category
Heart
composition
This drug contain Benidipine 4 mg.
workings
Benidipine is a calcium channel blocker (CCB) that is used to treat high blood pressure (hypertension). It works by blocking calcium channels in the smooth muscle cells of blood vessels, leading to the following mechanisms of action:
Relaxation of Blood Vessels: Calcium channel blockers like benidipine inhibit the influx of calcium into the smooth muscle cells of blood vessels. This causes the muscle cells to relax, reducing the tone or contraction of the blood vessels. As a result, the blood vessels dilate, allowing blood to flow more easily with reduced resistance. This vasodilation leads to a decrease in blood pressure.
Reduced Cardiac Workload: Benidipine also affects the heart by reducing its workload. By inhibiting calcium influx in cardiac muscle cells (cardiomyocytes), it decreases the contractility of the heart. As a result, the heart needs less energy to pump blood, which can be beneficial in conditions where the heart is working harder than it should due to high blood pressure.
Lowered Blood Pressure: The combined effect of vasodilation and reduced cardiac workload results in a decrease in systemic blood pressure. With the blood vessels more relaxed and the heart's workload reduced, the heart does not need to pump as forcefully, and the pressure against the blood vessel walls decreases.
Overall, by regulating calcium channels and blocking the entry of calcium into specific cells, benidipine helps lower blood pressure, improve blood flow, and reduce the strain on the heart. It is essential to take benidipine as prescribed by a healthcare professional and to follow up with regular check-ups to monitor blood pressure and overall health. As with any medication, potential side effects and drug interactions should be considered, and you should consult your doctor for personalized advice.
usage
Benidipine is a medication belonging to the dihydropyridine class of calcium channel blockers. It is primarily prescribed to treat hypertension (high blood pressure). The drug works by blocking the entry of calcium ions into smooth muscle cells of the blood vessels, leading to vasodilation and decreased peripheral resistance. Here are the main uses of Benidipine 4 mg:
Hypertension (High Blood Pressure): Benidipine is primarily used to lower blood pressure in individuals with hypertension. By relaxing and widening the blood vessels, it helps to reduce the pressure of blood against the arterial walls, making it easier for the heart to pump blood.
It's essential to take Benidipine as prescribed by your doctor and follow their instructions carefully. Depending on the severity of hypertension and individual response, the dosage may be adjusted.
It's important to note that while Benidipine is primarily used for hypertension, some off-label uses might be considered under the supervision of a healthcare professional. Always consult your doctor before using any medication for purposes other than what it is prescribed for.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Flushing: Some people may experience redness or warmth in the face and skin due to increased blood flow.,,Headache: Headaches are a common side effect of calcium channel blockers.,,Dizziness or lightheadedness: Benidipine can cause a drop in blood pressure, leading to feelings of dizziness or lightheadedness.,,Swelling of ankles and feet: Known as peripheral edema, this side effect occurs when fluid accumulates in the extremities.,,Fatigue: Feeling tired or lethargic is another possible side effect.,,Palpitations: Some individuals may experience a sensation of irregular or fast heartbeats.,,Nausea or stomach upset: Benidipine can cause gastrointestinal disturbances in some cases.,,Rash or itching: Allergic reactions to the medication may manifest as skin rash or itching.,,Muscle cramps: Muscle cramps or weakness may occur.,,Difficulty breathing: In rare cases, Benidipine may trigger shortness of breath or difficulty in breathing.
warnings
Warning: The usual recommended starting dose of Benidipine for hypertension is 4 mg once daily. However, please note that medication dosages and recommendations may vary depending on the patient's specific medical condition, age, and other factors. It's essential to follow your doctor's prescription and instructions carefully.
If you have been prescribed Benidipine or any other medication, make sure to take it as directed, and do not hesitate to ask your healthcare provider if you have any questions or concerns about its use. Additionally, inform your doctor about any other medications you are taking, as there might be potential drug interactions. If you experience any unexpected side effects or adverse reactions while taking Benidipine, contact your healthcare provider immediately.
