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Indapamide 1.5 mg is a thiazide‑like diuretic (“water pill”) prescribed mainly for high blood pressure and swelling, sometimes off‑label for kidney stones or resistant hypertension; it works by restricting the accumulation of salt in the kidneys, so more salt and water are flushed out, lowering pressure and fluid. Common side effects include frequent urination, dizziness, headache, fatigue, nausea, constipation, low potassium, sun sensitivity, gout, and high blood sugar. Alcohol, NSAIDs, and lithium can interfere with its action, while low‑salt diets or potassium supplements may be advised. Extra care is needed in older adults, people with diabetes, gout, or liver/kidney problems. Overdose occurs at 200 to 400 mg and can cause severe dehydration, dangerously low blood pressure, electrolyte collapse, and heart rhythm disturbances requiring urgent medical care.
| Uses | 1. To control high blood pressure 2. To control swelling in legs in heart patients |
| Common Side Effects | 1. Urination 2. Dizziness 3. Headache 4. Fatigue 5. Nausea 6. Constipation 7. Hypokalemia 8. Photosensitivity 9. Gout 10. Hyperglycemia |
| Additional Information | 1. Patients are recommended to limit salt intake, as it can be contraindicated and reduce drug action. |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water. |
Indapamide 1.5 mg is used for the management of high blood pressure and to control swellings related to it.
Indapamide 1.5 mg works by reducing the accumulation of salt in the kidneys and helps the body get rid of excess salt and water through urine, like opening a drain to release pressure. When less fluid remains in the blood vessels, the heart does not have to pump as hard, and swelling decreases. This makes it useful for controlling high blood pressure and fluid buildup.
The safety of Indapamide 1.5 mg in pregnancy is not established, and it can cause jaundice, low platelet counts, and diarrhea in patients. Inform your doctor if you are pregnant or planning to conceive.
Indapamide 1.5 mg is not usually recommended during breastfeeding because there is no reliable information on whether it passes into breast milk or how it might affect a nursing infant.
Indapamide 1.5 mg should be used cautiously in kidney disease, as weak kidneys may not clear it well, causing dehydration and electrolyte problems. In liver disease, it can upset fluid balance and, in severe cases, trigger hepatic coma. Overall, it is avoided in severe kidney or liver problems but may be used with close monitoring in milder cases.
Avoid consuming alcohol and smoking simultaneously, as it may affect the drug’s action and show an effect on the brain, leading to severe drowsiness, sedation, and coma in severe cases.
Avoid taking Indapamide 1.5 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
(RS)-2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide.

Take Indapamide 1.5 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
It is not recommended to take more than 20 mg of Indapamide per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.
Indapamide 1.5 mg tablets are mainly used to treat high blood pressure and reduce fluid buildup (edema) caused by heart failure, kidney disease, or liver problems. They may also be used off‑label for conditions like kidney stones or resistant hypertension under medical supervision.
Indapamide 1.5 mg tablets can cause frequent urination, dizziness, headache, fatigue, nausea, constipation, low potassium, sun sensitivity, gout, and raised blood sugar. Less common effects include rash, muscle cramps, weakness, impotence, insomnia, and liver or pancreas problems, all of which need medical attention if severe.
Indapamide 1.5 mg belongs to the drug class of thiazide diuretics and can show vascular effects.
The maximum recommended dose of Indapamide is 100 mg once daily, though most patients respond well at lower doses. Higher doses increase the risk of side effects like dehydration and electrolyte imbalance without adding much extra benefit.

Written By-
Siva Krishna Adithya BhumireddyMedical content writer
Bachelors in Pharmacy | 1+ Year experience

Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 12 Jul 2026
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