Heart

This drug contain Ramipril 5 mg + hydrochlorothiazide 12.5 mg

Ramipril 5mg is an angiotensin-converting enzyme (ACE) inhibitor that helps to relax blood vessels, decrease blood pressure, and reduce the workload on the heart. It works by blocking the action of ACE, which is an enzyme that converts angiotensin I to angiotensin II, a hormone that constricts blood vessels and increases blood pressure. By blocking the action of ACE, ramipril reduces the production of angiotensin II, resulting in vasodilation and lower blood pressure.

Hydrochlorothiazide 12.5mg is a thiazide diuretic that helps to eliminate excess fluid and salt from the body. It works by inhibiting the reabsorption of sodium and chloride ions in the kidneys, leading to increased urine output and reduced fluid volume in the body. This reduces the workload on the heart and blood vessels, leading to lower blood pressure.

When used in combination, ramipril and hydrochlorothiazide work synergistically to lower blood pressure by reducing the resistance in blood vessels and decreasing the fluid volume in the body. The combination therapy is used to treat hypertension (high blood pressure) and reduce the risk of cardiovascular events such as heart attack and stroke.

Ramipril 5mg + hydrochlorothiazide 12.5mg is a combination medication used to treat high blood pressure (hypertension). Ramipril belongs to a class of drugs called ACE inhibitors, which helps to relax blood vessels and reduce the workload on the heart. Hydrochlorothiazide is a diuretic that helps to remove excess water and salt from the body, which also helps to lower blood pressure.

Here are some uses of Ramipril 5mg + hydrochlorothiazide 12.5mg:

High blood pressure: This combination medication is primarily used to treat hypertension or high blood pressure, which can lead to serious health problems such as heart disease, stroke, and kidney failure.,,Heart failure: This medication can also be used to treat heart failure, which occurs when the heart is unable to pump blood effectively to meet the body's needs.,,Post-heart attack treatment: Ramipril and hydrochlorothiazide can also be used to help prevent further heart attacks in patients who have recently had a heart attack.

It's important to note that Ramipril 5mg + hydrochlorothiazide 12.5mg should only be used under the supervision of a healthcare professional and as prescribed. Additionally, this medication may cause side effects, so it's important to talk to your doctor if you experience any symptoms or have concerns about taking this medication.

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

Dizziness,,Headache,,Fatigue or weakness,,Nausea or vomiting,,Dry cough,,Diarrhea,,Muscle cramps,,Increased sensitivity to sunlight,,Skin rash or itching,,Erectile dysfunction,,Fainting or lightheadedness,,Difficulty breathing,,Swelling of the face, lips, tongue, or throat,,Rapid or irregular heartbeat,,Signs of an allergic reaction, such as hives, itching, or difficulty breathing.

Warning: Ramipril 5 mg and hydrochlorothiazide 12.5 mg are medications commonly used to treat high blood pressure. However, like all medications, they can have potential side effects and warnings that should be taken into consideration.

Some of the warnings associated with Ramipril 5 mg + hydrochlorothiazide 12.5 mg include:

Hypotension: This medication combination can lower blood pressure to a point where it may cause dizziness, fainting or even shock, especially if the patient has low blood volume or is taking other medications that lower blood pressure.

Electrolyte imbalances: Hydrochlorothiazide is a diuretic that can lead to electrolyte imbalances, such as low potassium or sodium levels, which may cause muscle weakness, cramps, or irregular heartbeats.

Kidney function impairment: Both Ramipril and hydrochlorothiazide can affect kidney function, particularly in patients with pre-existing kidney disease or those taking other medications that can damage the kidneys.

Liver function impairment: Ramipril can also affect liver function, particularly in patients with pre-existing liver disease.

Allergic reactions: Both Ramipril and hydrochlorothiazide can cause allergic reactions in some patients, which may manifest as skin rashes, swelling, difficulty breathing, or anaphylactic shock.

It is important to note that these are not the only potential side effects or warnings associated with Ramipril 5 mg + hydrochlorothiazide 12.5 mg. Patients should always consult their healthcare provider before starting or stopping any medication, and should promptly report any adverse reactions or symptoms to their healthcare provider.

Drug drug interaction: There are several drugs that may interact with Ramipril 5 mg + Hydrochlorothiazide 12.5 mg. These include:

Other Blood Pressure Medications: Combining Ramipril and Hydrochlorothiazide with other blood pressure medications may result in a dangerous drop in blood pressure.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs like ibuprofen, naproxen, and aspirin may reduce the effectiveness of Ramipril and Hydrochlorothiazide.

Lithium: The combination of lithium and Ramipril and Hydrochlorothiazide may increase the risk of lithium toxicity.

