category
Respiratory
composition
This drug contain Formoterol fumarate 12mcg+ budesonide 400 mcg.
workings
Formoterol fumarate and budesonide are two active pharmaceutical ingredients commonly used in combination inhalers for the treatment of asthma and chronic obstructive pulmonary disease (COPD). They work synergistically to manage the symptoms of these respiratory conditions.
Budesonide (corticosteroid):Budesonide is a corticosteroid, a type of anti-inflammatory medication. It works by reducing inflammation and swelling in the airways. When inhaled, budesonide targets the lungs directly, where it exerts its anti-inflammatory effects. By reducing inflammation in the airways, it helps prevent and control asthma and COPD exacerbations (flare-ups).
Budesonide does not provide immediate relief of symptoms and is not a bronchodilator. Its effects may take several days to develop fully, so it is considered a maintenance medication, taken regularly even when the patient is not experiencing symptoms.
Formoterol fumarate (long-acting beta-agonist):Formoterol is a long-acting beta-agonist (LABA) bronchodilator. It acts on the beta-2 adrenergic receptors in the smooth muscles of the airways, causing them to relax. This bronchodilation opens up the airways, making it easier for the patient to breathe and relieving symptoms like shortness of breath and wheezing.
Formoterol's effects occur rapidly, providing quick relief of asthma or COPD symptoms. However, as a LABA, it is not intended for long-term control of inflammation. When used alone, LABAs can increase the risk of severe asthma attacks, which is why they are often combined with corticosteroids like budesonide.
Combination therapy (Formoterol fumarate + budesonide):The combination of formoterol fumarate and budesonide in a single inhaler offers the benefits of both rapid bronchodilation and long-term anti-inflammatory effects. This combination is commonly used in asthma and COPD management to achieve better symptom control and reduce the risk of exacerbations.
The bronchodilatory effect of formoterol helps provide immediate relief when needed, while budesonide's anti-inflammatory action works to prevent worsening of symptoms over time. This approach helps improve lung function, reduces the frequency of asthma or COPD attacks, and enhances overall disease management.
It is crucial for patients using combination inhalers to follow their prescribed treatment plans and not use them for acute asthma attacks. For acute exacerbations, patients should use short-acting bronchodilators (e.g., albuterol) as rescue medications as directed by their healthcare providers.
usage
Formoterol fumarate 12mcg + budesonide 400mcg is a combination medication used to manage asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients:,,Formoterol fumarate: This is a long-acting beta-agonist (LABA) bronchodilator. It works by relaxing the smooth muscles of the airways, making it easier to breathe. Formoterol provides rapid relief of bronchoconstriction and helps prevent exercise-induced bronchoconstriction.,,Budesonide: This is an inhaled corticosteroid (ICS) that reduces inflammation and swelling in the airways, which helps to prevent asthma attacks and COPD exacerbations. Budesonide works by decreasing the production of inflammatory substances in the respiratory system.,,The combination of formoterol and budesonide offers both quick relief of acute symptoms and long-term control of inflammation in conditions like asthma and COPD.
Uses of Formoterol fumarate 12mcg + budesonide 400mcg:,,Asthma: This combination medication is used as maintenance therapy in the treatment of asthma for patients whose asthma symptoms are not adequately controlled by a regular inhaled corticosteroid alone. It helps to reduce inflammation and bronchoconstriction, thus preventing asthma attacks and improving overall lung function.
Chronic Obstructive Pulmonary Disease (COPD): For patients with COPD who experience frequent exacerbations and have a history of inadequate response to bronchodilators alone, this combination medication can be prescribed. It helps to manage symptoms, reduce exacerbations, and improve lung function.
