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capecitabine 500 mg

strip(s) of 10 tablets

1500 /-

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Cancer

composition

This drug contain Capecitabine 500 mg

workings

Capecitabine 500mg is an oral chemotherapy drug that is used to treat various types of cancers, including breast, colon, and rectal cancers. The active ingredient in capecitabine is a prodrug that is converted to 5-fluorouracil (5-FU) in the body.

5-FU is a cytotoxic (cell-killing) drug that works by inhibiting the growth of cancer cells. It does this by interfering with the synthesis of DNA and RNA, which are necessary for the growth and replication of cancer cells. Specifically, 5-FU inhibits the enzyme thymidylate synthase, which is responsible for producing the building blocks of DNA. By inhibiting this enzyme, 5-FU prevents cancer cells from dividing and growing.

Capecitabine is designed to be converted to 5-FU primarily in the cancer cells, which helps to target the drug to where it is needed most. The conversion occurs in two steps, with the first step occurring in the liver and the second step occurring in the tumor cells themselves. This targeted approach can help to minimize side effects and increase the effectiveness of the drug.,,Overall, Capecitabine 500mg is an important chemotherapy drug that works by inhibiting the growth of cancer cells, primarily through the action of its active metabolite, 5-FU.

usage

Capecitabine is a chemotherapy drug that is primarily used to treat various types of cancer, including breast, colorectal, and gastric cancer. It works by inhibiting the growth and spread of cancer cells in the body.,,Some of the specific uses of Capecitabine 500 mg include:

Breast cancer: Capecitabine is often used in combination with other chemotherapy drugs to treat advanced or metastatic breast cancer that has spread to other parts of the body.,,Colorectal cancer: It may be used as a single agent or in combination with other chemotherapy drugs to treat colorectal cancer that has spread to other parts of the body.,,Gastric cancer: Capecitabine may be used in combination with other chemotherapy drugs to treat advanced or metastatic gastric cancer.,,Pancreatic cancer: It may be used in combination with other chemotherapy drugs to treat pancreatic cancer that has spread to other parts of the body.,,Others: Capecitabine may also be used in the treatment of other cancers, such as head and neck cancer and ovarian cancer, among others.,,It is important to note that Capecitabine should only be used under the guidance of a qualified healthcare professional, as it can cause serious side effects and may interact with other medications.

directions

Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.

side effects

Nausea and vomiting,,Diarrhea,,Loss of appetite,,Mouth sores,,Fatigue,,Hair loss,,Hand-foot syndrome (pain, redness, and swelling of the hands and feet),,Skin rash,,Changes in taste,,Abdominal pain,,Fever,,Headache,,Dizziness,,Weakness,,Anemia,,Low white blood cell count,,Low platelet count.

warnings

Warning: Capecitabine is a medication used to treat cancer. Like all medications, it can cause side effects, and some of these can be serious. Here are some warnings associated with the use of Capecitabine:,,Risk of blood clots: Capecitabine can increase the risk of blood clots in some people. Contact your healthcare provider immediately if you develop symptoms such as swelling, pain, or warmth in a leg, chest pain, difficulty breathing, or sudden severe headache.,,Hand-foot syndrome: This is a common side effect of Capecitabine. It causes redness, swelling, and pain in the hands and feet, which can affect your ability to do daily activities. Contact your healthcare provider if you experience these symptoms.,,Diarrhea: Capecitabine can cause severe diarrhea, which can lead to dehydration and electrolyte imbalances. Contact your healthcare provider immediately if you experience diarrhea that lasts more than 24 hours, or if you have symptoms such as fever, abdominal pain, or bloody stools.,,Liver problems: Capecitabine can cause liver problems, which can be serious. Contact your healthcare provider if you experience symptoms such as yellowing of the skin or eyes, dark urine, or abdominal pain.,,Pregnancy: Capecitabine can harm an unborn baby. It is important to tell your healthcare provider if you are pregnant, or if you plan to become pregnant while taking Capecitabine.

It is important to follow your healthcare provider's instructions and to report any side effects or concerns promptly.kj

interactions

Drug drug interaction: There are several drugs that can interact with Capecitabine 500 mg. Some of the common ones include:

Warfarin: Capecitabine may increase the risk of bleeding when taken with Warfarin.,,Antacids: Antacids may reduce the absorption of Capecitabine, so it is recommended to avoid taking them within 2 hours before or after taking Capecitabine.,,Folic acid: Folic acid supplements may reduce the effectiveness of Capecitabine.,,Leucovorin: Leucovorin is sometimes given together with Capecitabine to enhance its effectiveness, but it may also increase the risk of side effects.,,Sorivudine: Sorivudine should not be taken with Capecitabine as it can cause severe side effects.

