Diabetes

This drug contain Gliclazide (mr) 60mg + metformin (er) 500 mg.

Gliclazide (MR) and metformin (ER) are two medications commonly used in the treatment of type 2 diabetes. Let's understand how each of these medications works and how their combination can be beneficial in managing diabetes.,,Gliclazide (MR) 60mg: Gliclazide is a type of oral antidiabetic medication known as a sulfonylurea. It works by stimulating the beta cells in the pancreas to produce and release more insulin. Insulin is a hormone that helps regulate blood sugar levels by facilitating the uptake of glucose into cells, where it can be used for energy or stored for future use.

By increasing insulin secretion, gliclazide helps lower elevated blood sugar levels, especially after meals when blood glucose tends to rise due to food intake. It is important to note that gliclazide is effective when there is still some functioning of the pancreas' beta cells. It may not be as effective in individuals with significantly impaired beta cell function.

Metformin (ER) 500 mg:Metformin belongs to the class of drugs called biguanides and is considered a first-line treatment for type 2 diabetes. It works primarily by reducing the amount of glucose produced by the liver. In people with type 2 diabetes, the liver sometimes overproduces glucose, leading to elevated blood sugar levels even when a person is not eating.,,Metformin also helps improve the sensitivity of cells to insulin, making it easier for cells to take up glucose from the bloodstream. This action reduces insulin resistance, a hallmark feature of type 2 diabetes, and helps improve overall blood sugar control.

Combination Therapy:The combination of gliclazide (MR) and metformin (ER) is often prescribed when a single medication is not sufficient to achieve adequate blood sugar control. The combination of these two medications can complement each other's actions and offer better glycemic control compared to using either medication alone.,,The combination helps address different aspects of diabetes pathophysiology. Gliclazide stimulates insulin secretion, primarily targeting the post-meal increase in blood glucose levels. On the other hand, metformin addresses insulin resistance and reduces excessive glucose production by the liver, targeting fasting and overall blood glucose levels.

It is essential to take these medications as prescribed and follow the guidance of a healthcare professional to monitor blood sugar levels regularly and adjust the dosage if needed. Diabetes management is typically multifaceted and includes lifestyle changes like diet and exercise in addition to medication to achieve optimal outcomes.

Gliclazide (MR) and metformin (ER) are two medications commonly used to treat type 2 diabetes mellitus. Let's explore the uses and benefits of each medication.,,Gliclazide (MR) 60mg: Gliclazide is an oral antidiabetic medication that belongs to the class of sulfonylureas. It works by stimulating the pancreas to release insulin, which helps lower blood sugar levels. Here are its primary uses:Type 2 diabetes mellitus: Gliclazide is mainly prescribed for people with type 2 diabetes who have not achieved adequate blood sugar control through diet and exercise alone. It is typically used when lifestyle modifications and metformin are insufficient to control blood glucose levels.

Metformin (ER) 500mg:Metformin is an oral biguanide medication and is considered a first-line treatment for type 2 diabetes. It works by reducing the production of glucose by the liver and increasing the body's sensitivity to insulin. Here are its primary uses:Type 2 diabetes mellitus: Metformin is commonly prescribed as a first-line treatment for type 2 diabetes, especially for individuals who are overweight or obese. It helps improve insulin sensitivity and decreases glucose production by the liver, leading to better blood sugar control.,,Polycystic ovary syndrome (PCOS): Metformin is also used to manage hormonal imbalances and insulin resistance associated with polycystic ovary syndrome in women.,,Gestational diabetes: In some cases, metformin may be prescribed for women with gestational diabetes when diet and exercise alone are not sufficient to control blood sugar levels during pregnancy.

Combination therapy:The combination of Gliclazide (MR) 60mg and Metformin (ER) 500mg may be prescribed in cases where a single medication is not providing adequate glycemic control. Combining medications with different mechanisms of action can have a synergistic effect, leading to better blood sugar management. It's essential to follow your doctor's prescription and recommendations while taking these medications and to monitor blood sugar levels regularly.

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

Side effects of Gliclazide (MR) 60mg:Hypoglycemia: Gliclazide can lower blood sugar levels, and if it drops too much, it can lead to symptoms of hypoglycemia, including shakiness, dizziness, sweating, confusion, and fainting.,,Weight gain: Some people may experience weight gain while taking Gliclazide.,,Gastrointestinal disturbances: This may include nausea, vomiting, diarrhea, or stomach upset.,,Skin reactions: In rare cases, Gliclazide may cause skin rashes or other allergic reactions.,,Side effects of Metformin (ER) 500mg:,,Gastrointestinal issues: Metformin can cause gastrointestinal side effects, especially when starting the medication or increasing the dose. This may include nausea, diarrhea, abdominal discomfort, or loss of appetite.,,Vitamin B12 deficiency: Long-term use of Metformin may lead to reduced absorption of vitamin B12, which can result in anemia or nerve-related symptoms.,,Lactic acidosis (rare): Although very rare, Metformin can potentially lead to a serious condition called lactic acidosis, particularly in individuals with impaired kidney function or other medical conditions.

