Framycetin 1% Cream is a topical antibiotic cream used to treat bacterial skin infections such as infected cuts, wounds, burns, boils, ulcers, and infected skin conditions. It works by stopping the growth of bacteria and preventing the infection from spreading. It also helps reduce redness, swelling, irritation, pain, and discharge from infected skin areas. 

Common side effects of Framycetin 1% Cream include mild skin irritation, redness, itching, burning sensation, or dryness at the application site. Rarely, it may cause allergic reactions such as rash or swelling. It should be avoided in people who are allergic to Framycetin or other aminoglycoside antibiotics. 

Using more than the recommended amount may increase the risk of skin irritation or allergic reactions. Always use this medicine exactly as prescribed and consult your doctor if severe symptoms occur.     

Framycetin 1% Cream is used to treat following conditions: 

1. Bacterial skin infections 
2. Infected cuts and wounds 
3. Minor burns and ulcers 
4. Infected eczema and skin irritation          

More Common

1. Skin irritation 
2. Itching 
3. Redness 
4. Burning sensation 
5. Dryness of skin        

Less Common 

1. Allergic reaction (rash, swelling, breathing difficulty) 
2. Severe skin irritation 
3. Skin sensitivity        

Framycetin 1% Cream works by stopping the growth of bacteria on the skin. It belongs to a group of medicines called aminoglycoside antibiotics. The medicine damages bacterial protein production, which kills the bacteria causing the infection. This helps reduce redness, swelling, pain, and irritation while supporting faster healing of infected skin areas. 

Allergy / Hypersensitivity

If you are allergic to Framycetin 1% or aminoglycoside antibiotics, avoid using this cream because it may cause serious allergic reactions like rash, itching, swelling, or breathing problems. Always communicate with your doctor before use. 

Skin Conditions

Avoid applying Framycetin 1% Cream on large open wounds, deep burns, or severe skin damage unless advised by your doctor.

Pregnancy

If you are pregnant or planning pregnancy, consult your doctor before using Framycetin 1% Cream.

Breastfeeding

If you are breastfeeding, use only if advised by your doctor and avoid applying near the chest area.

Since Framycetin 1% Cream is applied on the skin, there are no major food interactions known with this medicine.  

Avoid taking Framycetin 1% with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Framycetin: (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol

Daily dose

Take Framycetin 1% exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than prescribed dose of Framycetin 1%. Using excessive amounts may cause skin irritation, redness, itching, or allergic reactions. Seek medical advice if severe symptoms occur.

1. Store the medicine at room temperature. 
2. Keep away from sunlight and moisture. 
3. Keep out of reach of children 

1. Clean and dry the affected area before application. 
2. Apply a thin layer of Framycetin 1% Cream on the affected skin. 
3. Use exactly as prescribed by your doctor. 
4. Do not apply excessively or on large skin areas unless advised. 
5. Wash hands before and after application. 
6. Avoid contact with eyes, mouth, and open deep wounds.  

What are the side effects of Framycetin 1% Cream? 

Framycetin 1% Cream may cause skin irritation, redness, itching, burning sensation, dryness, or rash. Rarely, allergic reactions may occur. 

What class of drug does Framycetin 1% Cream belong to? 

Framycetin belongs to the class of aminoglycoside antibiotics used to treat bacterial infections. 

What is the mechanism of action of Framycetin 1% Cream? 

Framycetin works by stopping bacterial protein production, which kills the bacteria and helps treat skin infections. 

What are the uses of Framycetin 1% Cream? 

It is used to treat bacterial skin infections, infected cuts, wounds, burns, ulcers, and infected skin irritation. 

1. PubChem. Neomycin [Internet]. Nih.gov. PubChem; 2026 [cited 2026 May 22]. Available from 
2. Framycetin – an overview | ScienceDirect Topics [Internet]. www.sciencedirect.com. Available from 
3. Framycetin [Internet]. go.drugbank.com. Available from