Solifenacin 5 mg (ER) is an oral medicine belonging to the category of muscarinic receptor antagonists and is used for the following indications:

1. Overactive bladder 
2. Bladder leakage 
3. Unable to hold urine 

More Common  

1. Bladder pain 
2. Bloody or cloudy urine 
3. Blurred vision 
4. Difficult, burning, or painful urination 
5. Dizziness 
6. Frequent urge to urinate 
7. Headache 
8. Lower back or side pain 
9. Nervousness 
10. Pounding in the ears 
11. Slow, fast, or irregular heartbeat 

Less Common 

1. Severe stomach pain, or constipation for 3 days or longer; 
2. Pain or burning when you urinate; 
3. Headache, confusion, drowsiness, hallucinations; 
4. Vision changes, eye pain, or seeing halos around lights; 
5. Little or no urination, pain or burning when you urinate; 
6. Dehydration symptoms dizziness, tiredness, feeling very thirsty or hot, decreased sweating, or hot and dry skin; or 
7. High potassium level nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. 

Solifenacin treats overactive bladder by blocking acetylcholine, a chemical that squeezes bladder and causes contractions. This helps the bladder hold urine longer, relaxes its muscles, and reduces sudden urges, leakage, and frequent urination.

Pregnancy

It is not recommended to take solifenacin in pregnancy, as there are no studies supporting its safety in pregnant women, and animal studies have shown some serious effects on babies, like improper development and low birth weight. Consult a doctor before using it.

Kidney and Liver Problems

Patients with previous liver and kidney damage are not recommended to take the medicine, as it can cause liver and kidney toxicity while being removed from the body.

Breastfeeding

Solifenacin is generally not recommended during breastfeeding, especially for newborns or preterm infants, due to limited safety data and its long half-life.

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicine. Also tell your health care professional if you have any other types of allergies, such as foods, dyes, preservatives, or animals.

Heart Problems

Patients with a history of irregular heartbeat (arrhythmia) and heart problems are not recommended to take this medicine, as it can change blood pressure in patients sometimes. So, get a recommendation from a doctor before using it.

The use of drinks that contain alcohol raises your risk of low blood pressure from solifenacin. If you drink alcohol, talk to your doctor. You may need to have your blood pressure monitored while you take this drug.

Avoid taking Solifenacin 5 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

(3R)-1-azabicyclo [2.2.2] octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

Daily dose

Take Solifenacin exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 50 mg of solifenacin per day, as it may cause severe overdosing effects like kidney and liver damage, fatigue, blurred vision, mental changes, and dizziness. If you face any of the severe effects, please contact the doctor.

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

1. Take Solifenacin exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Solifenacin without your doctor’s approval, even if you feel better. 
3. If you forget to take Solifenacin, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Solifenacin is a muscarinic receptor antagonist medicine used to treat overactive bladder, a condition where you feel the sudden need to pee often or can’t hold it in. It works by calming down bladder nerves to reduce urgency and leaks. Most people take it once a day, with or without food. Common side effects of taking this medicine include dry mouth, constipation, and blurred vision. Avoid it if you have trouble passing urine, stomach issues like severe constipation, or certain eye problems like glaucoma. Also, don’t mix it with some antibiotics or antifungal medicines without a doctor’s advice, and drink enough water in hot weather since it can reduce sweat.

What are the uses of Solifenacin tablets?

Solifenacin is a muscarinic receptor antagonist medicine used to treat overactive bladder, a condition where you feel the sudden need to pee often or can’t hold it in. It works by calming down bladder nerves to reduce urgency and leaks.

What are the side effects of Solifenacin?

Common side effects of this medicine use include dry mouth, constipation, and blurred vision. Avoid it if you have trouble passing urine, stomach issues like severe constipation, or certain eye problems like glaucoma.

What is the mechanism of action of Solifenacin?

Solifenacin work by calming bladder nerves solifenacin blocks M3 receptors to reduce unwanted muscle contractions, leading to relaxation and expanded bladder capacity. In overactive bladder (OAB), this slows the “false alarm” signals and gives you longer, more comfortable control between bathroom visits. 

What is the recommended dose of solifenacin per day? 

It is recommended to take up to 30 mg of solifenacin per day without getting any side effects, and doses above 30 mg can cause severe side effects and may lead to mental health changes, confusion, dizziness, etc.

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