category
Heart
composition
This drug contain Clopidogrel 75 mg
workings
Clopidogrel 75mg is a medication that belongs to the class of antiplatelet drugs. It works by inhibiting the function of platelets, which are blood cells responsible for forming clots to stop bleeding.
Clopidogrel works by blocking a specific receptor on the surface of platelets called the P2Y12 receptor. When platelets are activated, they release chemicals that cause the P2Y12 receptor to become active, leading to further platelet activation and the formation of blood clots.
By blocking the P2Y12 receptor, clopidogrel reduces platelet activation and prevents the formation of blood clots. This is particularly important in preventing blood clots that can cause heart attacks and strokes in people with a history of cardiovascular disease or those at risk for developing it.
It is important to note that clopidogrel should only be taken as directed by a healthcare provider, as it can increase the risk of bleeding and interact with other medications.
usage
Acute Coronary Syndrome: Clopidogrel is used along with aspirin to prevent blood clots in people with acute coronary syndrome, a condition where there is a sudden reduction in blood flow to the heart.,,Stroke: Clopidogrel is used to prevent blood clots in people who have had a stroke or a mini-stroke (transient ischemic attack).,,Peripheral Artery Disease: Clopidogrel is used to prevent blood clots in people with peripheral artery disease, a condition where there is reduced blood flow to the legs.,,Coronary Artery Stenting: Clopidogrel is used after coronary artery stenting, a procedure where a metal mesh tube is placed in the narrowed or blocked coronary artery to keep it open.,,Acute ST-Elevation Myocardial Infarction: Clopidogrel is used in combination with other medications to treat acute ST-elevation myocardial infarction, a type of heart attack that occurs when a blood clot completely blocks an artery supplying blood to the heart.,,It is important to note that Clopidogrel should only be taken under the guidance and prescription of a healthcare provider.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Bleeding: Clopidogrel can increase the risk of bleeding. Symptoms of bleeding can include easy bruising, prolonged bleeding from cuts, nosebleeds, and blood in urine or stool.,,Diarrhea: Some people taking clopidogrel may experience diarrhea, which can be mild or severe.,,Indigestion: Clopidogrel may cause stomach upset, nausea, and indigestion.,,Headache: Headache is a common side effect of clopidogrel, but it is usually mild and goes away on its own.,,Dizziness: Some people may experience dizziness while taking clopidogrel.,,Skin rash: In rare cases, clopidogrel can cause a skin rash or hives.,,Itching: Clopidogrel can sometimes cause itching without a rash.,,If you experience any of these side effects while taking clopidogrel, you should talk to your doctor. In some cases, your doctor may need to adjust your dosage or switch you to a different medication.
warnings
Warning: Clopidogrel is a medication used to prevent blood clots in individuals who have had a recent heart attack, stroke, or certain types of heart disease. However, like all medications, clopidogrel can cause side effects. Here are some warnings associated with taking clopidogrel 75mg:
Bleeding: Clopidogrel can increase the risk of bleeding, including gastrointestinal and intracranial bleeding. If you experience any signs of bleeding, such as bloody or tarry stools, vomiting blood, or prolonged bleeding from cuts, you should seek medical attention immediately.
Allergic reactions: Some people may develop an allergic reaction to clopidogrel, which can cause symptoms such as difficulty breathing, swelling of the face, lips, tongue or throat, and skin rash. If you experience any of these symptoms, stop taking clopidogrel and seek medical attention immediately.
Interaction with other medications: Clopidogrel can interact with other medications, such as blood thinners, nonsteroidal anti-inflammatory drugs (NSAIDs), and proton pump inhibitors (PPIs). It is important to inform your doctor or pharmacist about all the medications you are taking before starting clopidogrel.
Genetic testing: Some individuals may have a genetic variation that affects how they metabolize clopidogrel. Your doctor may recommend genetic testing to determine if you are at risk of poor clopidogrel metabolism and may need a different medication or a different dose.
