Cefuroxime is an antibiotic that belongs to the cephalosporin class of drugs. It is used to treat bacterial infections such as chest infections (pneumonia, bronchitis), sinus infections, throat infections (tonsillitis, pharyngitis), ear infections, urinary tract and kidney infections, and skin or soft tissue infections. It works by attacking the bacteria’s cell wall, causing the bacteria to burst and die. Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, dizziness, or mild skin rash. Rare but serious side effects may include severe allergic reactions, severe diarrhea from gut infection, liver problems, or unusual bruising or bleeding.  

Cefuroxime should not be taken by people allergic to cephalosporins or with a history of severe allergic reactions to penicillin. It is generally considered safe in pregnancy if prescribed by a doctor. Take it with water and avoid milk, dairy, or high-calcium foods at the same time to ensure it works effectively. Always inform your doctor about allergies, medical history, or pregnancy before taking this medicine.  

Cefuroxime 250 mg is used to kill bacteria and treat symptoms of conditions like: 

1. Chest infections such as pneumonia and bronchitis 
2. Sinus infections (sinusitis) 
3. Throat infections like tonsillitis or pharyngitis 
4. Ear infections (otitis media) 
5. Urinary tract and kidney infections 
6. Skin and soft tissue infections, like infected wounds or cellulitis   

1. Take this medicine exactly as prescribed by your doctor, at the same time each day. 
2. Do not stop taking this medicine without your doctor’s approval, even if you feel better. 
3. If you forget to take this medicine, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose.  

More Common  

1. Nausea or vomiting 
2. Diarrhea or loose stools 
3. Stomach pain or upset stomach 
4. Headache 
5. Dizziness 
6. Skin rash or itching    

Less Common

1. Severe allergic reactions (swelling, difficulty breathing, severe rash) 
2. Severe diarrhea caused by Clostridium difficile (infection in the gut) 
3. Liver problems (yellowing of skin or eyes) 
4. Blood-related issues (unusual bruising or bleeding)   

Cefuroxime works by attacking the bacteria’s cell wall. It stops the bacteria from building a strong outer wall, which is essential for their survival. Without this wall, the bacteria burst and die, helping the body fight the infection. 

Allergy Warning

Avoid Cefuroxime if you are allergic to cefuroxime or other cephalosporin antibiotics. Taking it may cause severe allergic reactions like swelling, breathing difficulty, or dangerous rashes. Inform your doctor about any past drug allergies. 

Severe Kidney Problems

Use Cefuroxime with caution if you have severe kidney disease. The medicine may build up in the body and cause side effects. Tell your doctor about any kidney-related conditions so the dose can be adjusted properly. 

History of Severe Allergic Reactions or Anaphylaxis

 Avoid Cefuroxime if you have had severe allergic reactions to penicillin or other beta-lactam antibiotics, as cross-reactions may occur. Always inform your doctor before starting treatment. 

Cefuroxime can be taken with or without food but taking it with milk or dairy products may slightly reduce how well the medicine is absorbed. To get the best effect, try to take it with water and avoid high-calcium foods or supplements at the same time. 

Avoid taking Cefuroxime 250 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

IUPAC (International Union of Pure and Applied Chemistry) / Chemical name

Cefuroxime: (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Daily dose

Take Cefuroxime 250 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor. 

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage. 

Overdose

It is not recommended to take more than 1 gram of Cefuroxime per day. Overdose may cause tremors, chest pain, fast or irregular heartbeat, nervousness, dizziness, headache, muscle cramps, or high blood pressure. In case of any of these symptoms, seek immediate medical help. 

1. Store the medicine at room temperature 
2. Keep away from sunlight and moisture 
3. Keep out of reach of children 

What are the uses of Cefuroxime 250 mg?

Cefuroxime 250 mg is an antibiotic used to treat different bacterial infections in the body. It helps with chest infections like pneumonia and bronchitis, sinus infections, throat infections such as tonsillitis or pharyngitis, ear infections, urinary tract and kidney infections, and skin or soft tissue infections like infected wounds. 

What are the side effects of Cefuroxime 250 mg? 

Cefuroxime 250 mg may cause some common side effects like nausea, vomiting, diarrhea, stomach pain, headache, dizziness, or mild skin rash. Rare but serious side effects can include severe allergic reactions, severe diarrhea caused by gut infection, liver problems (yellowing of skin or eyes), or unusual bruising and bleeding. If any serious symptoms appear, contact your doctor immediately. 

How does Cefuroxime 250 mg work? 

Cefuroxime works by attacking the bacteria’s cell wall. It stops the bacteria from making a strong outer wall, which is essential for their survival. Without this wall, the bacteria burst and die, helping the body fight the infection. 

1. Cefuroxime Dosage Guide + Max Dose, Adjustments [Internet]. Drugs.com. Available from 
2. Omole AE, Awosika AO, Patel P. Cefuroxime [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2024. Available from 
3. PubChem. Cefuroxime [Internet]. Nih.gov. PubChem; 2025 [cited 2025 Dec 10]. Available from