Vildagliptin 100 mg is an oral medicine belonging to the category of antidiabetic drugs and is used to manage type 2 diabetes mellitus.

More Common  

1. Difficulty with swallowing 
2. Dizziness 
3. Fast heartbeat 
4. Hives, itching, skin rash 
5. Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue 
6. Tightness in the chest 
7. Trouble breathing 
8. Unusual tiredness or weakness 

Less Common 

1. Hypoglycemia (especially when used with other medications) 
2. Swelling of the face, lips, or eyelids 
3. Heartburn 
4. Liver enzyme elevation 

Your body is like a classroom, and sugar is homework that helps students (your cells) do their best. Insulin is a kind helper who gives homework to every student, but in diabetes, some students stop accepting it, so the homework piles up in the teacher’s desk (your blood). There are two smart helpers, GLP-1 and GIP, who remind students to take their homework after lunch, but a troublemaker called DPP-4 makes them leave too soon. Vildagliptin is like a hall monitor who stops the troublemaker so the smart helpers can stay longer and guide the classroom better. This way, the body uses sugar properly, and everything runs more smoothly.

Pregnancy

Due to a lack of studies on the effects of vildagliptin on the fetus, its safety is not clearly established. Therefore, if you are pregnant or planning to conceive, inform your doctor.

Breastfeeding

Small amounts of vildagliptin pass into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should stop breastfeeding or stop vildagliptin.

Kidney and Liver Problems

Patients suffering from kidney and liver problems are more prone to kidney and liver damage as the drug is made into a less toxic form in the liver and kidney, so consult a doctor before using them.

Avoid alcohol and smoking simultaneously, as they may affect the drug’s action and show an effect on blood glucose levels by affecting the liver and pancreas. It can sometimes increase blood sugar levels and sometimes decrease blood sugar levels.

Avoid taking Vildagliptin 100 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

(2S)-1-[2-[(3-hydroxyadamantan-1-yl) amino]acetyl] pyrrolidine-2-carbonitrile

Daily dose

Take Vildagliptin exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 400 mg of vildagliptin per day, as it may cause severe overdosing effects like extreme dizziness, confusion, low blood pressure, liver damage, low blood sugar levels, swelling, muscle damage, and seizures. Immediately give the patient fruit or glucose-containing liquids and sugary foods to minimize the effects.

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

1. Take Vildagliptin exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Vildagliptin without your doctor’s approval, even if you feel better. 
3. If you forget to take Vildagliptin, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Vildagliptin is a medication taken by type 2 diabetes patients to control blood sugar level. After eating, our body releases helpful hormones that tell the pancreas to make insulin and stop sugar production, but these hormones don’t last long. Vildagliptin helps these hormones stay active longer so the body can use sugar more effectively. It can be taken with or without food and is often used alongside other diabetes medicines. Most people tolerate it well, but some may feel tired, get headaches, or have minor stomach issues. Rarely, it can affect the liver or cause serious problems like swelling or pancreatitis, so doctors usually test your from time to time. It’s not suitable for people with severe liver problems, type 1 diabetes, or those who’ve had pancreas trouble. Alcohol and other sugar-lowering drugs might make its effects stronger, so it’s best to use them cautiously and talk to a healthcare provider before combining anything.

What is the maximum dose of vildagliptin per day?

It is not recommended to take more than 400 mg of vildagliptin per day, as it may cause severe overdosing effects like extreme dizziness, confusion, low blood pressure, liver damage, low blood sugar levels, swelling, muscle damage, and seizures. Immediately give the patient fruit or glucose-containing liquids and sugary foods to minimize the effects.

What are the side effects of vildagliptin 50 mg?

Vildagliptin is a pill taken by people with type 2 diabetes to help keep their blood sugar levels under control. Most people tolerate it well, but some may get common side effect like feeling tired or headaches or have minor stomach issues.

What is the mechanism of action of vildagliptin?

Your body is like a classroom, and sugar is homework for your cells. Insulin helps deliver the homework, but in diabetes, some cells stop accepting it, so sugar builds up in the blood. GLP-1 and GIP are helpers that remind cells to take the sugar, but DPP-4 makes them leave too soon. Vildagliptin stops DPP-4, so the helpers stay longer and help the body use sugar better.

What are the uses of vildagliptin?

Vildagliptin is an oral antidiabetic medicine used to treat type 2 diabetes by promoting the insulin production and inhibiting an insulin-killing enzyme known as dipeptidyl peptidase.

1. European Medicines Agency. Galvus: EPAR—Product Information. EMA; [cited 2025 Jul 18]. Available from. 
2. Medicover Hospitals. Vildagliptin: Uses, Dosage, Side Effects, Price. Medicover Hospitals; [cited 2025 Jul 18]. Available from. 
3. DrugBank. Vildagliptin (DB04876). DrugBank Online; [cited 2025 Jul 18]. Available from. 
4. Gallwitz B. Clinical Use of DPP-4 Inhibitors. Frontiers in Diabetes. 2009;19:137–152. [cited 2025 Jul 18]. Available from. 
5. Drugs.com. Galvus 50mg tablets —Summary of Product Characteristics (SPC). Drugs.com UK; [cited 2025 Jul 18]. Available from.