category
Heart
composition
This drug contain Losartan 50 mg + amlodipine 5 mg
workings
Losartan and amlodipine are both medications used to treat hypertension (high blood pressure). They work in different ways to help lower blood pressure.
Losartan is an angiotensin receptor blocker (ARB), which means it blocks the action of a hormone called angiotensin II. Angiotensin II is a powerful vasoconstrictor, which means it causes blood vessels to narrow, increasing blood pressure. By blocking the action of angiotensin II, losartan causes blood vessels to relax and widen, which helps to lower blood pressure.
Amlodipine is a calcium channel blocker (CCB), which means it works by blocking the entry of calcium into the smooth muscle cells of blood vessels. Calcium is needed for the muscles to contract, so by blocking calcium, amlodipine causes blood vessels to relax and widen, which also helps to lower blood pressure.
When losartan and amlodipine are used together, they have a complementary effect on blood pressure reduction. Losartan targets the renin-angiotensin system, while amlodipine targets the calcium channels, resulting in a greater reduction in blood pressure than when either medication is used alone. The combination of losartan and amlodipine can help to lower blood pressure and improve cardiovascular outcomes for patients with hypertension.
usage
Losartan 50 mg + amlodipine 5 mg is a combination medication used to treat hypertension (high blood pressure). Losartan is an angiotensin receptor blocker (ARB) that helps to relax blood vessels and reduce blood pressure, while amlodipine is a calcium channel blocker (CCB) that also helps to relax blood vessels and improve blood flow.,,Some of the uses of Losartan 50 mg + amlodipine 5 mg include:
Hypertension: This medication is primarily used to treat high blood pressure in adults. It can help to lower blood pressure and reduce the risk of heart attack, stroke, and other complications associated with hypertension.,,Chronic Kidney Disease: Losartan 50 mg + amlodipine 5 mg may also be prescribed to people with chronic kidney disease to help protect their kidneys and reduce the risk of complications.,,Heart failure: This medication can also be used to treat heart failure, a condition where the heart is not able to pump enough blood to meet the body's needs.,,Coronary artery disease: Losartan 50 mg + amlodipine 5 mg can be used to treat coronary artery disease, a condition where the blood vessels that supply blood to the heart become narrow or blocked.
It is important to note that Losartan 50 mg + amlodipine 5 mg should only be used under the supervision of a healthcare provider, as it can interact with other medications and may not be suitable for everyone.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Dizziness,,Fatigue,,Headache,,Nausea,,Flushing,,Swelling in the ankles or feet,,Abdominal pain,,Diarrhea.
More serious side effects are rare but can occur, and may include:
Severe allergic reactions (difficulty breathing, swelling of the face, lips, tongue or throat),,Low blood pressure,,Slow heart rate,,Irregular heartbeat,,Liver problems,,Kidney problems,,Muscle pain or weakness.
warnings
Warning: Losartan and amlodipine are commonly prescribed medications used to treat high blood pressure. However, it is important to note that all medications have potential side effects and risks.,,Possible side effects of Losartan include dizziness, tiredness, nausea, and stomach pain. Rare but serious side effects include allergic reactions, kidney problems, and liver problems.,,Similarly, Amlodipine can cause side effects such as dizziness, flushing, headache, and swollen ankles. In rare cases, it can also cause more serious side effects such as irregular heartbeat, chest pain, and swelling of the hands, ankles, or feet.,,Combining Losartan and Amlodipine can increase the risk of certain side effects such as low blood pressure, dizziness, and fatigue. However, this combination is often used to effectively manage high blood pressure in some patients.,,It is important to follow your doctor's instructions when taking any medication and to report any side effects or concerns to your healthcare provider.
interactions
Drug drug interaction: There are many drugs that can interact with Losartan 50 mg + Amlodipine 5 mg, so it's important to always consult with a healthcare professional before starting any new medications or supplements. Some common drugs that may interact with Losartan and Amlodipine include:
Other blood pressure medications - using multiple blood pressure medications can increase the risk of low blood pressure or other adverse effects.,,Diuretics (water pills) - these medications can also lower blood pressure and increase the risk of low blood pressure.,,Nonsteroidal anti-inflammatory drugs (NSAIDs) - taking NSAIDs such as ibuprofen or naproxen with Losartan and Amlodipine can reduce the effectiveness of the blood pressure medication and increase the risk of kidney damage.,,Antifungal medications - some antifungal medications can increase the levels of Losartan and Amlodipine in the body, which can increase the risk of adverse effects.,,Grapefruit juice - drinking grapefruit juice can increase the levels of Amlodipine in the body, which can increase the risk of adverse effects.
