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lumether forte tablet dt

artemether 80 mg + lumefantrine 480 mg

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Antibiotic

composition

This drug contain Artemether 80 mg + lumefantrine 480 mg

workings

Artemether 80 mg + lumefantrine 480 mg is a combination medication used to treat malaria.

Artemether is a fast-acting antimalarial drug that belongs to the artemisinin class of drugs. It works by killing the malaria parasites during their asexual reproduction cycle in the red blood cells. Artemether rapidly reduces the number of parasites in the blood and provides quick relief from malaria symptoms.

Lumefantrine, on the other hand, is a longer-acting antimalarial drug that belongs to the aryl amino alcohol class of drugs. It works by preventing the growth and reproduction of malaria parasites in the body, which helps to prevent the recurrence of the infection.

When combined, artemether and lumefantrine work together synergistically to treat malaria effectively. The fast-acting artemether quickly reduces the number of parasites in the blood, while the longer-acting lumefantrine continues to suppress the growth and reproduction of the remaining parasites in the body, thereby preventing recurrence of the infection. This combination medication is recommended for the treatment of uncomplicated malaria caused by Plasmodium falciparum, which is the most deadly form of malaria.

usage

Artemether 80 mg + Lumefantrine 480 mg is a combination medication used to treat malaria caused by Plasmodium falciparum and Plasmodium vivax. This medication is available in tablet form and is commonly sold under the brand name Coartem or Riamet.,,Malaria is a serious and potentially life-threatening disease caused by a parasite that is transmitted to humans through the bites of infected mosquitoes. Artemether and Lumefantrine work together to kill the malaria parasite in the blood.,,Here are some uses of Artemether 80 mg + Lumefantrine 480 mg:

Treatment of uncomplicated malaria: Artemether-Lumefantrine is used to treat uncomplicated malaria caused by Plasmodium falciparum or Plasmodium vivax.,,Prevention of malaria: Artemether-Lumefantrine is not typically used for prevention of malaria, but it may be used in certain situations, such as when traveling to areas with a high risk of malaria transmission.,,Treatment of severe malaria: Artemether-Lumefantrine is not recommended for the treatment of severe malaria, which is a medical emergency that requires hospitalization.,,Treatment of mixed infections: Artemether-Lumefantrine may be used to treat mixed infections, which occur when more than one type of malaria parasite is present.

It is important to note that Artemether-Lumefantrine should be taken exactly as prescribed by a healthcare professional, and patients should complete the full course of treatment to ensure that the malaria infection is fully cleared from the body. Additionally, this medication may cause side effects, such as nausea, vomiting, headache, and dizziness, and patients should discuss any concerns or questions with their healthcare provider.

directions

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

side effects

Artemether and lumefantrine are medications commonly used to treat malaria. When taken as prescribed, these medications are generally safe and well-tolerated. However, like all medications, they can have side effects. Some common side effects of artemether/lumefantrine include:

Nausea,,Vomiting,,Headache,,Dizziness,,Loss of appetite,,Stomach pain,,Diarrhea,,Fatigue,,Muscle pain,,Insomnia.

Less common side effects include:

Allergic reactions (rash, itching, swelling of the face/tongue/throat),,Changes in heart rhythm,,Low blood pressure,,Liver problems,,Hearing problems,,Visual disturbances,,Psychiatric symptoms (anxiety, confusion, hallucinations).

If you experience any of these side effects while taking artemether/lumefantrine, it's important to contact your healthcare provider right away. Additionally, if you experience any new or unusual symptoms, it's important to inform your healthcare provider as well.

warnings

Warning: Artemether 80 mg + lumefantrine 480 mg is a combination medication used to treat uncomplicated malaria caused by Plasmodium falciparum. However, like all medications, it can have potential side effects and risks. Some of the warnings associated with this medication include:

Allergic reactions: Patients who are allergic to artemether or lumefantrine or any of the ingredients in the medication should not take it. Allergic reactions can range from mild skin rashes to severe anaphylaxis, which can be life-threatening.,,Cardiac effects: This medication can affect the heart's electrical activity, leading to changes in heart rhythm (QT prolongation). Patients with a history of heart problems, such as arrhythmia, should be closely monitored when taking this medication.,,Liver function: Artemether and lumefantrine can cause liver problems, especially in patients with pre-existing liver disease. Regular liver function tests should be performed to monitor liver function.,,Pregnancy and breastfeeding: This medication should be used with caution in pregnant and breastfeeding women. It is recommended to consult with a healthcare provider before taking this medication.,,Drug interactions: This medication can interact with other medications, including those used to treat HIV, tuberculosis, and certain antibiotics. Patients should inform their healthcare provider about all medications they are taking before starting this medication.

