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Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg tablet is used to treat high blood pressure and chest pain due to poor blood flow to the heart. It helps by relaxing blood vessels and improving circulation, which eases the heart’s workload. Common side effects of Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg are headaches, dizziness, swollen ankles, and sometimes tummy discomfort or skin rashes. People with serious liver problems, very low blood pressure, or heart issues, or women who are pregnant or breastfeeding, should inform their doctor before using it. Drinking grapefruit juice with this medication makes it stronger and increases side effects, so it’s best skipped. Always store this medicine in a cool, dry place away from sunlight, and keep it in its original packaging. Taking more than 100 mg of this medicine daily can cause overdosing effects like severe hypotension, dizziness, fainting, and potentially life-threatening cardiovascular collapse.
| Uses | 1. To treat high blood pressure 2. To prevent heart attacks. |
| Common Side Effects | 1. Headache 2. Dizziness 3. Constipation 4. Skin rash 5. Decreased blood pressure 6. Nausea |
| Additional Information | 1. Take medicine every day at the same time to maintain the drug well in the blood. 2. Do not stop the medicine usage suddenly |
| Storage | 1. The medicine should be stored at room temperature. 2. Keep away from sunlight and moisture. 3. Keep away from the reach of children |
| How to Take This Medicine | Take this medicine orally with a sip of water |
Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg is used to treat high blood pressure and chest pain related to it.
Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg works by helping the blood vessels relax and widen, which makes it easier for blood to flow and lowers blood pressure. It blocks three types of calcium channels—L-type, T-type, and N-type that normally tighten blood vessels and make the heart work harder. It also reduces angiotensin, which causes blood pressure.
Pregnant women are not recommended to take Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg, as there are no human studies supporting its safety during pregnancy. In case of an emergency, consult a doctor before using it.
Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg can pass into breast milk, so it’s used with caution during breastfeeding. Other safer options are usually tried first. If it is needed, the baby should be watched closely for any changes like diarrhea or sleepiness. Always talk to your doctor before using it.
Patients suffering from kidney and liver problems are more prone to kidney and liver damage, as the medicine is converted into a less toxic form in the liver and excreted through the kidney. They may cause interactions and cause severe toxicity, so consult a doctor before using them
Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg is generally safe with food, and it is recommended to avoid alcohol and smoking with Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg, as they can alter the drug’s effect and may cause severe drowsiness and sedation because of their direct action on the brain.
Avoid taking Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:
Cilnidpine-3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Olmesartan- 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid

Chlorthalidone- 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide

Take Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.
If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.
It is not recommended to take more than 200 mg of Cilnidipine + Olmesartan + Chlorthalidone per day, as it may cause severe overdosing effects like extreme drowsiness, confusion, unconsciousness, sweating, double vision, low blood pressure, and slurred speech. Immediately seek medical attention and meet the doctor if necessary.
mechanism of action works by helping the blood vessels relax and widen, which makes it easier for blood to flow and lowers blood pressure. It blocks three types of calcium channels like L-type, T-type, and N-type that normally tighten blood vessels and make the heart work harder. By easing these signals, Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg opens the pathways and lightens the heart’s load.
Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg are medicines used to treat high blood pressure and chest pain due to poor blood flow to the heart. It helps by relaxing blood vessels and improving circulation, which eases the heart’s workload.
Common side effects of Cilnidipine 10 mg + Olmesartan 20 mg + Chlorthalidone 12.5 mg use include headaches, dizziness, swollen ankles, and sometimes tummy discomfort or skin rashes.

Written By-
Siva Krishna Adithya BhumireddyMedical content writer
Bachelors in Pharmacy | 1+ Year experience

Reviewed By-
Mahak PhartyalMedical Content writer and reviewer
Bachelors in Pharmacy | 3+ Year experience
Last Updated: 15 Jul 2026
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