It's important to note that not everyone will experience these side effects, and many people tolerate Gliclazide and Metformin well. If you are prescribed these medications and notice any concerning symptoms or side effects, it's crucial to contact your healthcare provider promptly.

Warning: Both gliclazide and metformin can cause hypoglycemia (low blood sugar) as a side effect, especially if the dosage is not adjusted correctly or if you skip meals.,,Gliclazide may cause weight gain in some individuals.,,Metformin may cause gastrointestinal side effects, such as nausea, vomiting, or diarrhea, especially when starting the medication.

Again, it's essential to follow your doctor's recommendations regarding dosage, administration, and any precautions associated with these medications. They will consider your medical history, overall health, and potential interactions with other medications you may be taking. If you experience any concerning side effects or have questions about your medications, don't hesitate to reach out to your healthcare provider.

Drug drug interaction: Gliclazide and metformin are both medications used to treat type 2 diabetes. They work differently to lower blood sugar levels and are often prescribed together to achieve better glycemic control.,,When taking multiple medications, there is a possibility of drug interactions, which could either enhance or reduce the effectiveness of the drugs or cause adverse effects. It's crucial to be cautious about potential interactions, especially if you are taking other medications or have specific health conditions.,,To determine possible interactions with Gliclazide and Metformin, it's best to consult a healthcare professional or pharmacist who has access to your complete medical history and current medication regimen. They can provide personalized advice and recommendations based on your individual health needs.

Please do not make any changes to your medication without consulting a healthcare professional first. They will be able to guide you appropriately to ensure the safe and effective management of your diabetes and overall health.

Drug food interaction: Gliclazide MR (Modified Release) and Metformin ER (Extended Release) are medications used to manage type 2 diabetes. While they generally don't have specific food interactions, it's essential to follow certain guidelines to ensure the effectiveness and safety of these medications.,,Take with meals: Gliclazide MR and Metformin ER are typically taken with meals. This is because the presence of food in the stomach can help reduce the risk of potential side effects, such as gastrointestinal upset. It can also help regulate the absorption of the medications.,,Avoid alcohol: Both Gliclazide and Metformin can cause low blood sugar levels (hypoglycemia), and alcohol can exacerbate this effect. Moreover, alcohol consumption can affect blood glucose levels, making diabetes management more challenging. It is best to avoid alcohol or consume it in moderation, after consulting with your healthcare provider.,,Be cautious with high-carbohydrate meals: While there are no specific food interactions, consuming large, high-carbohydrate meals can raise blood sugar levels. It is generally advisable to follow a balanced diet, rich in vegetables, lean proteins, and complex carbohydrates, while avoiding excessive intake of sugary and refined foods.,,Grapefruit: Grapefruit and its juice can interact with various medications, but there are no known interactions with Gliclazide or Metformin. However, if you have concerns, it's best to consult your healthcare provider.

Always follow the instructions provided by your healthcare professional and the medication's label. If you have any questions or concerns about your medication and diet, talk to your doctor or pharmacist for personalized advice based on your medical history and individual needs. They can provide guidance on how to best take your medications in conjunction with your diet to manage your diabetes effectively.

Drug disease interaction: Gliclazide (MR) and Metformin (ER) are commonly used medications to treat type 2 diabetes. They work in different ways to help control blood sugar levels in individuals with this condition.,,Type 2 Diabetes: Gliclazide (MR) is a sulfonylurea medication that stimulates the pancreas to release more insulin, which helps lower blood sugar levels. Metformin (ER) is a biguanide medication that improves insulin sensitivity and reduces glucose production in the liver. Both drugs are used to manage type 2 diabetes when lifestyle changes alone (diet and exercise) are insufficient.,,By combining Gliclazide (MR) and Metformin (ER), the aim is to provide better blood sugar control than using either drug alone, as they have complementary mechanisms of action.

It's important to note that all medications can have side effects, and the choice of medication and dosages should be determined by a healthcare professional based on the individual's specific health condition, medical history, and other factors. If you have any concerns or questions about the medications you are taking, it's essential to discuss them with your doctor or pharmacist.