It is important to follow the prescribed dosing and frequency of this medication to minimize the risk of adverse effects. Patients should also report any unusual symptoms or side effects to their healthcare provider promptly.

interactions

Drug drug interaction: Artemether-lumefantrine is a combination medication used to treat malaria. There are several drugs that can interact with artemether-lumefantrine and affect its effectiveness or cause side effects.Some of the drugs that may interact with artemether-lumefantrine include:

Drugs that prolong the QT interval: Artemether-lumefantrine can also prolong the QT interval, which is a measure of heart rhythm. Other drugs that prolong the QT interval, such as some antibiotics, antifungal medications, and antidepressants, can increase the risk of a potentially life-threatening heart rhythm disorder called torsades de pointes.,,Drugs that induce or inhibit CYP3A4 enzymes: Artemether-lumefantrine is primarily metabolized by the CYP3A4 enzyme system. Drugs that induce or inhibit this enzyme can affect the metabolism of artemether-lumefantrine and alter its effectiveness or toxicity. Examples of such drugs include rifampin, ketoconazole, and ritonavir.,,Antacids and other drugs that reduce stomach acid: Artemether-lumefantrine may not be absorbed properly when taken with drugs that reduce stomach acid, such as antacids, proton pump inhibitors, or H2 blockers. This can reduce its effectiveness.,,Drugs that lower the seizure threshold: Artemether-lumefantrine can lower the seizure threshold, which is the level of stimulation required to trigger a seizure. Other drugs that lower the seizure threshold, such as certain antidepressants, antipsychotics, and antihistamines, can increase the risk of seizures.

It's important to talk to your doctor or pharmacist about all the medications, supplements, and herbal products you're taking before starting artemether-lumefantrine. They can help you avoid potentially harmful drug interactions.

Drug food interaction: Artemether-lumefantrine is a medication used to treat malaria. When taking this medication, it is important to avoid certain foods and drinks that may interact with it and reduce its effectiveness. Here are some dietary considerations to keep in mind while taking artemether 80 mg + lumefantrine 480 mg:

Grapefruit juice: Grapefruit juice can interfere with the metabolism of artemether-lumefantrine and increase its concentration in the bloodstream, leading to potential side effects. Therefore, it is best to avoid grapefruit juice while taking this medication.,,High-fat meals: High-fat meals can also interfere with the absorption of artemether-lumefantrine, and it is recommended to take the medication with a light meal or snack to maximize its effectiveness.,,Alcohol: Drinking alcohol can increase the risk of certain side effects of artemether-lumefantrine, such as dizziness and drowsiness. Therefore, it is best to avoid alcohol while taking this medication.

It is important to talk to your healthcare provider about any potential food or drug interactions before taking artemether-lumefantrine or any other medication.

Drug disease interaction: Artemether 80 mg + lumefantrine 480 mg is a combination medication used for the treatment of uncomplicated malaria caused by Plasmodium falciparum and Plasmodium vivax. It is commonly sold under the brand name Coartem.

This medication is specifically indicated for the treatment of malaria, and it is not used to treat any other diseases. It works by killing the malaria parasites that have entered the patient's bloodstream.

It is important to note that this medication should only be used under the guidance and supervision of a healthcare professional. Additionally, patients should not self-diagnose and self-treat themselves with this medication. If you suspect that you have malaria, please consult a doctor for proper diagnosis and treatment.

contraindications

Artemether 80 mg + Lumefantrine 480 mg is a combination drug used for the treatment of malaria.,,There are some contraindications for this medication.,,Hypersensitivity: The drug is contraindicated in patients with a known hypersensitivity to any of its ingredients.,,Cardiac Conduction Abnormalities: Artemether and Lumefantrine may prolong the QT interval in the heart, which could lead to serious cardiac arrhythmias. Therefore, it is contraindicated in patients with a history of cardiac conduction abnormalities or taking medications that may prolong the QT interval.,,Hepatic Impairment: Artemether and Lumefantrine are metabolized in the liver, and the drug concentrations may increase in patients with hepatic impairment. Hence, this medication is contraindicated in patients with severe hepatic impairment.,,Pregnancy and Breastfeeding: Artemether and Lumefantrine have not been studied adequately in pregnant and breastfeeding women. Hence, it is contraindicated in pregnant women during the first trimester and in breastfeeding women.

It is important to consult a healthcare provider before taking any medication to ensure that it is safe and appropriate for your individual situation.

storage

Store this medicine at room temperature, away from sunlight and moisture.

directions use

Artemether 80 mg + Lumefantrine 480 mg is a combination medication used to treat malaria caused by Plasmodium falciparum and Plasmodium vivax. This medication is available in tablet form and is commonly sold under the brand name Coartem or Riamet.,,Malaria is a serious and potentially life-threatening disease caused by a parasite that is transmitted to humans through the bites of infected mosquitoes. Artemether and Lumefantrine work together to kill the malaria parasite in the blood.,,Here are some uses of Artemether 80 mg + Lumefantrine 480 mg:

Treatment of uncomplicated malaria: Artemether-Lumefantrine is used to treat uncomplicated malaria caused by Plasmodium falciparum or Plasmodium vivax.,,Prevention of malaria: Artemether-Lumefantrine is not typically used for prevention of malaria, but it may be used in certain situations, such as when traveling to areas with a high risk of malaria transmission.,,Treatment of severe malaria: Artemether-Lumefantrine is not recommended for the treatment of severe malaria, which is a medical emergency that requires hospitalization.,,Treatment of mixed infections: Artemether-Lumefantrine may be used to treat mixed infections, which occur when more than one type of malaria parasite is present.

It is important to note that Artemether-Lumefantrine should be taken exactly as prescribed by a healthcare professional, and patients should complete the full course of treatment to ensure that the malaria infection is fully cleared from the body. Additionally, this medication may cause side effects, such as nausea, vomiting, headache, and dizziness, and patients should discuss any concerns or questions with their healthcare provider.

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