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| Uses | 1. To control acidity 2. To control heartburn 3. To control indigestion |
| Common Side Effects | 1. Dry mouth; 2. Increased thirst 3. Urinating more than usual. 4. Headache (continuing) 5. Loss of appetite (continuing) 6. Nausea or vomiting 7. Slow breathing 8. Swelling of feet or lower legs 9. Unpleasant taste 10. Unusual tiredness or weakness |
| Additional Information | 1. Patients with heart problems and blood pressure changes are not recommended to take this medicine, as it causes changes in blood pressure and heart functioning. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | To be taken orally with a sip of water |
Sodium bicarbonate 500 mg is an oral medicine belonging to the category of antacid drugs and is used for the following indications:
Sodium bicarbonate acts as a chemical buffer that neutralizes excess acid in the stomach and blood. In conditions like gastritis, heartburn, or metabolic acidosis (seen in kidney disease or diabetes), it releases bicarbonate ions that bind with hydrogen ions (acid), converting them into carbon dioxide and water, both easily removed by breathing or urination. This helps restore the body’s pH balance quickly and safely. For patients, think of it as your body’s natural firefighter calmly cooling the acid flames when things get too hot.
Sodium bicarbonate can relieve heartburn in pregnancy but should be used sparingly and only with medical advice. Its high sodium may worsen swelling or hypertension, and as an FDA Category C drug, safer alternatives are preferred. Always consult your doctor to protect mother and baby.
It’s unknown if sodium bicarbonate enters breast milk. If you are planning to breastfeed, consult your doctor about whether to continue the drug or breastfeeding.
Alcohol and smoking can simultaneously affect drug action, leading to an increase in the effect of the drug on the brain, so they may cause severe drowsiness and sedation as they act on the brain directly.
Avoid taking Sodium Bicarbonate 500 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Sodium Hydrogen carbonate

Take Sodium Bicarbonate exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
It is not recommended to take more than 25000 mg of sodium bicarbonate per day, as it may cause severe overdosing effects like high blood pressure, heart problems, drowsiness, sedation, and muscle problems. If you face any of the severe effects, take him to the doctor.
Sodium bicarbonate tablet is a medicine belonging to the category of antacids and used to relieve heartburn, indigestion, and acid buildup in the body. It works by neutralizing excess stomach acid and helping restore a healthy pH balance in blood and urine. This can also help remove certain toxins and prevent kidney stones. Common side effects may include bloating, nausea, increased thirst, or changes in salt levels. People with kidney problems, heart disease, high blood pressure or on low-sodium diets should avoid it unless prescribed. It may interfere with how some medicines work, like iron or antibiotics, and should not be taken with large amounts of dairy or acidic foods.
Sodium carbonate tablets are medicine belonging to the category of antacids and used to relieve heartburn, indigestion, and acid buildup in the body. It works by neutralizing excess stomach acid and helping restore a healthy pH balance in blood and urine. This can also help remove certain toxins and prevent kidney stones.
It is recommended to take to 16 grams of sodium bicarbonate based on the disease characteristics, like metabolic acidosis in kidney-damaged patients.
Common side effects of sodium bicarbonate may include bloating, nausea, increased thirst, or changes in salt levels.
Sodium bicarbonate works by stepping into your stomach like a calm firefighter. It soaks up the excess acid, cooling down that fiery burn after a spicy meal. This quick fix makes your chest feel less smoky and more relaxed.

Written By-
Siva Krishna Adithya BhumireddyMedical content writer
Bachelors in Pharmacy | 1+ Year experience

Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 18 Nov 2025
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