Pregabalin SR 75 mg is taken orally and belongs to antiseizure (anticonvulsant) class of medicine. It is approved for the treatment of nerve pain, muscle pain seizureand spinal cord nerve pain. 

You should take this medicine as instructed by your doctor which can be before and after meal or before or after sleep. Side effect of this medicine include dizziness, sleepiness, headache, tiredness, nausea and blurred vision. Do not skip using this medicine unless suggested by your doctor.

Inform your doctor if you are pregnant, breastfeeding or have weak muscle because if you have these condition then your doctor will prescribe you another medicine.

Pregabalin 75 mg is an oral medicine belonging to the class of anticonvulsant medicines. It is used for following indications: 

1. Nerve pain (Neuropathy pain)   
2. Muscle pain and fatigue (Fibromyalgia)  
3. Seizure/ Convulsion 
4. Spinal cord nerve pain 

1. Take pregabalin exactly as prescribed by your doctor, regularly at the same time each day. 
2. Do not stop taking pregabalin without your doctor’s approval, even if you feel better. 
3. If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it. 

More Common

1. Dizziness 
2. Sleepiness 
3. Headache 
4. Tiredness 
5. Fluid retention 
6. Nausea 
7. Blurred vision 
8. Dry mouth 
9. Weight gain 

Less Common

1. Chest pain or tightness 
2. cold sweats 
3. cool, pale skin 
4. cough producing mucus 
5. difficult or labored breathing 
6. muscle aches, twitching or jerking, or weakness 
7. noisy breathing 
8. seizures 

Pregabalin is a medicine designed to easily enter the brain, where it works like an electrician, calming overactive nerves. By reducing the excessive flow of electrical signals (voltage gated channel) responsible for pain and seizures, it helps restore balance and provides relief. 

Pregnancy

Pregabalin can cross the placenta and potentially harm the fetus. Therefore, patients should inform their doctor about their pregnancy or plans to conceive before using this medication.

Breastfeeding

If you are breastfeeding, avoid taking pregabalin, as it can pass into breast milk and may harm the baby.

Muscle damage

Clinical studies found that pregabalin can damage skeletal muscles, causing their contents to leak into the bloodstream.

Avoid taking pregabalin 75 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Pregabalin does not interact with any food products, but alcohol should be avoided before and after taking the medicine, as it can increase drowsiness and sleepiness. 

1. The medicine should be stored at room temperature  
2. Keep away from sunlight and moisture  
3. Keep away from the reach of children 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name-

(3S)-3-(aminomethyl)-5-methylhexanoic acid 

Daily dose

Take pregabalin exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

A pregabalin dose of 600 mg or higher is considered an overdose. Symptoms may include seizures, coma, or respiratory depression. Such cases require immediate medical attention to manage potential complications effectively.

1- Can pregabalin be taken long-term?

In cases of nerve injury caused by an accident, pregabalin can be used for long-term treatment. However, prolonged use may lead to addiction, and missing even a single dose can result in withdrawal symptoms such as anxiety, nausea, and difficulty sleeping. 

2- Can pregabalin cause constipation?

Yes, pregabalin can cause constipation, but the occurrence is quite rare. It can be managed with lifestyle changes (increased water, fiber, exercise) or with osmotic laxatives like polyethylene glycol or stimulant laxatives if needed. Always consult your healthcare provider before starting any laxative treatment. 

3- Can pregabalin and gabapentin be taken together?

Pregabalin and gabapentin are both anticonvulsant medications; however, they should not be taken together as this can increase the severity of side effects such as dizziness, sleepiness, and difficulty concentrating. 

4- Can pregabalin cause weight gain?

Yes, pregabalin can cause weight gain because it increases appetite, leading to a higher intake of food and subsequent weight gain. 

5- Can pregabalin increase creatinine?

Pregabalin can cause higher creatinine levels, but this usually happens in people with kidney problems. If creatinine levels are high, it means the body is having trouble getting excreting pregabalin.

6- Are pregabalin and gabapentin the same?

Pregabalin and gabapentin are both used to treat seizures, but they differ in how quickly they are absorbed into the bloodstream. Pregabalin is absorbed faster and takes effect more quickly compared to gabapentin. 

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