Please remember that medical information is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with your healthcare provider for personalized guidance related to your specific health condition.
interactions
Drug drug interaction:Benidipine is a calcium channel blocker used to treat hypertension (high blood pressure). When taking any medication, there is a possibility of interactions with other drugs, supplements, or substances that could affect its effectiveness or increase the risk of side effects.
Some medications and substances that may interact with Benidipine include:
Other blood pressure medications: Taking multiple blood pressure-lowering drugs simultaneously can cause an excessive drop in blood pressure.,,Medications that affect liver enzymes: Benidipine is primarily metabolized in the liver, so drugs that affect liver enzymes could influence its effectiveness or increase the risk of side effects.,,Grapefruit and grapefruit juice: Grapefruit can interfere with the metabolism of certain drugs, including Benidipine, leading to higher levels of the drug in the body and an increased risk of side effects.,,CYP3A4 inhibitors and inducers: Benidipine is metabolized by the CYP3A4 enzyme. Drugs that inhibit or induce this enzyme could alter Benidipine's effects.,,Potassium-sparing diuretics: Combining Benidipine with potassium-sparing diuretics may increase the risk of hyperkalemia (high potassium levels in the blood).,,NSAIDs (nonsteroidal anti-inflammatory drugs): Some NSAIDs, when taken with Benidipine, may reduce the antihypertensive effect or increase the risk of kidney problems.
Drug food interaction: In the case of Benidipine, there are no specific foods that have been reported to cause serious interactions. However, certain types of food may have some effect on blood pressure, so it's generally a good idea to be mindful of your diet while taking antihypertensive medication. Here are some dietary tips to consider:
Grapefruit and grapefruit juice: Grapefruit and its juice can interact with many medications, including certain blood pressure medications. It may interfere with the metabolism of Benidipine, leading to increased blood levels of the drug and potentially causing adverse effects. It's best to avoid grapefruit products while taking Benidipine.,,High-potassium foods: Benidipine is a calcium channel blocker, and some studies suggest that high-potassium diets may reduce the effectiveness of calcium channel blockers in lowering blood pressure. While potassium is essential for your health, if you have concerns, consult your doctor or a registered dietitian for guidance on managing your potassium intake.,,Alcohol: Drinking excessive amounts of alcohol can affect blood pressure and may reduce the effectiveness of antihypertensive medications, including Benidipine. It's generally advisable to limit alcohol consumption while taking blood pressure medication.
Salt/sodium: Reducing sodium intake can be beneficial for individuals with hypertension, as it can help lower blood pressure. However, this is more of a general guideline for managing hypertension and not necessarily a specific interaction with Benidipine. Nonetheless, reducing salt intake is a good practice for those with high blood pressure.
Drug disease interaction: Some medical conditions that may interact with Benidipine or require caution when using this medication include:,,Heart conditions: Patients with certain heart conditions or heart-related issues may need to be monitored more closely while taking Benidipine. This includes conditions like heart failure, heart rhythm abnormalities, or recent heart attacks.,,Liver and kidney disorders: Benidipine is metabolized and eliminated from the body through the liver and kidneys. Patients with liver or kidney impairment may require dose adjustments or more careful monitoring while taking this medication.,,Hypotension (low blood pressure): Benidipine can cause a drop in blood pressure, so individuals with naturally low blood pressure or those at risk of developing hypotension should use this medication with caution.,,Peripheral edema: Some patients may experience peripheral edema (swelling in the legs or ankles) as a side effect of Benidipine. If you have a history of peripheral edema or other conditions related to fluid retention, your doctor should monitor you closely.,,Pregnancy and breastfeeding: Benidipine may not be suitable during pregnancy or while breastfeeding. It's essential to discuss the risks and benefits with a healthcare professional if you are pregnant or planning to become pregnant.,,Allergies: If you have known allergies to Benidipine or other calcium channel blockers, you should avoid using this medication.
contraindications
The standard dose of Benidipine is usually between 2 mg to 8 mg per day, depending on the patient's condition and response to the medication. However, I must emphasize that medical guidelines and drug contraindications may change over time, and it is essential to consult a healthcare professional or refer to the latest prescribing information for the most up-to-date and accurate details.