Potassium-sparing diuretics: Combining Ramipril and Hydrochlorothiazide with potassium-sparing diuretics such as spironolactone, triamterene or amiloride may result in high potassium levels which can be dangerous.

Diabetes medications: Ramipril and Hydrochlorothiazide may increase the blood sugar-lowering effects of diabetes medications, such as insulin or oral hypoglycemics, increasing the risk of hypoglycemia.

It is important to inform your doctor of all medications, supplements, and herbal products you are taking before starting Ramipril and Hydrochlorothiazide to prevent any possible interactions.

Drug food interactions: Ramipril and hydrochlorothiazide are medications used to treat high blood pressure. While there are no specific dietary restrictions associated with the use of these medications, it is generally recommended that you avoid excessive consumption of salt, as this can counteract the blood pressure-lowering effects of the medication.

Additionally, it is important to discuss any changes to your diet with your healthcare provider, as certain foods or dietary supplements may interact with your medication or affect your blood pressure. For example, grapefruit juice can interact with many medications, including ramipril, and may increase the risk of side effects or reduce the effectiveness of the medication.

It's always a good idea to talk to your doctor or pharmacist about any concerns you have about medication interactions or dietary restrictions.

Drug disease interaction: Ramipril 5 mg + hydrochlorothiazide 12.5 mg is a combination medication used to treat high blood pressure. This medication is not recommended for use in certain conditions, such as:

Allergy: If a person is allergic to any of the ingredients in Ramipril 5 mg + hydrochlorothiazide 12.5 mg, then they should not take this medication.,,Angioedema: Ramipril 5 mg + hydrochlorothiazide 12.5 mg should not be used in patients with a history of angioedema, a condition that causes rapid swelling of the skin and mucous membranes.,,Severe kidney disease: Ramipril 5 mg + hydrochlorothiazide 12.5 mg should not be used in patients with severe kidney disease as it can worsen kidney function.,,Liver disease: Patients with liver disease should be cautious when taking Ramipril 5 mg + hydrochlorothiazide 12.5 mg as it can cause liver problems.,,Pregnancy: Ramipril 5 mg + hydrochlorothiazide 12.5 mg should not be used during pregnancy as it can harm the developing fetus.

It is important to consult with a healthcare provider before taking Ramipril 5 mg + hydrochlorothiazide 12.5 mg, as they can determine whether this medication is appropriate for an individual's specific medical condition.

Ramipril and hydrochlorothiazide combination is used to treat hypertension (high blood pressure). While this medication is generally safe and effective, there are certain conditions where it may not be appropriate. Some of the contraindications of Ramipril 5 mg + hydrochlorothiazide 12.5 mg include:

Hypersensitivity: Patients with a known hypersensitivity to any of the ingredients in this medication should not use it.,,Anuria: Patients with anuria (absence of urine production) should not use Ramipril and hydrochlorothiazide.,,Pregnancy: Ramipril and hydrochlorothiazide combination is contraindicated during pregnancy due to the risk of fetal harm.,,Severe hepatic impairment: This medication is not recommended in patients with severe liver disease.,,Severe renal impairment: Ramipril and hydrochlorothiazide combination is contraindicated in patients with severe renal impairment (creatinine clearance less than 30 mL/min).,,Hyperkalemia: This medication should not be used in patients with high potassium levels in the blood (hyperkalemia).,,Concomitant use of aliskiren: Ramipril and hydrochlorothiazide combination is contraindicated in patients who are taking aliskiren-containing products, as this combination may increase the risk of renal impairment, hypotension, and hyperkalemia.

It is important to always consult with a healthcare professional before taking any medication to determine if it is safe and appropriate for you.

Store this medicine at room temperature, away from sunlight and moisture.

Ramipril 5mg + hydrochlorothiazide 12.5mg is a combination medication used to treat high blood pressure (hypertension). Ramipril belongs to a class of drugs called ACE inhibitors, which helps to relax blood vessels and reduce the workload on the heart. Hydrochlorothiazide is a diuretic that helps to remove excess water and salt from the body, which also helps to lower blood pressure.

Here are some uses of Ramipril 5mg + hydrochlorothiazide 12.5mg:

High blood pressure: This combination medication is primarily used to treat hypertension or high blood pressure, which can lead to serious health problems such as heart disease, stroke, and kidney failure.,,Heart failure: This medication can also be used to treat heart failure, which occurs when the heart is unable to pump blood effectively to meet the body's needs.,,Post-heart attack treatment: Ramipril and hydrochlorothiazide can also be used to help prevent further heart attacks in patients who have recently had a heart attack.

It's important to note that Ramipril 5mg + hydrochlorothiazide 12.5mg should only be used under the supervision of a healthcare professional and as prescribed. Additionally, this medication may cause side effects, so it's important to talk to your doctor if you experience any symptoms or have concerns about taking this medication.