Surgery: If you are scheduled to have surgery, it is important to inform your doctor that you are taking clopidogrel. You may need to stop taking clopidogrel temporarily before the surgery to reduce the risk of bleeding.
interactions
Drug drug interaction: There are many drugs that can interact with clopidogrel, a medication used to prevent blood clots in people with certain heart and blood vessel conditions. Some of the most important drug interactions to be aware of include:
Proton pump inhibitors (PPIs), such as omeprazole and esomeprazole, can reduce the effectiveness of clopidogrel. If you need to take a PPI, your doctor may recommend a lower dose or a different medication.,,Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, can increase the risk of bleeding when taken with clopidogrel.,,Anticoagulants, such as warfarin and heparin, can increase the risk of bleeding when taken with clopidogrel.,,Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and sertraline, can increase the risk of bleeding when taken with clopidogrel.,,Certain medications used to treat depression, such as tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs), can increase the risk of bleeding when taken with clopidogrel.
It is important to always tell your doctor and pharmacist about all the medications, vitamins, and supplements you are taking before starting clopidogrel or any other medication. They can help you determine if there are any potential drug interactions to be aware of.
Drug food interaction: Clopidogrel is an antiplatelet medication used to prevent blood clots in people with cardiovascular disease. Certain foods and drugs can interact with clopidogrel and affect its effectiveness or increase the risk of bleeding. Some foods that interact with clopidogrel include:
Grapefruit and grapefruit juice: Grapefruit and grapefruit juice can increase the level of clopidogrel in the blood, which may increase the risk of bleeding.,,Green leafy vegetables: Green leafy vegetables like spinach and kale are rich in vitamin K, which can interfere with the anti-clotting effects of clopidogrel.,,Cranberry juice: Cranberry juice may also increase the risk of bleeding when taken with clopidogrel.,,Alcohol: Drinking alcohol while taking clopidogrel can increase the risk of bleeding and should be avoided or limited.,,It is important to talk to your healthcare provider about any medications and foods you are taking before starting clopidogrel or making any changes to your diet.
Drug disease interaction: Clopidogrel is an antiplatelet medication that is commonly used to prevent blood clots in individuals who have had a recent heart attack or stroke, or who have certain types of cardiovascular disease.
Some of the diseases that may interact with Clopidogrel include:,,Bleeding disorders: Clopidogrel can increase the risk of bleeding in individuals with bleeding disorders.,,Liver disease: Clopidogrel is metabolized in the liver, and individuals with severe liver disease may have difficulty metabolizing the medication.,,Kidney disease: Clopidogrel is eliminated from the body through the kidneys, and individuals with severe kidney disease may have difficulty eliminating the medication.,,Gastric ulcers: Clopidogrel can increase the risk of bleeding in individuals with gastric ulcers.,,Recent surgery: Clopidogrel can increase the risk of bleeding after surgery.,,It's important to talk to your healthcare provider about any medical conditions you have before taking Clopidogrel or any other medication.
contraindications
Clopidogrel is a medication used to prevent blood clots in people with certain heart and blood vessel conditions. However, there are several contraindications to its use, including:
Active bleeding: Clopidogrel can increase the risk of bleeding, so it should not be used in people with active bleeding or a bleeding disorder.,,Severe liver disease: Clopidogrel is metabolized by the liver, so it may not be safe for people with severe liver disease.,,Hypersensitivity: Clopidogrel can cause allergic reactions in some people. If you have a history of hypersensitivity to clopidogrel or any of its components, you should not take this medication.,,Pregnancy and breastfeeding: Clopidogrel should be avoided during pregnancy and breastfeeding unless it is deemed absolutely necessary by a healthcare professional.,,Recent surgery or injury: Clopidogrel may increase the risk of bleeding in people who have recently had surgery or a serious injury.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Acute Coronary Syndrome: Clopidogrel is used along with aspirin to prevent blood clots in people with acute coronary syndrome, a condition where there is a sudden reduction in blood flow to the heart.,,Stroke: Clopidogrel is used to prevent blood clots in people who have had a stroke or a mini-stroke (transient ischemic attack).,,Peripheral Artery Disease: Clopidogrel is used to prevent blood clots in people with peripheral artery disease, a condition where there is reduced blood flow to the legs.,,Coronary Artery Stenting: Clopidogrel is used after coronary artery stenting, a procedure where a metal mesh tube is placed in the narrowed or blocked coronary artery to keep it open.,,Acute ST-Elevation Myocardial Infarction: Clopidogrel is used in combination with other medications to treat acute ST-elevation myocardial infarction, a type of heart attack that occurs when a blood clot completely blocks an artery supplying blood to the heart.,,It is important to note that Clopidogrel should only be taken under the guidance and prescription of a healthcare provider.