As of my last update, some general contraindications and precautions for the use of Benidipine 4 mg may include:
Allergy or hypersensitivity: Individuals with a known allergy or hypersensitivity to Benidipine or any other components of the medication should not take it.
Hypotension: Benidipine can cause a drop in blood pressure, so it should be used with caution in individuals with hypotension (abnormally low blood pressure).
Severe heart failure: Benidipine may worsen heart failure in some cases, so it is generally contraindicated in patients with severe heart failure.
Severe hepatic impairment: Patients with severe liver problems may have difficulty metabolizing the drug, and Benidipine should be avoided in such cases.
Pregnancy and breastfeeding: The safety of Benidipine during pregnancy and breastfeeding has not been well-established, so it is typically not recommended for use during these periods.
Grapefruit juice: Consumption of grapefruit juice can interfere with the metabolism of Benidipine, potentially leading to higher blood levels of the medication, which might increase the risk of side effects.
Always remember to consult with a healthcare professional before starting or stopping any medication, as they can provide personalized advice based on your specific medical history and condition. They will consider potential contraindications, drug interactions, and other factors to ensure the safe and effective use of Benidipine or any other medication.
other
Benidipine is a calcium channel blocker used to treat high blood pressure (hypertension). Here are some general safety tips when taking Benidipine 4 mg:
Take as Prescribed: Follow your doctor's instructions and take the medication exactly as prescribed. Avoid changing the dosage or stopping the medication without consulting your healthcare provider.,,Food and Timing: Benidipine can be taken with or without food, but try to take it at the same time each day to maintain a consistent level of the drug in your system.,,Avoid Grapefruit: Grapefruit and grapefruit juice can interact with Benidipine, potentially leading to increased levels of the medication in the bloodstream. It's best to avoid consuming grapefruit or its juice while taking Benidipine.,,Medical History: Inform your doctor about your complete medical history, especially if you have liver, kidney, or heart problems. This is important to ensure the medication is safe for you.,,Other Medications and Supplements: Make sure your doctor is aware of all other medications, supplements, or herbal remedies you are taking, as some may interact with Benidipine and cause adverse effects.,,Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking Benidipine, as its safety during pregnancy and lactation may not be established.,,Alcohol: Limit or avoid alcohol consumption while taking Benidipine, as it may increase the risk of dizziness or low blood pressure.,,Side Effects: Be aware of possible side effects such as dizziness, headache, swelling, or flushing. If you experience any severe or persistent side effects, contact your healthcare provider immediately.,,Blood Pressure Monitoring: Regularly monitor your blood pressure to ensure the medication is effectively controlling your hypertension.,,Missed Dose: If you miss a dose, take it as soon as you remember, but if it's close to the time of your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.,,Always consult your healthcare provider if you have any questions or concerns about taking Benidipine or any other medication. They can provide personalized advice based on your specific medical condition and history.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Benidipine is a medication belonging to the dihydropyridine class of calcium channel blockers. It is primarily prescribed to treat hypertension (high blood pressure). The drug works by blocking the entry of calcium ions into smooth muscle cells of the blood vessels, leading to vasodilation and decreased peripheral resistance. Here are the main uses of Benidipine 4 mg:
Hypertension (High Blood Pressure): Benidipine is primarily used to lower blood pressure in individuals with hypertension. By relaxing and widening the blood vessels, it helps to reduce the pressure of blood against the arterial walls, making it easier for the heart to pump blood.
It's essential to take Benidipine as prescribed by your doctor and follow their instructions carefully. Depending on the severity of hypertension and individual response, the dosage may be adjusted.
It's important to note that while Benidipine is primarily used for hypertension, some off-label uses might be considered under the supervision of a healthcare professional. Always consult your doctor before using any medication for purposes other than what it is prescribed for.