It is crucial to use this medication as prescribed by your healthcare provider and to follow their instructions carefully. If you have any concerns or questions about your treatment, do not hesitate to consult your healthcare provider. As with any medication, there may be potential side effects or interactions with other drugs, so it's essential to be aware of any precautions and warnings associated with this combination medication.
side effects
Common side effects:Headache,,Throat irritation,,Nausea,,Dizziness,,Tremors or shakiness,,Respiratory-related side effects:Cough,,Hoarseness,,Increased wheezing (paradoxical bronchospasm),,Cardiovascular side effects:Increased heart rate (tachycardia),,Palpitations,,Increased blood pressure,,Adrenal insufficiency: Budesonide is a corticosteroid, and using high doses for an extended period can affect the body's ability to produce its natural steroids. This can lead to adrenal insufficiency, which may result in fatigue, weakness, and other symptoms.,,Oral candidiasis (thrush): Long-term use of inhaled corticosteroids like budesonide can increase the risk of developing oral thrush, a fungal infection in the mouth.,,Osteoporosis: Prolonged use of high-dose corticosteroids may increase the risk of osteoporosis (bone weakening) and fractures, especially in older adults.,,Allergic reactions: Some individuals may experience allergic reactions to the medications, which can manifest as rash, itching, swelling, or difficulty breathing. If you experience any signs of an allergic reaction, seek immediate medical attention.
warnings
Warning: Formoterol fumarate and budesonide are medications used to manage asthma and chronic obstructive pulmonary disease (COPD). When combined in a single inhaler, they provide both long-acting bronchodilation (via formoterol) and anti-inflammatory effects (via budesonide). However, like all medications, they come with potential warnings and precautions. Here are some important warnings to be aware of:
Asthma-related death: In rare cases, using long-acting beta-agonists (LABAs) like formoterol (one of the components of the combination) may increase the risk of asthma-related death. This risk is more likely when LABAs are used without an inhaled corticosteroid, like budesonide (the other component of the combination). Therefore, this combination inhaler should only be used in patients who are not adequately controlled with other asthma-controller medications (e.g., inhaled corticosteroids) or whose disease severity clearly warrants the use of both an inhaled corticosteroid and a LABA.
Exacerbation of asthma: While formoterol and budesonide combination inhaler helps manage asthma symptoms, it may not be suitable for the treatment of acute bronchospasm or asthma exacerbations. Patients should have a short-acting beta-agonist (SABA) inhaler, such as albuterol, for rapid relief of acute symptoms.
Adrenal insufficiency: Prolonged use of corticosteroids, such as budesonide, may lead to adrenal insufficiency. This is more likely to occur when using high doses for an extended period. Patients who are being switched from oral corticosteroids to the inhaled combination should be closely monitored for signs of adrenal insufficiency.
Systemic effects: Inhaled corticosteroids, when used at high doses for prolonged periods, can lead to systemic effects, including adrenal suppression, reduced bone mineral density, cataracts, and increased risk of glaucoma. The risk of these effects is generally lower with inhaled corticosteroids compared to oral corticosteroids but may still be a concern, especially at higher doses.
Allergic reactions: Some individuals may experience hypersensitivity or allergic reactions to formoterol or budesonide. If any signs of an allergic reaction, such as rash, swelling, or difficulty breathing, occur, medical attention should be sought immediately.
Interactions: It's essential to inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal products, as some drugs may interact with formoterol and budesonide.
interactions
Drug drug interaction: Formoterol fumarate and budesonide are the active ingredients in a combination medication used to manage asthma and chronic obstructive pulmonary disease (COPD). The combination of these two drugs is commonly prescribed as an inhalation therapy. It is important to be aware of potential drug interactions when taking any medication. Here are some common drugs that may interact with Formoterol fumarate + budesonide:
Other Beta-2 Agonists: Since Formoterol is a long-acting beta-2 agonist, combining it with other beta-2 agonists may increase the risk of side effects.,,Other Corticosteroids: Budesonide is a corticosteroid, so combining it with other corticosteroids may increase the risk of corticosteroid-related side effects.,,Monoamine Oxidase Inhibitors (MAOIs): Formoterol may increase the cardiovascular effects of MAOIs, leading to an increased risk of hypertension.,,Tricyclic Antidepressants: Concurrent use with Formoterol may increase the risk of cardiovascular side effects.,,Diuretics: There may be an increased risk of hypokalemia (low potassium levels) when combining diuretics with Formoterol.,,Xanthine Derivatives: Combining Formoterol with xanthine derivatives (e.g., theophylline) may increase the risk of cardiac side effects.,,Beta-Blockers: Beta-blockers may inhibit the effects of Formoterol and worsen asthma symptoms in some patients. However, some beta-blockers are cardioselective and may have a lesser effect on the lungs.
