category
Antibiotic
composition
This is the combination of two antibiotic drug ie. sulfamethoxazole 100 mg + trimethoprim 20 mg
workings
Sulfamethoxazole 100 mg and trimethoprim 20 mg are antibiotics that work together to inhibit the growth of bacteria. Sulfamethoxazole is a sulfonamide antibiotic that interferes with the bacterial enzyme dihydropteroate synthase, which is necessary for the synthesis of folic acid. Trimethoprim, on the other hand, is a dihydrofolate reductase inhibitor that blocks the conversion of dihydrofolic acid to tetrahydrofolic acid, which is necessary for the synthesis of nucleic acids and proteins. Together, these two antibiotics work to inhibit bacterial growth by disrupting two different steps in the bacterial folate metabolism pathway.
usage
Bacterial infections: urinary tract infections,, respiratory infections,,ear infections.
directions
Sulfamethoxazole 100 mg + trimethoprim 20 mg is a liquid medication that contains a combination of two active ingredients, sulfamethoxazole and trimethoprim. Sulfamethoxazole is a sulfonamide antibiotic that works by inhibiting the growth of bacteria, while trimethoprim is a synthetic antibacterial agent that works by blocking the production of certain enzymes that are essential for the survival of bacteria. Together, these two ingredients are effective in treating a wide range of bacterial infections, such as urinary tract infections, ear infections, and respiratory tract infections.
side effects
Nausea,,Diarrhea,,Loss of appetite,,Dizziness,,Headache,,Stomach pain,,Vomiting,,Skin rash or itching,,Discoloration of urine,,Severe allergic reactions (rash, hives, itching,, difficulty breathing,,tightness in the chest,,swelling of the mouth, face, lips, or tongue),,Blood disorders (anemia, low white blood cell count, low platelet count),,Liver dysfunction,,Jaundice (yellowing of the skin or eyes),,Severe stomach or abdominal cramps,,Severe or persistent diarrhea (may be bloody),,Unusual changes in the amount or frequency of urination,,Sore throat, fever, chills, or other signs of infection
warnings
Warning: It is important to note that sulfamethoxazole and trimethoprim is not effective against viral infections and should not be used to treat conditions such as the common cold or flu. Additionally, long-term use of this medication may increase the risk of developing antibiotic-resistant bacteria, so it should only be used as directed by a healthcare provider.
interactions
Drug drug interaction : Drug interactions with sulfamethoxazole 100 mg + trimethoprim 20 mg may include:,,Warfarin: This combination may increase the risk of bleeding when taken with warfarin.,,Methotrexate: This combination may increase the risk of methotrexate toxicity.,,Phenytoin: This combination may decrease the effectiveness of phenytoin, which is used to treat seizures.,,Folic acid: This combination may decrease the effectiveness of folic acid, which is used to treat anemia.,,Digoxin: This combination may increase the risk of digoxin toxicity.,,Probenecid: This combination may increase the risk of kidney damage.
Drug food interaction : Vitamin K: sulfamethoxazole 100 mg + trimethoprim 20 mg can decrease the effectiveness of vitamin K, which is needed for proper blood clotting. If you take vitamin K supplements or consume foods high in vitamin K (such as leafy green vegetables), you should talk to your doctor about the appropriate dosage.,,Folic acid: sulfamethoxazole 100 mg + trimethoprim 20 mg can decrease the absorption of folic acid, which is needed for proper cell growth and development. If you take folic acid supplements or consume foods high in folic acid (such as leafy green vegetables, fortified cereals, and beans), you should talk to your doctor about the appropriate dosage.,,Alcohol: sulfamethoxazole 100 mg + trimethoprim 20 mg can increase the risk of side effects when taken with alcohol. It is recommended to avoid alcohol while taking this medication.,,Antacids: sulfamethoxazole 100 mg + trimethoprim 20 mg can decrease the effectiveness of antacids, which are used to neutralize stomach acid. It is recommended to take antacids at least 2 hours before or after taking sulfamethoxazole 100 mg + trimethoprim 20 mg.
Drug disease interaction : Renal Impairment: Sulfamethoxazole + trimethoprim can cause renal dysfunction and may lead to increased levels of creatinine and urea in the blood. It is contraindicated in patients with severe renal impairment.,,Hematological disorders: This combination can cause a decrease in the number of white blood cells, red blood cells, and platelets. It should be used with caution in patients with a history of blood disorders.,,Hyperkalemia: Sulfamethoxazole + trimethoprim can cause an increase in potassium levels in the blood, which can be dangerous for patients with kidney or heart disease.,,Metabolic acidosis: This combination can cause a decrease in the pH of the blood, leading to metabolic acidosis. It should be used with caution in patients with metabolic disorders.
contraindications
Inform your healthcare provider if you have any allergies or are taking any other medications.,,Always consult your healthcare provider before using this medication if you are pregnant or breastfeeding.,,Avoid consuming alcohol while taking this medication.
other
Do not cover the treated area unless advised by the doctor.
lifestyle
Do regular exercise such as cyclingbody walkingbody joggingbody dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.Avoid consumption of alcohol and quit smoking.
storage
Keep the medication in a cool, dry place, away from light and moisture.
directions use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it