category
Heart
composition
This drug contain Isosorbide mononitrate 20 mg
workings
Isosorbide dinitrate 20 mg is a medication that is used to prevent and treat chest pain (angina) caused by coronary artery disease. It works by relaxing and widening the blood vessels in the body, which reduces the workload on the heart and improves blood flow to the heart and other organs.
Specifically, isosorbide dinitrate is converted into nitric oxide (NO) in the body, which then activates an enzyme called guanylate cyclase. This enzyme produces a substance called cyclic guanosine monophosphate (cGMP), which causes the smooth muscles in the blood vessels to relax and widen. This allows more blood to flow through the vessels, which reduces the workload on the heart and relieves chest pain.
Isosorbide dinitrate is typically taken by mouth in tablet form, and the usual dose for angina is 5 to 20 milligrams (mg) every 6 hours as needed. However, the specific dose and frequency of use may vary depending on individual circumstances and the severity of the condition. It is important to follow the instructions of a healthcare provider when taking this medication.
usage
Isosorbide dinitrate is a medication that is primarily used to treat angina (chest pain). Here are some of the uses of isosorbide dinitrate 20 mg:
Angina: Isosorbide dinitrate is used to relieve the symptoms of angina, which include chest pain, tightness, or pressure. It works by relaxing the blood vessels, which allows more blood and oxygen to flow to the heart.,,Heart Failure: Isosorbide dinitrate is sometimes used in combination with other medications to treat heart failure. It helps to reduce the workload on the heart by widening the blood vessels, which can improve blood flow and reduce the amount of work the heart has to do.,,Hypertension: Isosorbide dinitrate can also be used to treat high blood pressure. It works by relaxing the blood vessels, which helps to lower blood pressure.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Headache,,Dizziness or lightheadedness,,Flushing (redness and warmth of the skin),,Nausea or vomiting,,Weakness or fatigue,,Dry mouth,,Blurred vision.
Less common side effects may include:,,Fainting or loss of consciousness,,Rapid or irregular heartbeat,,Shortness of breath,,Swelling of the face, hands, feet, or ankles,,Rash or itching.
warnings
Warning: Isosorbide dinitrate 20 mg is a medication used to prevent and treat chest pain (angina) caused by reduced blood flow to the heart. It works by relaxing and widening blood vessels, allowing more blood and oxygen to flow to the heart.
However, like all medications, isosorbide dinitrate can cause side effects. Common side effects may include headache, dizziness, lightheadedness, nausea, and flushing. These side effects are usually mild and go away on their own.
In rare cases, isosorbide dinitrate can cause more serious side effects, such as a rapid or irregular heartbeat, chest pain, fainting, and severe headache. If you experience any of these symptoms, seek medical attention immediately.
It is important to take isosorbide dinitrate as prescribed by your doctor and not to exceed the recommended dosage. If you have any questions or concerns about taking isosorbide dinitrate, talk to your healthcare provider.
interactions
Drug drug interaction: Isosorbide dinitrate 20 mg can interact with several drugs, including:
Phosphodiesterase-5 inhibitors (PDE-5 inhibitors) like sildenafil, tadalafil, and vardenafil used for the treatment of erectile dysfunction. Concomitant use of isosorbide dinitrate with PDE-5 inhibitors can cause a severe drop in blood pressure.,,Beta-blockers like propranolol and metoprolol used for the treatment of hypertension and other heart conditions. Concomitant use of isosorbide dinitrate with beta-blockers can cause an increased risk of hypotension and low blood pressure.,,Calcium channel blockers like diltiazem and verapamil used for the treatment of hypertension and angina. Concomitant use of isosorbide dinitrate with calcium channel blockers can cause an increased risk of hypotension and low blood pressure.,,Riociguat, a medication used to treat pulmonary arterial hypertension (PAH). Concomitant use of isosorbide dinitrate with riociguat can cause severe hypotension.,,It is important to inform your healthcare provider about all the medications, supplements, and herbs you are taking to avoid any potential drug interactions.
Drug food interaction: Isosorbide dinitrate is a medication used to prevent chest pain (angina) in patients with heart conditions. There are certain foods that can interact with Isosorbide dinitrate and affect its effectiveness or cause side effects.,,One of the most important food interactions to be aware of is grapefruit juice. Grapefruit juice can increase the level of Isosorbide dinitrate in the blood, leading to an increased risk of side effects such as headache, dizziness, and low blood pressure.,,Other foods that may interact with Isosorbide dinitrate include alcohol, which can also increase the risk of side effects such as dizziness and low blood pressure. Additionally, high-fat meals may reduce the absorption of Isosorbide dinitrate, reducing its effectiveness.,,It is important to talk to your doctor or pharmacist about any potential food interactions with Isosorbide dinitrate, and to follow their instructions regarding how to take the medication with or without food.
Drug disease interaction: Isosorbide dinitrate is a medication used to treat and prevent chest pain (angina) in people with coronary artery disease. It works by relaxing and widening blood vessels, which improves blood flow and reduces the workload on the heart.,,Isosorbide dinitrate is also used to treat heart failure and to relieve symptoms of congestive heart failure such as shortness of breath and swelling in the legs. Additionally, it is used in the treatment of high blood pressure in the blood vessels that supply the lungs (pulmonary hypertension).,,It is important to note that isosorbide dinitrate should not be used to treat a heart attack. If you are experiencing symptoms of a heart attack, seek immediate medical attention.
contraindications
Isosorbide dinitrate is a medication used to prevent angina (chest pain) caused by coronary artery disease. Contraindications are conditions or situations where a medication should not be used or should be used with caution.
Here are some contraindications for Isosorbide dinitrate 20 mg:,,Hypersensitivity: Isosorbide dinitrate should not be used in patients who have a known hypersensitivity to the medication or to any of its components.,,Severe anemia: Isosorbide dinitrate is contraindicated in patients with severe anemia because it can worsen symptoms.,,Glaucoma: Isosorbide dinitrate can increase intraocular pressure, which can worsen the symptoms of glaucoma.,,Hypotension: Isosorbide dinitrate can cause a drop in blood pressure, and therefore it should be used with caution in patients with hypotension.,,Use of sildenafil or other phosphodiesterase inhibitors: Concurrent use of Isosorbide dinitrate with sildenafil or other phosphodiesterase inhibitors can cause severe hypotension and is contraindicated.,,It is important to note that this is not a complete list of contraindications for Isosorbide dinitrate. Always consult with a healthcare provider before taking any medication.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Isosorbide dinitrate is a medication that is primarily used to treat angina (chest pain). Here are some of the uses of isosorbide dinitrate 20 mg:
Angina: Isosorbide dinitrate is used to relieve the symptoms of angina, which include chest pain, tightness, or pressure. It works by relaxing the blood vessels, which allows more blood and oxygen to flow to the heart.,,Heart Failure: Isosorbide dinitrate is sometimes used in combination with other medications to treat heart failure. It helps to reduce the workload on the heart by widening the blood vessels, which can improve blood flow and reduce the amount of work the heart has to do.,,Hypertension: Isosorbide dinitrate can also be used to treat high blood pressure. It works by relaxing the blood vessels, which helps to lower blood pressure.