It is important to always inform your healthcare provider about all medications, supplements, and herbs you are taking before starting Capecitabine to avoid any potential drug interactions.

Drug food interaction: Capecitabine is an oral chemotherapy medication used in the treatment of various types of cancer. It works by interfering with the growth and spread of cancer cells in the body.,,There are some foods that may interact with Capecitabine and affect its absorption, metabolism, or effectiveness. Therefore, it is important to follow your doctor or pharmacist's instructions and any dietary recommendations they provide.,,One potential food interaction with Capecitabine is grapefruit and grapefruit juice. Grapefruit contains compounds that can inhibit an enzyme in the liver, which is responsible for metabolizing many drugs, including Capecitabine. This can lead to increased levels of the medication in the bloodstream and potentially increase the risk of side effects.,,Other foods that may interact with Capecitabine include:

Foods that are high in fat, which can reduce the absorption of Capecitabine.,,Foods that are high in calcium, such as dairy products or calcium supplements, which can reduce the effectiveness of Capecitabine.

It is important to talk to your doctor or pharmacist about any dietary restrictions or recommendations when taking Capecitabine to ensure that you are getting the most benefit from the medication.

Drug disease interaction: There are also certain conditions and diseases that may interact with Capecitabine, making it less effective or increasing the risk of side effects. Some of these include:

Kidney disease,,Liver disease,,Low white blood cell counts,,Low platelet counts,,Blood clotting disorders,,Coronary artery disease,,History of heart attack or stroke,,Diabetes,,Dehydration,,Infection.

It is important to inform your doctor about any medical conditions you have before taking Capecitabine, as well as any medications, supplements, or herbal remedies you are currently taking. Your doctor will be able to determine whether Capecitabine is safe for you and whether any adjustments need to be made to your treatment plan.

contraindications

Capecitabine is a medication used in the treatment of certain types of cancer, such as breast cancer and colorectal cancer. It is important to note that Capecitabine 500mg has several contraindications, which include:

Hypersensitivity: Capecitabine should not be used in patients who have a known hypersensitivity to the drug or any of its ingredients.,,Severe Renal Impairment: Capecitabine should be avoided in patients with severe renal impairment (creatinine clearance less than 30 mL/min).,,Pregnancy and lactation: Capecitabine is contraindicated in pregnancy and lactation.,,Dihydropyrimidine dehydrogenase (DPD) Deficiency: Capecitabine should be avoided in patients with known DPD deficiency as they are at increased risk of severe and life-threatening toxicity.,,Concurrent use with Sorivudine or its chemically related analogues: Capecitabine should not be used concomitantly with Sorivudine or its chemically related analogues as it may cause severe toxicity.,,Warfarin: Capecitabine may increase the anticoagulant effect of warfarin, and caution should be exercised when these drugs are used concomitantly.

It is important to inform your healthcare provider about any medical conditions or medications you are taking before starting Capecitabine treatment.

storage

Store this medicine at room temperature, away from sunlight and moisture.

directions use

Capecitabine is a chemotherapy drug that is primarily used to treat various types of cancer, including breast, colorectal, and gastric cancer. It works by inhibiting the growth and spread of cancer cells in the body.,,Some of the specific uses of Capecitabine 500 mg include:

Breast cancer: Capecitabine is often used in combination with other chemotherapy drugs to treat advanced or metastatic breast cancer that has spread to other parts of the body.,,Colorectal cancer: It may be used as a single agent or in combination with other chemotherapy drugs to treat colorectal cancer that has spread to other parts of the body.,,Gastric cancer: Capecitabine may be used in combination with other chemotherapy drugs to treat advanced or metastatic gastric cancer.,,Pancreatic cancer: It may be used in combination with other chemotherapy drugs to treat pancreatic cancer that has spread to other parts of the body.,,Others: Capecitabine may also be used in the treatment of other cancers, such as head and neck cancer and ovarian cancer, among others.,,It is important to note that Capecitabine should only be used under the guidance of a qualified healthcare professional, as it can cause serious side effects and may interact with other medications.

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