Drug food interaction: Formoterol fumarate and budesonide are medications used to treat respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). They are often combined in a single inhaler to provide both long-acting bronchodilation and anti-inflammatory effects.,,When taking medications like formoterol fumarate 12mcg + budesonide 400mcg, it is generally recommended to avoid certain foods that may interact with these medications and affect their efficacy or safety. However, there are no specific dietary restrictions that are known to interact directly with formoterol fumarate or budesonide.,,That being said, there are some general considerations when taking these medications:
Grapefruit: Grapefruit and grapefruit juice can interact with certain medications by inhibiting enzymes that break down drugs in the body. However, there is no known interaction between grapefruit and formoterol fumarate or budesonide.,,Caffeine: High doses of caffeine may potentially increase the risk of side effects like tremors or palpitations when using formoterol. However, moderate caffeine intake from typical food and beverage sources is unlikely to cause significant interactions.,,Alcohol: Alcohol consumption may worsen some respiratory conditions, so it's generally advisable to moderate alcohol intake. However, there is no specific interaction between alcohol and formoterol fumarate or budesonide.,,Fatty meals: Some medications are absorbed better when taken with food, especially fatty meals. However, the absorption of formoterol fumarate and budesonide is not significantly affected by food.
As always, it's essential to follow the instructions and recommendations of your healthcare provider regarding the use of these medications. If you have any concerns about potential interactions, it's best to consult with your doctor or pharmacist for personalized advice.
Drug disease interaction: Formoterol fumarate and budesonide are medications used in combination to treat asthma and chronic obstructive pulmonary disease (COPD). This combination is typically prescribed as an inhaler, and it helps manage the symptoms of these respiratory conditions.
Asthma: Asthma is a chronic inflammatory disease that affects the airways in the lungs. It causes the airways to become swollen and narrowed, leading to symptoms like wheezing, coughing, chest tightness, and shortness of breath. Formoterol fumarate and budesonide combination inhaler helps in controlling the inflammation and bronchoconstriction associated with asthma, making it easier for patients to breathe.
Chronic Obstructive Pulmonary Disease (COPD): COPD is a group of progressive lung diseases that include chronic bronchitis and emphysema. In COPD, the airways become partially blocked, leading to difficulties in breathing. Formoterol fumarate and budesonide combination inhaler can be prescribed to manage symptoms and improve lung function in COPD patients.
It's important to note that this medication should only be used under the guidance and prescription of a healthcare professional. The dosage and duration of use will depend on the individual's condition and medical history. As with any medication, there may be potential side effects, so it's essential to discuss any concerns or questions with a healthcare provider.
contraindications
Formoterol fumarate and budesonide are medications used to manage asthma and chronic obstructive pulmonary disease (COPD). However, there are certain contraindications for the use of this combination medication (Formoterol fumarate 12mcg + budesonide 400 mcg) that should be taken into consideration:
Hypersensitivity: If a patient has a known hypersensitivity or allergy to formoterol fumarate, budesonide, or any other components of the medication, it is contraindicated to use this combination.,,Severe Allergic Reactions: Individuals with a history of severe hypersensitivity reactions to other medications or substances should avoid using this combination as it may trigger similar reactions.,,Status Asthmaticus: This refers to a severe and life-threatening asthma attack that does not respond to standard treatments. Formoterol and budesonide combination should not be used to treat acute exacerbations or status asthmaticus. Instead, immediate medical attention is required.,,Uncontrolled Asthma: The combination should not be used as a rescue medication for sudden asthma attacks. If a patient's asthma is not well-controlled, alternative treatment options or adjustments to their current treatment plan should be considered.,,COPD as the Only Diagnosis: This combination is specifically indicated for asthma patients and is not recommended for individuals with COPD as the sole diagnosis. Different medications may be more appropriate for managing COPD.,,Children under the Age Limit: The safety and efficacy of this combination have not been established in children below a certain age (usually 6 years old). Therefore, it may be contraindicated for use in younger children.