Contraindications are situations where the use of a particular medication may be harmful or should be avoided due to specific medical conditions or risk factors. Contraindications for the combination of Gliclazide and Metformin may include:

Allergy or hypersensitivity to either Gliclazide or Metformin.,,Severe kidney impairment or kidney failure. Metformin can accumulate in the body when kidney function is impaired, leading to potential lactic acidosis, a serious condition.,,Liver disease or significant liver impairment, as this may affect the metabolism of the drugs.,,History of lactic acidosis or a predisposition to this condition.,,Certain heart conditions or heart failure.,,Alcohol abuse or excessive alcohol consumption. Alcohol may interact with both medications and increase the risk of lactic acidosis.

It's crucial to consult a qualified healthcare professional or a doctor for personalized advice regarding the use of any medications, including Gliclazide and Metformin. They can assess your specific medical history, current health status, and other medications you might be taking to determine if this combination is appropriate for you or if there are any potential contraindications. Always follow your healthcare provider's recommendations and never self-medicate or stop any medication without their guidance.

Follow Your Doctor's Instructions: Take Gliclazide and Metformin exactly as prescribed by your healthcare provider. Follow the recommended dosage, frequency, and duration of use.,,Allergy and Medication Interactions: Inform your doctor about any known allergies or other medications you are taking to avoid potential interactions.,,Blood Sugar Monitoring: Regularly monitor your blood sugar levels as advised by your doctor. This is especially important if you are on multiple medications to manage diabetes.,,Hypoglycemia (Low Blood Sugar): Gliclazide can sometimes cause hypoglycemia. Be aware of the signs and symptoms of low blood sugar and know how to treat it. Always carry a source of quick-acting glucose (like glucose tablets) in case of emergencies.,,Metformin and Lactic Acidosis: Metformin, particularly in higher doses or in individuals with kidney problems, can rarely lead to a serious condition called lactic acidosis. Inform your doctor if you have kidney issues and report any signs of lactic acidosis, such as muscle pain, weakness, difficulty breathing, or stomach discomfort.,,Alcohol and Gliclazide: Avoid excessive alcohol consumption while taking Gliclazide, as it can increase the risk of hypoglycemia.,,Kidney and Liver Function: Regularly check your kidney and liver function as directed by your healthcare provider, especially if you have pre-existing kidney or liver conditions.,,Avoiding Dehydration: Metformin can sometimes cause dehydration, so ensure you drink enough fluids, especially if you are unwell or experiencing diarrhea.,,Informing Healthcare Providers: Always inform other healthcare providers, including dentists or specialists, that you are taking Gliclazide and Metformin, as they may need to adjust their treatment plans accordingly.

Store this medicine at room temperature, away from sunlight and moisture.

Gliclazide (MR) and metformin (ER) are two medications commonly used to treat type 2 diabetes mellitus. Let's explore the uses and benefits of each medication.,,Gliclazide (MR) 60mg: Gliclazide is an oral antidiabetic medication that belongs to the class of sulfonylureas. It works by stimulating the pancreas to release insulin, which helps lower blood sugar levels. Here are its primary uses:Type 2 diabetes mellitus: Gliclazide is mainly prescribed for people with type 2 diabetes who have not achieved adequate blood sugar control through diet and exercise alone. It is typically used when lifestyle modifications and metformin are insufficient to control blood glucose levels.

Metformin (ER) 500mg:Metformin is an oral biguanide medication and is considered a first-line treatment for type 2 diabetes. It works by reducing the production of glucose by the liver and increasing the body's sensitivity to insulin. Here are its primary uses:Type 2 diabetes mellitus: Metformin is commonly prescribed as a first-line treatment for type 2 diabetes, especially for individuals who are overweight or obese. It helps improve insulin sensitivity and decreases glucose production by the liver, leading to better blood sugar control.,,Polycystic ovary syndrome (PCOS): Metformin is also used to manage hormonal imbalances and insulin resistance associated with polycystic ovary syndrome in women.,,Gestational diabetes: In some cases, metformin may be prescribed for women with gestational diabetes when diet and exercise alone are not sufficient to control blood sugar levels during pregnancy.

Combination therapy:The combination of Gliclazide (MR) 60mg and Metformin (ER) 500mg may be prescribed in cases where a single medication is not providing adequate glycemic control. Combining medications with different mechanisms of action can have a synergistic effect, leading to better blood sugar management. It's essential to follow your doctor's prescription and recommendations while taking these medications and to monitor blood sugar levels regularly.