category
Heart
composition
This drug contain Atorvastatin 10 mg + fenofibrate 160 mg
workings
Atorvastatin and fenofibrate are two different medications that are often used in combination to lower cholesterol levels in people who have high cholesterol or are at risk of developing cardiovascular disease.
Atorvastatin belongs to a class of drugs called HMG-CoA reductase inhibitors, commonly known as statins. Statins work by blocking the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the liver. By reducing cholesterol production, atorvastatin helps to lower the levels of LDL (bad) cholesterol in the blood and increase the levels of HDL (good) cholesterol.
Fenofibrate belongs to a class of drugs called fibrates. Fibrates work by activating an enzyme called lipoprotein lipase, which helps to break down triglycerides (a type of fat) in the blood. Fenofibrate also helps to increase the levels of HDL cholesterol and reduce the levels of LDL cholesterol.
When taken together, atorvastatin and fenofibrate can work synergistically to provide more comprehensive lipid-lowering effects. By targeting different aspects of lipid metabolism, the combination therapy can help to reduce the overall risk of cardiovascular disease in patients with high cholesterol. However, it is important to note that this combination therapy should only be used under the guidance of a healthcare professional and should be regularly monitored to ensure safety and efficacy.
usage
Atorvastatin and fenofibrate are two different medications that are commonly used to treat high levels of cholesterol and triglycerides in the blood.
Atorvastatin is a medication that belongs to a class of drugs called statins. It works by blocking an enzyme in the liver that is responsible for producing cholesterol. Atorvastatin can help lower LDL ("bad") cholesterol and triglycerides, while also increasing HDL ("good") cholesterol.
Fenofibrate, on the other hand, is a medication that belongs to a class of drugs called fibrates. It works by reducing the production of triglycerides in the liver and increasing the breakdown of triglycerides in the blood. Fenofibrate can help lower triglycerides and increase HDL cholesterol.
Combining atorvastatin and fenofibrate can have a synergistic effect in treating dyslipidemia, a condition characterized by abnormal levels of cholesterol and/or triglycerides in the blood. This combination medication is typically used to treat patients with mixed dyslipidemia, where both cholesterol and triglycerides are elevated.
The use of atorvastatin 10mg and fenofibrate 160mg can help improve lipid profiles, reducing the risk of cardiovascular diseases such as heart attacks and strokes. However, the use of these medications should always be discussed with a healthcare professional, as they may interact with other medications and have potential side effects.
directions
Swallow the tablets/capsule whole, do not crush or chew.,,Follow your doctor's instructions for adjusting your dose.
side effects
Headache,,Muscle aches or weakness,,Nausea or vomiting,,Diarrhea,,Constipation,,Stomach pain,,Skin rash.
Some common side effects of fenofibrate include:
Nausea or vomiting,,Abdominal pain,,Back pain,,Headache,,Muscle pain or weakness,,Skin rash,,Increased risk of gallstones.
warnings
Warning: Atorvastatin 10 mg and fenofibrate 160 mg are medications commonly used to treat high cholesterol and triglyceride levels in the blood. However, the combination of these two medications may increase the risk of serious side effects, such as:
Muscle pain or weakness: This is a rare but serious side effect that can lead to muscle damage, kidney failure, and even death.,,Liver problems: Atorvastatin and fenofibrate can both cause liver damage, especially in people who have pre-existing liver disease.,,Increased risk of bleeding: Fenofibrate can increase the risk of bleeding, especially in people who take blood thinners or have bleeding disorders.,,Digestive problems: Both medications can cause digestive problems such as nausea, diarrhea, and stomach pain.,,Increased risk of gallstones: Fenofibrate can increase the risk of gallstones, especially in women.
interactions
Drug drug interaction: There are several drugs that may interact with the combination of atorvastatin 10 mg and fenofibrate 160 mg. Here are some examples:
Warfarin: Atorvastatin and fenofibrate can both increase the risk of bleeding when taken with warfarin, a blood-thinning medication.
Cyclosporine: Atorvastatin and fenofibrate may increase the levels of cyclosporine in the blood, which can lead to toxic effects.
