ringing or other noises in the ears.,,Vertigo: Trimetazidine has also been used to treat vertigo, a type of dizziness that is often associated with inner ear problems.
It is important to note that Trimetazidine should only be taken under the supervision of a healthcare professional and as directed. It is not recommended for use in patients with severe renal impairment, severe hepatic impairment, or Parkinson's disease.