Repaglinide 1 mg is an oral medicine belonging to the category of antidiabetic drugs and is used to treat Type 2 Diabetes mellitus.

More Common  

1. Low blood sugar (see below) 
2. Infection in the nose or throat, sore throat 
3. Headache 
4. Stuffy or runny nose 
5. Joint pain 
6. Nausea 
7. Diarrhea 
8. Back pain 

Less Common 

1. Breathing problems or wheezing 
2. Racing heart 
3. Fever or general ill feeling 
4. Swollen lymph nodes 
5. Swelling of the face, lips, mouth, tongue, or throat 
6. Trouble swallowing or throat tightness 
7. Itching, skin rash, or pale red bumps on the skin called hives 
8. Nausea or vomiting 
9. Dizziness, feeling lightheaded, or fainting 
10. Stomach cramps 
11. Joint pain 
12. Suicidal thoughts 
13. Hallucinations 
14. Headache 
15. Crankiness or anxiety 
16. Hunger 
17. Dizziness or confusion 
18. Blurry vision 
19. Slurred speech 
20. Sweating 
21. Feeling jittery or shakiness 
22. Fast heartbeat 
23. Seizures

The pancreas is the main organ that releases insulin to maintain blood glucose levels in the body. In type 2 diabetes, the pancreas can’t produce sufficient insulin. Repaglinide acts directly on the pancreas by stimulating the release of good ions called calcium ions and preventing the outward flow of the potassium ions. This results in a buildup of ions in the pancreas, creating a charge that pushes the pancreas to produce extra insulin when food is taken. As a result, insulin is produced, glucose is utilized by the body, and blood glucose levels are reduced.

Pregnancy

Due to a lack of studies on the effects of repaglinide on the fetus during pregnancy, its safety is not clearly established. Therefore, if you are pregnant or planning to conceive, inform your doctor.

Breastfeeding

Repaglinide passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should stop breastfeeding or stop repaglinide.

Liver Problems and Kidney Problems

Patients suffering from kidney and liver problems are more prone to kidney and liver damage, as the drug is made into a less toxic form in the liver and kidney leading to strain on liver and kidney causing toxicity, so consult a doctor before using them.

Avoid smoking and consuming alcohol after taking this medicine, as they fluctuate the level of blood glucose levels by affecting the liver and pancreas.

Avoid taking Repaglinide 1 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

2-ethoxy-4-[2-[3-methyl -1-[2-(1-piperidinyl)phenyl]butyl]amino] benzoic acid

Daily dose

Take repaglinide exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 20 mg of Repaglinide per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, low blood pressure, unconsciousness, sweating, and seizures. Immediately give the eat fruit or glucose-containing liquids and sugary foods to minimize the effects. If you face any of the severe effects, seek medical help.

1. Store the medicine at room temperature.
2. Keep away from sunlight and moisture.
3. Keep out of reach of children.

1. Take repaglinide exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking repaglinide without your doctor’s approval, even if you feel better. 
3. If you forget to take repaglinide, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Repaglinide is an oral antidiabetic medicine that belongs to the meglitinide class. It works by stimulating the pancreas to release insulin, especially after meals, helping to control blood sugar levels in people with type 2 diabetes. Unlike some other diabetes medicines, repaglinide acts quickly and is taken just before eating to manage the rise in sugar that happens after meals. It’s mainly used to lower post-meal blood sugar spikes and can be especially helpful for people who follow irregular meal patterns. However, it’s important to eat soon after taking the tablet, as it can lower sugar levels too much, leading to a condition called hypoglycemia. Common side effects include mild dizziness, headache, and low blood sugar symptoms like sweating, shakiness, and hunger. In rare cases, stomach upset, and allergic reactions can occur. Finally, it should be taken at the prescribed levels only.

What is the mechanism of action of repaglinide?

Repaglinide is an antidiabetic medicine used to control high blood glucose levels, and it acts by stimulating the pancreas to stimulate more insulin that controls the blood sugar levels.

Which class of medicine does repaglinide belong to? 

Repaglinide belongs to the category of meglitinides, the antidiabetic drugs used to control blood glucose levels in the body effectively immediately after a meal.

What are the uses of repaglinide tablet 1 mg?

Repaglinide 1 mg is used to control blood sugar levels in adults who are in the early stage of diabetes and have less insulin release.

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