Always consult with a healthcare professional, such as a doctor or pharmacist, before starting or changing any medication. They can assess the individual's medical history and condition to determine the appropriateness of this combination medication and suggest the best treatment plan.
other
Formoterol fumarate (12mcg) + budesonide (400mcg) is a combination medication used to treat asthma and chronic obstructive pulmonary disease (COPD). It contains a long-acting beta-agonist (LABA) and an inhaled corticosteroid (ICS) to help control and manage respiratory symptoms. When using this medication, it's essential to follow safety guidelines to ensure its effectiveness and minimize potential risks. Here are some safety advice and tips:
Follow the prescribed dosage: Always take the medication exactly as prescribed by your healthcare provider. Never exceed or decrease the dosage without consulting them first.,,Use regularly: This medication is usually used on a daily basis, even if you don't have immediate symptoms. Do not stop or change the treatment regimen unless instructed by your healthcare provider.,,Understand its purpose: Formoterol fumarate and budesonide work differently to manage asthma and COPD symptoms. Formoterol is a bronchodilator that helps relax the airway muscles, while budesonide is an anti-inflammatory corticosteroid that reduces airway inflammation. Together, they provide better symptom control.,,Quick-relief inhaler: This combination medication is not intended as a quick-relief inhaler for sudden asthma or COPD attacks. Your healthcare provider should also prescribe a separate rescue inhaler for immediate symptom relief during emergencies.,,Report side effects: If you experience any side effects such as rapid heartbeat, chest pain, tremors, or changes in behavior, contact your healthcare provider immediately.,,Asthma action plan: Work with your healthcare provider to develop an asthma action plan that outlines what to do in different situations, such as during symptom exacerbations or exposure to triggers.,,Regular check-ups: Attend scheduled follow-up appointments with your healthcare provider. Regular check-ups are essential to monitor your condition, adjust treatment if necessary, and assess medication effectiveness.,,Inform healthcare providers: Make sure all your healthcare providers are aware of the medications you are taking, including Formoterol fumarate + budesonide. This includes primary care doctors, specialists, and emergency medical personnel.,,Storage: Keep the medication in a dry place at room temperature, away from direct sunlight and moisture. Follow the specific storage instructions provided by the manufacturer.,,Special considerations: Inform your healthcare provider about any other medical conditions you have, as well as any other medications you are taking, including over-the-counter drugs and dietary supplements. Some medications may interact with Formoterol fumarate + budesonide.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Formoterol fumarate 12mcg + budesonide 400mcg is a combination medication used to manage asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients:,,Formoterol fumarate: This is a long-acting beta-agonist (LABA) bronchodilator. It works by relaxing the smooth muscles of the airways, making it easier to breathe. Formoterol provides rapid relief of bronchoconstriction and helps prevent exercise-induced bronchoconstriction.,,Budesonide: This is an inhaled corticosteroid (ICS) that reduces inflammation and swelling in the airways, which helps to prevent asthma attacks and COPD exacerbations. Budesonide works by decreasing the production of inflammatory substances in the respiratory system.,,The combination of formoterol and budesonide offers both quick relief of acute symptoms and long-term control of inflammation in conditions like asthma and COPD.
Uses of Formoterol fumarate 12mcg + budesonide 400mcg:,,Asthma: This combination medication is used as maintenance therapy in the treatment of asthma for patients whose asthma symptoms are not adequately controlled by a regular inhaled corticosteroid alone. It helps to reduce inflammation and bronchoconstriction, thus preventing asthma attacks and improving overall lung function.
Chronic Obstructive Pulmonary Disease (COPD): For patients with COPD who experience frequent exacerbations and have a history of inadequate response to bronchodilators alone, this combination medication can be prescribed. It helps to manage symptoms, reduce exacerbations, and improve lung function.
It is crucial to use this medication as prescribed by your healthcare provider and to follow their instructions carefully. If you have any concerns or questions about your treatment, do not hesitate to consult your healthcare provider. As with any medication, there may be potential side effects or interactions with other drugs, so it's essential to be aware of any precautions and warnings associated with this combination medication.