Again, it's important to speak with your healthcare professional about any medications or supplements you are taking, as well as any potential interactions that may occur.
Drug food interaction: Losartan 50 mg and Amlodipine 5 mg are medications used to treat high blood pressure. There are certain foods that may interact with these medications and affect their effectiveness or cause side effects.,,Grapefruit: Grapefruit and grapefruit juice can increase the concentration of Amlodipine in the blood, which can lead to increased side effects such as low blood pressure and dizziness.,,High-sodium foods: Foods high in sodium can decrease the effectiveness of Losartan and Amlodipine in lowering blood pressure. It is recommended to limit sodium intake to no more than 2,300 mg per day.,,Potassium-rich foods: Foods high in potassium, such as bananas, spinach, avocados, and potatoes, can increase the levels of potassium in the blood. While this is generally a good thing, too much potassium can be dangerous, especially for people with kidney problems. It is recommended to consult with a doctor or a registered dietitian for personalized recommendations.,,Alcohol: Drinking alcohol while taking Losartan and Amlodipine can increase the risk of dizziness, lightheadedness, and fainting. It is recommended to limit alcohol intake or avoid it altogether.,,Caffeine: Caffeine can increase blood pressure temporarily and may interfere with the blood pressure-lowering effects of Losartan and Amlodipine. It is recommended to limit caffeine intake, especially if you experience high blood pressure.,,It is important to talk to a doctor or a registered dietitian if you have any concerns or questions about how to incorporate these foods into your diet while taking Losartan and Amlodipine.
Drug disease interaction: Losartan 50 mg + amlodipine 5 mg is a combination medication that is commonly used to treat high blood pressure. It is not a specific treatment for any particular disease, but it can help manage and control high blood pressure in people with various underlying health conditions, including:
Hypertension (high blood pressure),,Coronary artery disease (narrowing of the blood vessels that supply the heart),,Heart failure (when the heart is not pumping efficiently),,Chronic kidney disease (damage to the kidneys that impairs their function).
If you have a specific medical condition, it is important to speak with your doctor about whether Losartan 50 mg + amlodipine 5 mg is an appropriate treatment option for you, as there may be other medications or treatment approaches that are more suitable for your individual needs.
contraindications
Losartan 50 mg + amlodipine 5 mg is a combination medication that is used to treat hypertension (high blood pressure).,,There are several contraindications to this medication, which means that certain people should not take it or should use it with caution. Some of the contraindications include:
Hypersensitivity: People who are allergic to losartan or amlodipine should not take this medication.,,Pregnancy and breastfeeding: This medication can harm a developing fetus and may pass into breast milk, so it should not be used during pregnancy or while breastfeeding.,,Liver or kidney disease: This medication is processed by the liver and kidneys, so people with liver or kidney disease may not be able to clear the medication from their system as well and may need a lower dose.,,Severe hypotension: This medication can lower blood pressure, so people with severe hypotension (low blood pressure) should not take it.,,Children: The safety and efficacy of this medication have not been established in children, so it should not be used in children under the age of 18.
It's important to note that this is not a complete list of contraindications, and you should always consult with a healthcare professional before starting any new medication.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Losartan 50 mg + amlodipine 5 mg is a combination medication used to treat hypertension (high blood pressure). Losartan is an angiotensin receptor blocker (ARB) that helps to relax blood vessels and reduce blood pressure, while amlodipine is a calcium channel blocker (CCB) that also helps to relax blood vessels and improve blood flow.,,Some of the uses of Losartan 50 mg + amlodipine 5 mg include:
Hypertension: This medication is primarily used to treat high blood pressure in adults. It can help to lower blood pressure and reduce the risk of heart attack, stroke, and other complications associated with hypertension.,,Chronic Kidney Disease: Losartan 50 mg + amlodipine 5 mg may also be prescribed to people with chronic kidney disease to help protect their kidneys and reduce the risk of complications.,,Heart failure: This medication can also be used to treat heart failure, a condition where the heart is not able to pump enough blood to meet the body's needs.,,Coronary artery disease: Losartan 50 mg + amlodipine 5 mg can be used to treat coronary artery disease, a condition where the blood vessels that supply blood to the heart become narrow or blocked.
It is important to note that Losartan 50 mg + amlodipine 5 mg should only be used under the supervision of a healthcare provider, as it can interact with other medications and may not be suitable for everyone.