Gemfibrozil: Gemfibrozil is another medication used to lower cholesterol and triglycerides. When taken with atorvastatin and fenofibrate, it can increase the risk of muscle damage and kidney problems.
Clarithromycin: Clarithromycin is an antibiotic that can increase the levels of atorvastatin in the blood, increasing the risk of side effects.
Colchicine: Atorvastatin and fenofibrate may increase the levels of colchicine in the blood, which can lead to toxic effects.
It is important to always consult with your doctor or pharmacist before taking any new medication, including over-the-counter drugs and supplements, to avoid potential drug interactions.
Drug food interaction: Atorvastatin and fenofibrate are medications used to lower cholesterol levels in the blood. There are certain foods that can interact with these medications and affect their efficacy or cause side effects.
Atorvastatin is usually taken on an empty stomach, but it can be taken with food. However, it is important to avoid grapefruit and grapefruit juice while taking atorvastatin as it can increase the levels of the medication in the blood and lead to serious side effects.
Fenofibrate is usually taken with food to improve its absorption and reduce the risk of stomach upset. It is important to avoid alcohol and high-fat meals while taking fenofibrate as they can increase the risk of liver problems.
Overall, it is important to follow the dietary instructions provided by your doctor or pharmacist when taking atorvastatin and fenofibrate, and to inform them of any changes in your diet or medication regimen.
Drug disaese interaction: Atorvastatin and fenofibrate are medications used to treat high cholesterol and triglyceride levels in the blood. Atorvastatin belongs to a class of drugs called statins, which work by reducing the production of cholesterol in the liver, while fenofibrate belongs to a class of drugs called fibrates, which work by reducing the production of triglycerides in the liver.
When used together, atorvastatin and fenofibrate can interact and increase the risk of muscle damage, including a rare but serious condition called rhabdomyolysis. This risk is higher in people with kidney problems or who are taking other medications that increase the risk of rhabdomyolysis.
Therefore, it is important to take atorvastatin and fenofibrate only under the supervision of a healthcare provider who can monitor for potential side effects and adjust the dosage or treatment plan as needed.
contraindications
Atorvastatin and fenofibrate are two different medications that are often prescribed together to manage lipid disorders, such as high cholesterol and triglycerides. However, there are several contraindications for the use of these medications together or separately.
Some contraindications for atorvastatin include:
Hypersensitivity to atorvastatin or any of its components,,Active liver disease or unexplained persistent elevations in hepatic transaminases,,Pregnancy or breastfeeding.
Some contraindications for fenofibrate include:
Hypersensitivity to fenofibrate or any of its components,,Severe kidney disease,,Gallbladder disease,,Liver disease, including biliary cirrhosis and unexplained persistent liver function abnormalities,,Pregnancy or breastfeeding.
storage
Store this medicine at room temperature, away from sunlight and moisture.
directions use
Atorvastatin and fenofibrate are two different medications that are commonly used to treat high levels of cholesterol and triglycerides in the blood.
Atorvastatin is a medication that belongs to a class of drugs called statins. It works by blocking an enzyme in the liver that is responsible for producing cholesterol. Atorvastatin can help lower LDL ("bad") cholesterol and triglycerides, while also increasing HDL ("good") cholesterol.
Fenofibrate, on the other hand, is a medication that belongs to a class of drugs called fibrates. It works by reducing the production of triglycerides in the liver and increasing the breakdown of triglycerides in the blood. Fenofibrate can help lower triglycerides and increase HDL cholesterol.
Combining atorvastatin and fenofibrate can have a synergistic effect in treating dyslipidemia, a condition characterized by abnormal levels of cholesterol and/or triglycerides in the blood. This combination medication is typically used to treat patients with mixed dyslipidemia, where both cholesterol and triglycerides are elevated.
The use of atorvastatin 10mg and fenofibrate 160mg can help improve lipid profiles, reducing the risk of cardiovascular diseases such as heart attacks and strokes. However, the use of these medications should always be discussed with a healthcare professional, as they may interact with other medications and have potential side effects.