Mirabegron 25 mg (ER) is an oral medicine belonging to the category of beta-3 agonists and is used for the following indications:

1. Overactive bladder 
2. Bladder leakage 
3. Unable to hold urine 

More Common  

1. Bladder pain 
2. Bloody or cloudy urine 
3. Blurred vision 
4. Difficult, burning, or painful urination 
5. Dizziness 
6. Frequent urge to urinate 
7. Headache 
8. Lower back or side pain 
9. Nervousness 
10. Pounding in the ears 
11. Slow, fast, or irregular heartbeat 

Less Common 

1. Back pain 
2. Body aches or pain 
3. Constipation 
4. Difficulty having a bowel movement 
5. Difficulty with breathing 
6. Difficulty with moving 
7. Dry mouth 
8. Ear congestion 
9. Fever 
10. General feeling of discomfort or illness 
11. Loss of voice 
12. Muscle ache or stiffness 
13. Shivering 
14. Sneezing 
15. Stomach pain 
16. Stuffy or runny nose 
17. Sweating 

Mirabegron works by calming the overactive bladder muscle responsible for frequent urination. Mirabegron targets beta‑3 receptors on the bladder wall, which signals the muscle to relax and stretch more easily. This allows the bladder to hold more urine without triggering sudden urges, reducing frequent trips to the bathroom.

Pregnancy

Due to a lack of studies in pregnant women, it is not recommended for use in them. However, animal studies suggest some serious effects on babies, like improper development and low birth weight. Consult a doctor before using it.

Kidney and Liver Problems

Patients with previous liver and kidney damage are not recommended to take this medicine, as it can cause liver and kidney toxicity while being removed from the body.

Breastfeeding

Long-term use of mirabegron might reduce milk production. It is not known whether mirabegron passes into breast milk. Since it remains in the body for a long time, there are chances that it may be passed on to your infant. As there is not adequate data to prove its safety and efficacy in humans while breastfeeding, it is best to consult your doctor before taking this medicine.

The use of drinks that contain alcohol raises your risk of low blood pressure from mirabegron. If you drink alcohol, talk to your doctor. You may need to have your blood pressure monitored while you take this drug.

Avoid taking Mirabegron 25 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl] amino} ethyl) phenyl] acetamide.

Daily dose

Take mirabegron exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than 400 mg (ER) of mirabegron per day, as it may cause severe overdosing effects like kidney and liver damage, palpitations, blurred vision, blood pressure, and dizziness. If you face any of the severe effects, meet the doctor.

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

1. Take Mirabegron exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking Mirabegron without your doctor’s approval, even if you feel better. 
3. If you forget to take Mirabegron, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. 

Mirabegron is a medicine from the beta‑3 adrenergic agonist class, used to treat overactive bladder (OAB), a condition where you feel a frequent, sudden urge to urinate that’s hard to control. It works by relaxing the bladder muscle, allowing it to hold more urine and reducing the need to rush to the toilet. Common side effects include high blood pressure, headache, dry mouth, constipation, and fast heartbeat (especially when combined with solifenacin). People with uncontrolled hypertension, severe liver or kidney problems, or urinary retention should avoid it. It can be taken with or without food, but children should take it with meals; alcohol may worsen side effects, so caution is advised. Doses around or above 400 mg may trigger dangerous overdose effects such as irregular heartbeat or severe dizziness.

What are the uses of Mirabegron tablets?

Mirabegron is a medicine used to treat overactive bladder (OAB), a condition where you feel a frequent, sudden urge to urinate that’s hard to control. It works by relaxing the bladder muscle, allowing it to hold more urine and reducing the need to rush to the toilet.

What are the side effects of Mirabegron?

Common side effects of mirabegron use include high blood pressure, headache, dry mouth, constipation, and fast heartbeat.

What is the mechanism of action of Mirabegron?

Mirabegron works by calming bladder nerves to reduce unwanted muscle contractions and activates β3 receptors to relax and expand bladder capacity. In overactive bladder (OAB), this duo slows the “false alarm” signals and gives you longer, more comfortable control between bathroom visits.

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